The Establishment of the Pfizer-Canine Comparative Oncology and Genomics Consortium Biospecimen Repository

por Mazcko, Christina, Thomas, Rachael
Publicado 2015

Addendum: Mazcko, C., et al. The Establishment of the Pfizer-Canine Comparative Oncology and Genomics Consortium Biospecimen Repository. Vet. Sci. 2015, 2, 127–130

por Mazcko, Christina, Thomas, Rachael
Publicado 2015

The Comparative Oncology Trials Consortium: Using Spontaneously Occurring Cancers in Dogs to Inform the Cancer Drug Development Pathway

por Gordon, Ira, Paoloni, Melissa, Mazcko, Christina, Khanna, Chand
Publicado 2009

Deep Domain Adversarial Learning for Species-Agnostic Classification of Histologic Subtypes of Osteosarcoma

por Patkar, Sushant, Beck, Jessica, Harmon, Stephanie, Mazcko, Christina, Turkbey, Baris, Choyke, Peter, Brown, G. Thomas, LeBlanc, Amy
Publicado 2023

Transcriptomic profiling in canines and humans reveals cancer specific gene modules and biological mechanisms common to both species

por Tawa, Gregory J., Braisted, John, Gerhold, David, Grewal, Gurmit, Mazcko, Christina, Breen, Matthew, Sittampalam, Gurusingham, LeBlanc, Amy K.
Publicado 2021

Large Scale Comparative Deconvolution Analysis of the Canine and Human Osteosarcoma Tumor Microenvironment Uncovers Conserved Clinically Relevant Subtypes

por Patkar, Sushant, Mannheimer, Josh, Harmon, Stephanie, Mazcko, Christina, Choyke, Peter, Brown, G Tom, Turkbey, Baris, LeBlanc, Amy, Beck, Jessica
Publicado 2023

Development of a quantitative pharmacodynamic assay for apoptosis in fixed tumor tissue and its application in distinguishing cytotoxic drug—induced DNA double strand breaks from D...

por Dull, Angie B., Wilsker, Deborah, Hollingshead, Melinda, Mazcko, Christina, Annunziata, Christina M., LeBlanc, Amy K., Doroshow, James H., Kinders, Robert J., Parchment, Ralph E.
Publicado 2018

Transcriptional profiling of canine osteosarcoma identifies prognostic gene expression signatures with translational value for humans

por Mannheimer, Joshua D., Tawa, Gregory, Gerhold, David, Braisted, John, Sayers, Carly M., McEachron, Troy A., Meltzer, Paul, Mazcko, Christina, Beck, Jessica A., LeBlanc, Amy K.
Publicado 2023

Rapamycin Pharmacokinetic and Pharmacodynamic Relationships in Osteosarcoma: A Comparative Oncology Study in Dogs

por Paoloni, Melissa C., Mazcko, Christina, Fox, Elizabeth, Fan, Timothy, Lana, Susan, Kisseberth, William, Vail, David M., Nuckolls, Kaylee, Osborne, Tanasa, Yalkowsy, Samuel, Gustafson, Daniel, Yu, Yunkai, Cao, Liang, Khanna, Chand
Publicado 2010

Launching a Novel Preclinical Infrastructure: Comparative Oncology Trials Consortium Directed Therapeutic Targeting of TNFα to Cancer Vasculature

por Paoloni, Melissa C., Tandle, Anita, Mazcko, Christina, Hanna, Engy, Kachala, Stefan, LeBlanc, Amy, Newman, Shelley, Vail, David, Henry, Carolyn, Thamm, Douglas, Sorenmo, Karin, Hajitou, Amin, Pasqualini, Renata, Arap, Wadih, Khanna, Chand, Libutti, Steven K.
Publicado 2009

Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma

por Paoloni, Melissa, Mazcko, Christina, Selting, Kimberly, Lana, Susan, Barber, Lisa, Phillips, Jeffrey, Skorupski, Katherine, Vail, David, Wilson, Heather, Biller, Barbara, Avery, Anne, Kiupel, Matti, LeBlanc, Amy, Bernhardt, Anna, Brunkhorst, Beatrice, Tighe, Robert, Khanna, Chand
Publicado 2015

Prospective Molecular Profiling of Canine Cancers Provides a Clinically Relevant Comparative Model for Evaluating Personalized Medicine (PMed) Trials

por Paoloni, Melissa, Webb, Craig, Mazcko, Christina, Cherba, David, Hendricks, William, Lana, Susan, Ehrhart, E. J., Charles, Brad, Fehling, Heather, Kumar, Leena, Vail, David, Henson, Michael, Childress, Michael, Kitchell, Barbara, Kingsley, Christopher, Kim, Seungchan, Neff, Mark, Davis, Barbara, Khanna, Chand, Trent, Jeffrey
Publicado 2014

A Comparative Oncology Study of Iniparib Defines Its Pharmacokinetic Profile and Biological Activity in a Naturally-Occurring Canine Cancer Model

por Saba, Corey, Paoloni, Melissa, Mazcko, Christina, Kisseberth, William, Burton, Jenna H., Smith, Annette, Wilson-Robles, Heather, Allstadt, Sara, Vail, David, Henry, Carolyn, Lana, Susan, Ehrhart, E. J., Charles, Brad, Kent, Michael, Lawrence, Jessica, Burgess, Kristine, Borgatti, Antonella, Suter, Steve, Woods, Paul, Gordon, Ira, Vrignaud, Patricia, Khanna, Chand, LeBlanc, Amy K.
Publicado 2016

Comparative Oncology Assessment of a Novel Inhibitor of Valosin-Containing Protein in Tumor-Bearing Dogs

por LeBlanc, Amy K., Mazcko, Christina N., Fan, Timothy M., Vail, David M., Flesner, Brian K., Bryan, Jeffrey N., Li, Shan, Wang, Feng, Harris, Scott, Vargas, Jesse D., Govindharajulu, Jeevan P., Jaganathan, Soumya, Tomaino, Francesca, Srivastava, Apurva K., Chou, Tsui-Fen, Stott, Gordon M., Covey, Joseph M., Mroczkowski, Barbara, Doroshow, James H.
Publicado 2022

Veterinary Cooperative Oncology Group—Common Terminology Criteria for Adverse Events (VCOG‐CTCAE v2) following investigational therapy in dogs and cats

por LeBlanc, Amy K., Atherton, Matthew, Bentley, R. Timothy, Boudreau, C. Elizabeth, Burton, Jenna H., Curran, Kaitlin M., Dow, Steven, Giuffrida, Michelle A., Kellihan, Heidi B., Mason, Nicola J., Oblak, Michelle, Selmic, Laura E., Selting, Kimberly A., Singh, Ameet, Tjostheim, Sonja, Vail, David M., Weishaar, Kristen M., Berger, Erika P., Rossmeisl, John H., Mazcko, Christina
Publicado 2021