Determination of minimal transcriptional signatures of compounds for target prediction

por Nigsch, Florian, Hutz, Janna, Cornett, Ben, Selinger, Douglas W, McAllister, Gregory, Bandyopadhyay, Somnath, Loureiro, Joseph, Jenkins, Jeremy L
Publicado 2012

DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery

por Ye, Chaoyang, Ho, Daniel J., Neri, Marilisa, Yang, Chian, Kulkarni, Tripti, Randhawa, Ranjit, Henault, Martin, Mostacci, Nadezda, Farmer, Pierre, Renner, Steffen, Ihry, Robert, Mansur, Leandra, Keller, Caroline Gubser, McAllister, Gregory, Hild, Marc, Jenkins, Jeremy, Kaykas, Ajamete
Publicado 2018

Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy

por Potting, Christoph, Crochemore, Christophe, Moretti, Francesca, Nigsch, Florian, Schmidt, Isabel, Manneville, Carole, Carbone, Walter, Knehr, Judith, DeJesus, Rowena, Lindeman, Alicia, Maher, Rob, Russ, Carsten, McAllister, Gregory, Reece-Hoyes, John S., Hoffman, Gregory R., Roma, Guglielmo, Müller, Matthias, Sailer, Andreas W., Helliwell, Stephen B.
Publicado 2018

TRRAP is a central regulator of human multiciliated cell formation

por Wang, Zhao, Plasschaert, Lindsey W., Aryal, Shivani, Renaud, Nicole A., Yang, Zinger, Choo-Wing, Rayman, Pessotti, Angelica D., Kirkpatrick, Nathaniel D., Cochran, Nadire R., Carbone, Walter, Maher, Rob, Lindeman, Alicia, Russ, Carsten, Reece-Hoyes, John, McAllister, Gregory, Hoffman, Gregory R., Roma, Guglielmo, Jaffe, Aron B.
Publicado 2018

Genome-wide CRISPR screen identifies protein pathways modulating tau protein levels in neurons

por Sanchez, Carlos G., Acker, Christopher M., Gray, Audrey, Varadarajan, Malini, Song, Cheng, Cochran, Nadire R., Paula, Steven, Lindeman, Alicia, An, Shaojian, McAllister, Gregory, Alford, John, Reece-Hoyes, John, Russ, Carsten, Craig, Lucas, Capre, Ketthsy, Doherty, Christian, Hoffman, Gregory R., Luchansky, Sarah J., Polydoro, Manuela, Dolmetsch, Ricardo, Elwood, Fiona
Publicado 2021

An iron-dependent metabolic vulnerability underlies VPS34-dependence in RKO cancer cells

por Kobylarz, Marek J., Goodwin, Jonathan M., Kang, Zhao B., Annand, John W., Hevi, Sarah, O’Mahony, Ellen, McAllister, Gregory, Reece-Hoyes, John, Wang, Qiong, Alford, John, Russ, Carsten, Lindeman, Alicia, Beibel, Martin, Roma, Guglielmo, Carbone, Walter, Knehr, Judith, Loureiro, Joseph, Antczak, Christophe, Wiederschain, Dmitri, Murphy, Leon O., Menon, Suchithra, Nyfeler, Beat
Publicado 2020

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62

por DeJesus, Rowena, Moretti, Francesca, McAllister, Gregory, Wang, Zuncai, Bergman, Phil, Liu, Shanming, Frias, Elizabeth, Alford, John, Reece-Hoyes, John S, Lindeman, Alicia, Kelliher, Jennifer, Russ, Carsten, Knehr, Judith, Carbone, Walter, Beibel, Martin, Roma, Guglielmo, Ng, Aylwin, Tallarico, John A, Porter, Jeffery A, Xavier, Ramnik J, Mickanin, Craig, Murphy, Leon O, Hoffman, Gregory R, Nyfeler, Beat
Publicado 2016

Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells

por Estoppey, David, Hewett, Jeffrey W., Guy, Chantale T., Harrington, Edmund, Thomas, Jason R., Schirle, Markus, Cuttat, Rachel, Waldt, Annick, Gerrits, Bertran, Yang, Zinger, Schuierer, Sven, Pan, Xuewen, Xie, Kevin, Carbone, Walter, Knehr, Judith, Lindeman, Alicia, Russ, Carsten, Frias, Elizabeth, Hoffman, Gregory R., Varadarajan, Malini, Ramadan, Nadire, Reece-Hoyes, John S., Wang, Qiong, Chen, Xin, McAllister, Gregory, Roma, Guglielmo, Bouwmeester, Tewis, Hoepfner, Dominic
Publicado 2017

Identification of Elongation Factor G as the Conserved Cellular Target of Argyrin B

por Nyfeler, Beat, Hoepfner, Dominic, Palestrant, Deborah, Kirby, Christina A., Whitehead, Lewis, Yu, Robert, Deng, Gejing, Caughlan, Ruth E., Woods, Angela L., Jones, Adriana K., Barnes, S. Whitney, Walker, John R., Gaulis, Swann, Hauy, Ervan, Brachmann, Saskia M., Krastel, Philipp, Studer, Christian, Riedl, Ralph, Estoppey, David, Aust, Thomas, Movva, N. Rao, Wang, Zuncai, Salcius, Michael, Michaud, Gregory A., McAllister, Gregory, Murphy, Leon O., Tallarico, John A., Wilson, Christopher J., Dean, Charles R.
Publicado 2012

TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer

por Witwicki, Robert M., Ekram, Muhammad B., Qiu, Xintao, Janiszewska, Michalina, Shu, Shaokun, Kwon, Mijung, Trinh, Anne, Frias, Elizabeth, Ramadan, Nadire, Hoffman, Greg, Yu, Kristine, Xie, Yingtian, McAllister, Gregory, McDonald, Rob, Golji, Javad, Schlabach, Michael, deWeck, Antoine, Keen, Nicholas, Chan, Ho Man, Ruddy, David, Rejtar, Tomas, Sovath, Sosathya, Silver, Serena, Sellers, William R., Jagani, Zainab, Hogarty, Michael D., Roberts, Charles, Brown, Myles, Stegmaier, Kimberly, Long, Henry, Shivdasani, Ramesh A., Pellman, David, Polyak, Kornelia
Publicado 2018