A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity

por Bardelli, Marco, Frontzek, Karl, Simonelli, Luca, Hornemann, Simone, Pedotti, Mattia, Mazzola, Federica, Carta, Manfredi, Eckhardt, Valeria, D’Antuono, Rocco, Virgilio, Tommaso, González, Santiago F., Aguzzi, Adriano, Varani, Luca
Publicado 2018

A conformational switch controlling the toxicity of the prion protein

por Frontzek, Karl, Bardelli, Marco, Senatore, Assunta, Henzi, Anna, Reimann, Regina R., Bedir, Seden, Marino, Marika, Hussain, Rohanah, Jurt, Simon, Meisl, Georg, Pedotti, Mattia, Mazzola, Federica, Siligardi, Giuliano, Zerbe, Oliver, Losa, Marco, Knowles, Tuomas, Lakkaraju, Asvin, Zhu, Caihong, Schwarz, Petra, Hornemann, Simone, Holt, Matthew G., Simonelli, Luca, Varani, Luca, Aguzzi, Adriano
Publicado 2022

Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies

por Linsenmeier, Luise, Mohammadi, Behnam, Shafiq, Mohsin, Frontzek, Karl, Bär, Julia, Shrivastava, Amulya N., Damme, Markus, Song, Feizhi, Schwarz, Alexander, Da Vela, Stefano, Massignan, Tania, Jung, Sebastian, Correia, Angela, Schmitz, Matthias, Puig, Berta, Hornemann, Simone, Zerr, Inga, Tatzelt, Jörg, Biasini, Emiliano, Saftig, Paul, Schweizer, Michaela, Svergun, Dmitri, Amin, Ladan, Mazzola, Federica, Varani, Luca, Thapa, Simrika, Gilch, Sabine, Schätzl, Hermann, Harris, David A., Triller, Antoine, Mikhaylova, Marina, Aguzzi, Adriano, Altmeppen, Hermann C., Glatzel, Markus
Publicado 2021

Publisher Correction: Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice

por De Gasparo, Raoul, Pedotti, Mattia, Simonelli, Luca, Nickl, Petr, Muecksch, Frauke, Cassaniti, Irene, Percivalle, Elena, Lorenzi, Julio C. C., Mazzola, Federica, Magrì, Davide, Michalcikova, Tereza, Haviernik, Jan, Honig, Vaclav, Mrazkova, Blanka, Polakova, Natalie, Fortova, Andrea, Tureckova, Jolana, Iatsiuk, Veronika, Di Girolamo, Salvatore, Palus, Martin, Zudova, Dagmar, Bednar, Petr, Bukova, Ivana, Bianchini, Filippo, Mehn, Dora, Nencka, Radim, Strakova, Petra, Pavlis, Oto, Rozman, Jan, Gioria, Sabrina, Sammartino, Josè Camilla, Giardina, Federica, Gaiarsa, Stefano, Pan-Hammarström, Qiang, Barnes, Christopher O., Bjorkman, Pamela J., Calzolai, Luigi, Piralla, Antonio, Baldanti, Fausto, Nussenzweig, Michel C., Bieniasz, Paul D., Hatziioannou, Theodora, Prochazka, Jan, Sedlacek, Radislav, Robbiani, Davide F., Ruzek, Daniel, Varani, Luca
Publicado 2021