Slow and steady wins the race: Optimizing lentiviral vector production for efficient clinical-scale manufacturing

por McCarron, Alexandra
Publicado 2023

Airway disease phenotypes in animal models of cystic fibrosis

por McCarron, Alexandra, Donnelley, Martin, Parsons, David
Publicado 2018

Effective viral-mediated lung gene therapy: is airway surface preparation necessary?

por McCarron, Alexandra, Cmielewski, Patricia, Drysdale, Victoria, Parsons, David, Donnelley, Martin
Publicado 2022

Particle coating alters mucociliary transit in excised rat trachea: A synchrotron X-ray imaging study

por Gardner, Mark, McCarron, Alexandra, Morgan, Kaye, Parsons, David, Donnelley, Martin
Publicado 2019

To bead or not to bead: A review of Pseudomonas aeruginosa lung infection models for cystic fibrosis

por Reyne, Nicole, McCarron, Alexandra, Cmielewski, Patricia, Parsons, David, Donnelley, Martin
Publicado 2023

Large-scale production of lentiviral vectors using multilayer cell factories

por Rout-Pitt, Nathan, McCarron, Alexandra, McIntyre, Chantelle, Parsons, David, Donnelley, Martin
Publicado 2018

Breaching the Delivery Barrier: Chemical and Physical Airway Epithelium Disruption Strategies for Enhancing Lentiviral-Mediated Gene Therapy

por McCarron, Alexandra, Farrow, Nigel, Cmielewski, Patricia, Knight, Emma, Donnelley, Martin, Parsons, David
Publicado 2021

Single-Dose Lentiviral Mediated Gene Therapy Recovers CFTR Function in Cystic Fibrosis Knockout Rats

por Reyne, Nicole, Cmielewski, Patricia, McCarron, Alexandra, Delhove, Juliette, Parsons, David, Donnelley, Martin
Publicado 2021

Essential Fatty Acid Deficiency in Cystic Fibrosis Disease Progression: Role of Genotype and Sex

por Shrestha, Nirajan, McCarron, Alexandra, Rout-Pitt, Nathan, Donnelley, Martin, Parsons, David W., Hryciw, Deanne H.
Publicado 2022

Repeat or single-dose lentiviral vector administration to mouse lungs? It’s all about the timing

por Donnelley, Martin, Cmielewski, Patricia, Knight, Emma, Carpentieri, Chantelle, McCarron, Alexandra, Rout-Pitt, Nathan, Parsons, David, Farrow, Nigel
Publicado 2023

Changes in Essential Fatty Acids and Ileal Genes Associated with Metabolizing Enzymes and Fatty Acid Transporters in Rodent Models of Cystic Fibrosis

por Shrestha, Nirajan, Rout-Pitt, Nathan, McCarron, Alexandra, Jackson, Courtney A., Bulmer, Andrew C., McAinch, Andrew J., Donnelley, Martin, Parsons, David W., Hryciw, Deanne H.
Publicado 2023

Improved in-vivo airway gene transfer via magnetic-guidance, with protocol development informed by synchrotron imaging

por Donnelley, Martin, Cmielewski, Patricia, Morgan, Kaye, Delhove, Juliette, Reyne, Nicole, McCarron, Alexandra, Rout-Pitt, Nathan, Drysdale, Victoria, Carpentieri, Chantelle, Spiers, Kathryn, Takeuchi, Akihisa, Uesugi, Kentaro, Yagi, Naoto, Parsons, David
Publicado 2022

Methods for dynamic synchrotron X-ray respiratory imaging in live animals

por Morgan, Kaye Susannah, Parsons, David, Cmielewski, Patricia, McCarron, Alexandra, Gradl, Regine, Farrow, Nigel, Siu, Karen, Takeuchi, Akihisa, Suzuki, Yoshio, Uesugi, Kentaro, Uesugi, Masayuki, Yagi, Naoto, Hall, Chris, Klein, Mitzi, Maksimenko, Anton, Stevenson, Andrew, Hausermann, Daniel, Dierolf, Martin, Pfeiffer, Franz, Donnelley, Martin
Publicado 2020