Characterization of Micro-RNA Changes during the Progression of Type 2 Diabetes in Zucker Diabetic Fatty Rats

por Delic, Denis, Eisele, Claudia, Schmid, Ramona, Luippold, Gerd, Mayoux, Eric, Grempler, Rolf
Publicado 2016

The Effects of Empagliflozin, an SGLT2 Inhibitor, on Pancreatic β-Cell Mass and Glucose Homeostasis in Type 1 Diabetes

por Cheng, Sam Tsz Wai, Chen, Lihua, Li, Stephen Yu Ting, Mayoux, Eric, Leung, Po Sing
Publicado 2016

SGLT2 Inhibition by Empagliflozin Promotes Fat Utilization and Browning and Attenuates Inflammation and Insulin Resistance by Polarizing M2 Macrophages in Diet-induced Obese Mice

por Xu, Liang, Nagata, Naoto, Nagashimada, Mayumi, Zhuge, Fen, Ni, Yinhua, Chen, Guanliang, Mayoux, Eric, Kaneko, Shuichi, Ota, Tsuguhito
Publicado 2017

Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese r...

por Vickers, Steven P, Cheetham, Sharon C, Headland, Katie R, Dickinson, Keith, Grempler, Rolf, Mayoux, Eric, Mark, Michael, Klein, Thomas
Publicado 2014

Angiotensin II‐induced redox‐sensitive SGLT1 and 2 expression promotes high glucose‐induced endothelial cell senescence

por Khemais‐Benkhiat, Sonia, Belcastro, Eugenia, Idris‐Khodja, Noureddine, Park, Sin‐Hee, Amoura, Lamia, Abbas, Malak, Auger, Cyril, Kessler, Laurence, Mayoux, Eric, Toti, Florence, Schini‐Kerth, Valérie B.
Publicado 2019

Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function in a female rodent model of diabetes

por Habibi, Javad, Aroor, Annayya R., Sowers, James R., Jia, Guanghong, Hayden, Melvin R., Garro, Mona, Barron, Brady, Mayoux, Eric, Rector, R. Scott, Whaley-Connell, Adam, DeMarco, Vincent G.
Publicado 2017

Empagliflozin Increases Cardiac Energy Production in Diabetes: Novel Translational Insights Into the Heart Failure Benefits of SGLT2 Inhibitors

por Verma, Subodh, Rawat, Sonia, Ho, Kim L., Wagg, Cory S., Zhang, Liyan, Teoh, Hwee, Dyck, John E., Uddin, Golam M., Oudit, Gavin Y., Mayoux, Eric, Lehrke, Michael, Marx, Nikolaus, Lopaschuk, Gary D.
Publicado 2018

The Sodium-Glucose Co-Transporter 2 Inhibitor Empagliflozin Improves Diabetes-Induced Vascular Dysfunction in the Streptozotocin Diabetes Rat Model by Interfering with Oxidative St...

por Oelze, Matthias, Kröller-Schön, Swenja, Welschof, Philipp, Jansen, Thomas, Hausding, Michael, Mikhed, Yuliya, Stamm, Paul, Mader, Michael, Zinßius, Elena, Agdauletova, Saule, Gottschlich, Anna, Steven, Sebastian, Schulz, Eberhard, Bottari, Serge P., Mayoux, Eric, Münzel, Thomas, Daiber, Andreas
Publicado 2014

Empagliflozin improved systolic blood pressure, endothelial dysfunction and heart remodeling in the metabolic syndrome ZSF1 rat

por Park, Sin-Hee, Farooq, Muhammad Akmal, Gaertner, Sébastien, Bruckert, Christophe, Qureshi, Abdul Wahid, Lee, Hyun-Ho, Benrahla, Djamel, Pollet, Brigitte, Stephan, Dominique, Ohlmann, Patrick, Lessinger, Jean-Marc, Mayoux, Eric, Auger, Cyril, Morel, Olivier, Schini-Kerth, Valérie B.
Publicado 2020

Glycemic control by the SGLT2 inhibitor empagliflozin decreases aortic stiffness, renal resistivity index and kidney injury

por Aroor, Annayya R., Das, Nitin A., Carpenter, Andrea J., Habibi, Javad, Jia, Guanghong, Ramirez-Perez, Francisco I., Martinez-Lemus, Luis, Manrique-Acevedo, Camila M., Hayden, Melvin R., Duta, Cornel, Nistala, Ravi, Mayoux, Eric, Padilla, Jaume, Chandrasekar, Bysani, DeMarco, Vincent G.
Publicado 2018

The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF rats

por Steven, Sebastian, Oelze, Matthias, Hanf, Alina, Kröller-Schön, Swenja, Kashani, Fatemeh, Roohani, Siyer, Welschof, Philipp, Kopp, Maximilian, Gödtel-Armbrust, Ute, Xia, Ning, Li, Huige, Schulz, Eberhard, Lackner, Karl J., Wojnowski, Leszek, Bottari, Serge P., Wenzel, Philip, Mayoux, Eric, Münzel, Thomas, Daiber, Andreas
Publicado 2017

SGLT2 is not expressed in pancreatic α- and β-cells, and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans

por Chae, Heeyoung, Augustin, Robert, Gatineau, Eva, Mayoux, Eric, Bensellam, Mohammed, Antoine, Nancy, Khattab, Firas, Lai, Bao-Khanh, Brusa, Davide, Stierstorfer, Birgit, Klein, Holger, Singh, Bilal, Ruiz, Lucie, Pieper, Michael, Mark, Michael, Herrera, Pedro L., Gribble, Fiona M., Reimann, Frank, Wojtusciszyn, Anne, Broca, Christophe, Rita, Nano, Piemonti, Lorenzo, Gilon, Patrick
Publicado 2020