In silico Mapping of Protein Unfolding Mutations for Inherited Disease

por McCafferty, Caitlyn L., Sergeev, Yuri V.
Publicado 2016

Dataset of eye disease-related proteins analyzed using the unfolding mutation screen

por McCafferty, Caitlyn L., Sergeev, Yuri V.
Publicado 2016

Global computational mutagenesis provides a critical stability framework in protein structures

por McCafferty, Caitlyn L., Sergeev, Yuri V.
Publicado 2017

Correction: Global computational mutagenesis provides a critical stability framework in protein structures

por McCafferty, Caitlyn L., Sergeev, Yuri V.
Publicado 2018

Simplified geometric representations of protein structures identify complementary interaction interfaces

por McCafferty, Caitlyn L., Marcotte, Edward M., Taylor, David W.
Publicado 2020

Improving integrative 3D modeling into low‐ to medium‐resolution electron microscopy structures with evolutionary couplings

por McCafferty, Caitlyn L., Taylor, David W., Marcotte, Edward M.
Publicado 2021

Structural Biology in the Multi-Omics Era

por McCafferty, Caitlyn L., Verbeke, Eric J., Marcotte, Edward M., Taylor, David W.
Publicado 2020

Does AlphaFold2 model proteins’ intracellular conformations? An experimental test using cross-linking mass spectrometry of endogenous ciliary proteins

por McCafferty, Caitlyn L., Pennington, Erin L., Papoulas, Ophelia, Taylor, David W., Marcotte, Edward M.
Publicado 2023

An amino acid-resolution interactome for motile cilia illuminates the structure and function of ciliopathy protein complexes

por McCafferty, Caitlyn L., Papoulas, Ophelia, Lee, Chanjae, Bui, Khanh Huy, Taylor, David W., Marcotte, Edward M., Wallingford, John B.
Publicado 2023

Integrative modeling reveals the molecular architecture of the intraflagellar transport A (IFT-A) complex

por McCafferty, Caitlyn L, Papoulas, Ophelia, Jordan, Mareike A, Hoogerbrugge, Gabriel, Nichols, Candice, Pigino, Gaia, Taylor, David W, Wallingford, John B, Marcotte, Edward M
Publicado 2022

Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism

por Ghanaeian, Avrin, Majhi, Sumita, McCafferty, Caitlyn L., Nami, Babak, Black, Corbin S., Yang, Shun Kai, Legal, Thibault, Papoulas, Ophelia, Janowska, Martyna, Valente-Paterno, Melissa, Marcotte, Edward M., Wloga, Dorota, Bui, Khanh Huy
Publicado 2023

Type III CRISPR-Cas complexes act as protein-assisted ribozymes during target RNA cleavage

por Schwartz, Evan A., Bravo, Jack P.K., Ahsan, Mohd, Macias, Luis A., McCafferty, Caitlyn L., Dangerfield, Tyler L., Walker, Jada N., Brodbelt, Jennifer S., Palermo, Giulia, Fineran, Peter C., Fagerlund, Robert D., Taylor, David W.
Publicado 2023

Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins

por Kubo, Shintaroh, Black, Corbin S., Joachimiak, Ewa, Yang, Shun Kai, Legal, Thibault, Peri, Katya, Khalifa, Ahmad Abdelzaher Zaki, Ghanaeian, Avrin, McCafferty, Caitlyn L., Valente-Paterno, Melissa, De Bellis, Chelsea, Huynh, Phuong M., Fan, Zhe, Marcotte, Edward M., Wloga, Dorota, Bui, Khanh Huy
Publicado 2023