Interleukin-6: obstacles to targeting a complex cytokine in critical illness

por McElvaney, Oliver J, Curley, Gerard F, Rose-John, Stefan, McElvaney, Noel G
Publicado 2021

Reply to Blot et al. and to Inoue et al.

por McElvaney, Oliver J., McEvoy, Natalie L., McElvaney, Noel G., Curley, Gerard F.
Publicado 2021

Targeting IgG Autoantibodies for Improved Cytotoxicity of Bactericidal Permeability Increasing Protein in Cystic Fibrosis

por McQuillan, Karen, Gargoum, Fatma, Murphy, Mark P., McElvaney, Oliver J., McElvaney, Noel G., Reeves, Emer P.
Publicado 2020

Alpha-1 antitrypsin for cystic fibrosis complicated by severe cytokinemic COVID-19

por McElvaney, Oliver J, O'Connor, Eoin, McEvoy, Natalie L, Fraughan, Daniel D, Clarke, Jennifer, McElvaney, Oisín F, Gunaratnam, Cedric, O'Rourke, James, Curley, Gerard F, McElvaney, Noel G
Publicado 2021

Altered Degranulation and pH of Neutrophil Phagosomes Impacts Antimicrobial Efficiency in Cystic Fibrosis

por Hayes, Elaine, Murphy, Mark P., Pohl, Kerstin, Browne, Niall, McQuillan, Karen, Saw, Le Er, Foley, Clare, Gargoum, Fatma, McElvaney, Oliver J., Hawkins, Padraig, Gunaratnam, Cedric, McElvaney, Noel G., Reeves, Emer P.
Publicado 2020

Dysregulated plasma lipid mediator profiles in critically ill COVID-19 patients

por Palmas, Francesco, Clarke, Jennifer, Colas, Romain A., Gomez, Esteban A., Keogh, Aoife, Boylan, Maria, McEvoy, Natalie, McElvaney, Oliver J., McElvaney, Oisin, Alalqam, Razi, McElvaney, Noel G., Curley, Gerard F., Dalli, Jesmond
Publicado 2021

A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19

por McElvaney, Oliver J, Hobbs, Brian D, Qiao, Dandi, McElvaney, Oisín F, Moll, Matthew, McEvoy, Natalie L, Clarke, Jennifer, O'Connor, Eoin, Walsh, Seán, Cho, Michael H, Curley, Gerard F, McElvaney, Noel G
Publicado 2020

Corrigendum to ‘A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19’

por McElvaney, Oliver J, Hobbs, Brian D, Qiao, Dandi, McElvaney, Oisín F, Moll, Matthew, McEvoy, Natalie L, Clarke, Jennifer, O'Connor, Eoin, Walsh, Sean, Cho, Michael H, Curley, Gerard F, McElvaney, Noel G
Publicado 2020

Activation of complement component 3 is associated with airways disease and pulmonary emphysema in alpha-1 antitrypsin deficiency

por O'Brien, Michael E, Fee, Laura, Browne, Niall, Carroll, Tomás P, Meleady, Paula, Henry, Michael, McQuillan, Karen, Murphy, Mark P, Logan, Mark, McCarthy, Cormac, McElvaney, Oliver J, Reeves, Emer P, McElvaney, Noel G
Publicado 2020

Neutrophil Membrane Cholesterol Content is a Key Factor in Cystic Fibrosis Lung Disease

por White, Michelle M., Geraghty, Patrick, Hayes, Elaine, Cox, Stephen, Leitch, William, Alfawaz, Bader, Lavelle, Gillian M., McElvaney, Oliver J., Flannery, Ryan, Keenan, Joanne, Meleady, Paula, Henry, Michael, Clynes, Martin, Gunaratnam, Cedric, McElvaney, Noel G., Reeves, Emer P.
Publicado 2017

Intracellular Secretory Leukoprotease Inhibitor Modulates Inositol 1,4,5-Triphosphate Generation and Exerts an Anti-Inflammatory Effect on Neutrophils of Individuals with Cystic Fi...

por Reeves, Emer P., Banville, Nessa, Ryan, Dorothy M., O'Reilly, Niamh, Bergin, David A., Pohl, Kerstin, Molloy, Kevin, McElvaney, Oliver J., Alsaleh, Khalifah, Aljorfi, Ahmed, Kandalaft, Osama, O'Flynn, Eimear, Geraghty, Patrick, O'Neill, Shane J., McElvaney, Noel G.
Publicado 2013

Prone positioning improves oxygenation and lung recruitment in patients with SARS-CoV-2 acute respiratory distress syndrome; a single centre cohort study of 20 consecutive patients

por Clarke, Jennifer, Geoghegan, Pierce, McEvoy, Natalie, Boylan, Maria, Ní Choileáin, Orna, Mulligan, Martin, Hogan, Grace, Keogh, Aoife, McElvaney, Oliver J., McElvaney, Oisín F., Bourke, John, McNicholas, Bairbre, Laffey, John G., McElvaney, Noel G., Curley, Gerard F.
Publicado 2021

A randomised, double-blind, placebo-controlled, pilot trial of intravenous plasma purified alpha-1 antitrypsin for SARS-CoV-2-induced Acute Respiratory Distress Syndrome: a structu...

por McEvoy, Natalie L., Clarke, Jennifer L., Mc Elvaney, Oliver J., Mc Elvaney, Oisin F., Boland, Fiona, Hyland, Deirdre, Geoghegan, Pierce, Donnelly, Karen, Friel, Oisin, Cullen, Ailbhe, Collins, Ann M., Fraughen, Daniel, Martin-Loeches, Ignacio, Hennessy, Martina, Laffey, John G., Mc Elvaney, Noel G., Curley, Gerard F.
Publicado 2021

Caspase-11 promotes allergic airway inflammation

por Zasłona, Zbigniew, Flis, Ewelina, Wilk, Mieszko M., Carroll, Richard G., Palsson-McDermott, Eva M., Hughes, Mark M., Diskin, Ciana, Banahan, Kathy, Ryan, Dylan G., Hooftman, Alexander, Misiak, Alicja, Kearney, Jay, Lochnit, Gunter, Bertrams, Wilhelm, Greulich, Timm, Schmeck, Bernd, McElvaney, Oliver J., Mills, Kingston H. G., Lavelle, Ed C., Wygrecka, Małgorzata, Creagh, Emma M., O’Neill, Luke A. J.
Publicado 2020

Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications

por McElvaney, Oisin F., Asakura, Takanori, Meinig, Suzanne L., Torres-Castillo, Jose L., Hagan, Robert S., Gabillard, Claudie, Murphy, Mark P., Thorne, Leigh B., Borczuk, Alain, Reeves, Emer P., Zumwalt, Ross E., Mikami, Yu, Carroll, Tomas P., Okuda, Kenichi, Hogan, Grace, McElvaney, Oliver J., Clarke, Jennifer, McEvoy, Natalie L., Mallon, Patrick W., McCarthy, Cormac, Curley, Ger, Wolfgang, Matthew C., Boucher, Richard C., McElvaney, Noel G.
Publicado 2022

A randomized, double-blind, placebo-controlled trial of intravenous alpha-1 antitrypsin for ARDS secondary to COVID-19

por McElvaney, Oliver J., McEvoy, Natalie L., Boland, Fiona, McElvaney, Oisín F., Hogan, Grace, Donnelly, Karen, Friel, Oisín, Browne, Emmet, Fraughen, Daniel D., Murphy, Mark P., Clarke, Jennifer, Choileáin, Orna Ní, O’Connor, Eoin, McGuinness, Rory, Boylan, Maria, Kelly, Alan, Hayden, John C., Collins, Ann M., Cullen, Ailbhe, Hyland, Deirdre, Carroll, Tomás P., Geoghegan, Pierce, Laffey, John G., Hennessy, Martina, Martin-Loeches, Ignacio, McElvaney, Noel G., Curley, Gerard F.
Publicado 2022

Characterization of the Inflammatory Response to Severe COVID-19 Illness

por McElvaney, Oliver J., McEvoy, Natalie L., McElvaney, Oisín F., Carroll, Tomás P., Murphy, Mark P., Dunlea, Danielle M., Ní Choileáin, Orna, Clarke, Jennifer, O’Connor, Eoin, Hogan, Grace, Ryan, Daniel, Sulaiman, Imran, Gunaratnam, Cedric, Branagan, Peter, O’Brien, Michael E., Morgan, Ross K., Costello, Richard W., Hurley, Killian, Walsh, Seán, de Barra, Eoghan, McNally, Cora, McConkey, Samuel, Boland, Fiona, Galvin, Sinead, Kiernan, Fiona, O’Rourke, James, Dwyer, Rory, Power, Michael, Geoghegan, Pierce, Larkin, Caroline, O’Leary, Ruth Aoibheann, Freeman, James, Gaffney, Alan, Marsh, Brian, Curley, Gerard F., McElvaney, Noel G.
Publicado 2020