Multisite rate control analysis identifies ribosomal scanning as the sole high‐capacity/low‐flux‐control step in mRNA translation

por Firczuk, Helena, Teahan, James, Mendes, Pedro, McCarthy, John E.G.
Publicado 2019

Translation initiation events on structured eukaryotic mRNAs generate gene expression noise

por Dacheux, Estelle, Malys, Naglis, Meng, Xiang, Ramachandran, Vinoy, Mendes, Pedro, McCarthy, John EG
Publicado 2017

Minimum-noise production of translation factor eIF4G maps to a mechanistically determined optimal rate control window for protein synthesis

por Meng, Xiang, Firczuk, Helena, Pietroni, Paola, Westbrook, Richard, Dacheux, Estelle, Mendes, Pedro, McCarthy, John E.G.
Publicado 2017

An in vivo control map for the eukaryotic mRNA translation machinery

por Firczuk, Helena, Kannambath, Shichina, Pahle, Jürgen, Claydon, Amy, Beynon, Robert, Duncan, John, Westerhoff, Hans, Mendes, Pedro, McCarthy, John EG
Publicado 2013

Identifying eIF4E-binding protein translationally-controlled transcripts reveals links to mRNAs bound by specific PUF proteins

por Cridge, Andrew G., Castelli, Lydia M., Smirnova, Julia B., Selley, Julian N., Rowe, William, Hubbard, Simon J., McCarthy, John E.G., Ashe, Mark P., Grant, Christopher M., Pavitt, Graham D.
Publicado 2010

A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes

por Smallbone, Kieran, Messiha, Hanan L., Carroll, Kathleen M., Winder, Catherine L., Malys, Naglis, Dunn, Warwick B., Murabito, Ettore, Swainston, Neil, Dada, Joseph O., Khan, Farid, Pir, Pınar, Simeonidis, Evangelos, Spasić, Irena, Wishart, Jill, Weichart, Dieter, Hayes, Neil W., Jameson, Daniel, Broomhead, David S., Oliver, Stephen G., Gaskell, Simon J., McCarthy, John E.G., Paton, Norman W., Westerhoff, Hans V., Kell, Douglas B., Mendes, Pedro
Publicado 2013