Molecular and Metabolic Mechanisms Underlying Selective 5-Aminolevulinic Acid-Induced Fluorescence in Gliomas

por Traylor, Jeffrey I., Pernik, Mark N., Sternisha, Alex C., McBrayer, Samuel K., Abdullah, Kalil G.
Publicado 2021

Integrative Gene Expression Profiling Reveals G6PD-Mediated Resistance to RNA-Directed Nucleoside Analogues in B-Cell Neoplasms

por McBrayer, Samuel K., Yarrington, Michael, Qian, Jun, Feng, Gang, Shanmugam, Mala, Gandhi, Varsha, Krett, Nancy L., Rosen, Steven T.
Publicado 2012

Protocol to establish a genetically engineered mouse model of IDH1-mutant astrocytoma

por Shi, Diana D., Lee, Joyce H., Wang, Adam C., Khanal, Januka, Gao, Wenhua, Kaelin, William G., McBrayer, Samuel K.
Publicado 2023

Preclinical modeling of lower-grade gliomas

por Tang, Lilly W., Mallela, Arka N., Deng, Hansen, Richardson, Timothy E., Hervey-Jumper, Shawn L., McBrayer, Samuel K., Abdullah, Kalil G.
Publicado 2023

Patient-Derived Cancer Organoids for Precision Oncology Treatment

por Pernik, Mark N., Bird, Cylaina E., Traylor, Jeffrey I., Shi, Diana D., Richardson, Timothy E., McBrayer, Samuel K., Abdullah, Kalil G.
Publicado 2021

Expression and phosphorylation of the AS160_v2 splice variant supports GLUT4 activation and the Warburg effect in multiple myeloma

por Cheng, Javelin C, McBrayer, Samuel K, Coarfa, Cristian, Dalva-Aydemir, Sevim, Gunaratne, Preethi H, Carpten, John D, Keats, Jonathan K, Rosen, Steven T, Shanmugam, Mala
Publicado 2013

Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Cells

por Badur, Mehmet G., Muthusamy, Thangaselvam, Parker, Seth J., Ma, Shenghong, McBrayer, Samuel K., Cordes, Thekla, Magana, Jose H., Guan, Kun-Liang, Metallo, Christian M.
Publicado 2018

Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Cells

por Badur, Mehmet G., Muthusamy, Thangaselvam, Parker, Seth J., Ma, Shenghong, McBrayer, Samuel K., Cordes, Thekla, Magana, Jose H., Guan, Kun-Liang, Metallo, Christian M.
Publicado 2018

Contemporary Mouse Models in Glioma Research

por Hicks, William H., Bird, Cylaina E., Traylor, Jeffrey I., Shi, Diana D., El Ahmadieh, Tarek Y., Richardson, Timothy E., McBrayer, Samuel K., Abdullah, Kalil G.
Publicado 2021

Chromosomal instability in adult-type diffuse gliomas

por Richardson, Timothy E., Walker, Jamie M., Abdullah, Kalil G., McBrayer, Samuel K., Viapiano, Mariano S., Mussa, Zarmeen M., Tsankova, Nadejda M., Snuderl, Matija, Hatanpaa, Kimmo J.
Publicado 2022

Isocitrate dehydrogenase mutations in gliomas: A review of current understanding and trials

por Sharma, Nikhil, Mallela, Arka N, Shi, Diana D, Tang, Lilly W, Abou-Al-Shaar, Hussam, Gersey, Zachary C, Zhang, Xiaoran, McBrayer, Samuel K, Abdullah, Kalil G
Publicado 2023

Human plasma-like medium facilitates metabolic tracing and enables upregulation of immune signaling pathways in glioblastoma explants

por El Shami, Mohamad, Savani, Milan R, Gattie, Lauren C, Smith, Bailey, Hicks, William H, Rich, Jeremy N, Richardson, Timothy E, McBrayer, Samuel K, Abdullah, Kalil G
Publicado 2023

Mismatch repair protein mutations in isocitrate dehydrogenase (IDH)-mutant astrocytoma and IDH-wild-type glioblastoma

por Richardson, Timothy E, Yokoda, Raquel T, Rashidipour, Omid, Vij, Meenakshi, Snuderl, Matija, Brem, Steven, Hatanpaa, Kimmo J, McBrayer, Samuel K, Abdullah, Kalil G, Umphlett, Melissa, Walker, Jamie M, Tsankova, Nadejda M
Publicado 2023

Global DNA methylation profiling reveals chromosomal instability in IDH-mutant astrocytomas

por Liu, Yan, Sathe, Adwait Amod, Abdullah, Kalil G., McBrayer, Samuel K., Adams, Steven H., Brenner, Andrew J., Hatanpaa, Kimmo J., Viapiano, Mariano S., Xing, Chao, Walker, Jamie M., Richardson, Timothy E.
Publicado 2022

Semi-Automated Computational Assessment of Cancer Organoid Viability Using Rapid Live-Cell Microscopy

por Buehler, Joseph D, Bird, Cylaina E, Savani, Milan R, Gattie, Lauren C, Hicks, William H, Levitt, Michael M, El Shami, Mohamad, Hatanpaa, Kimmo J, Richardson, Timothy E, McBrayer, Samuel K, Abdullah, Kalil G
Publicado 2022

DDRE-32. THERAPEUTIC TARGETING OF A NOVEL METABOLIC ADDICTION IN DIFFUSE MIDLINE GLIOMA

por Pal, Sharmistha, Kaplan, Jakub P, Stopka, Sylwia A, Regan, Michael S, Hunsel, Bradley R, Kann, Benjamin H, Agar, Nathalie Y R, Stiles, Charles D, Cooney, Tabitha M, Mueller, Sabine, Chowdhury, Dipanjan, Kaelin, William G, McBrayer, Samuel K, Haas-Kogan, Daphne
Publicado 2021

Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma

por Bajpai, Richa, Sharma, Aditi, Achreja, Abhinav, Edgar, Claudia L., Wei, Changyong, Siddiqa, Arusha A., Gupta, Vikas A., Matulis, Shannon M., McBrayer, Samuel K., Mittal, Anjali, Rupji, Manali, Barwick, Benjamin G., Lonial, Sagar, Nooka, Ajay K., Boise, Lawrence H., Nagrath, Deepak, Shanmugam, Mala
Publicado 2020

DDRE-29. DE NOVO PYRIMIDINE SYNTHESIS IS A TARGETABLE VULNERABILITY IN IDH-MUTANT GLIOMA

por Shi, Diana D, Wang, Adam C, Levitt, Michael M, Endress, Jennifer E, Xu, Min, Gao, Wenhua, Khanal, Januka, Bonal, Dennis, Kornblum, Harley I, Nguyen, Quang-De, Gradl, Stefan, Sutter, Andreas, Jeffers, Michael, Janzer, Andreas, Cahill, Daniel P, Ligon, Keith L, Abdullah, Kalil G, Harris, Isaac S, Kaelin, William G, McBrayer, Samuel K
Publicado 2021

Establishment of patient-derived organoid models of lower-grade glioma

por Abdullah, Kalil G, Bird, Cylaina E, Buehler, Joseph D, Gattie, Lauren C, Savani, Milan R, Sternisha, Alex C, Xiao, Yi, Levitt, Michael M, Hicks, William H, Li, Wenhao, Ramirez, Denise M O, Patel, Toral, Garzon-Muvdi, Tomas, Barnett, Samuel, Zhang, Gao, Ashley, David M, Hatanpaa, Kimmo J, Richardson, Timothy E, McBrayer, Samuel K
Publicado 2021

GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis

por Kremer, Daniel M., Nelson, Barbara S., Lin, Lin, Yarosz, Emily L., Halbrook, Christopher J., Kerk, Samuel A., Sajjakulnukit, Peter, Myers, Amy, Thurston, Galloway, Hou, Sean W., Carpenter, Eileen S., Andren, Anthony C., Nwosu, Zeribe C., Cusmano, Nicholas, Wisner, Stephanie, Mbah, Nneka E., Shan, Mengrou, Das, Nupur K., Magnuson, Brian, Little, Andrew C., Savani, Milan R., Ramos, Johanna, Gao, Tina, Sastra, Stephen A., Palermo, Carmine F., Badgley, Michael A., Zhang, Li, Asara, John M., McBrayer, Samuel K., di Magliano, Marina Pasca, Crawford, Howard C., Shah, Yatrik M., Olive, Kenneth P., Lyssiotis, Costas A.
Publicado 2021