Fitting Gaussian mixture models on incomplete data

por McCaw, Zachary R., Aschard, Hugues, Julienne, Hanna
Publicado 2022

Correction: Fitting Gaussian mixture models on incomplete data

por McCaw, Zachary R., Aschard, Hugues, Julienne, Hanna
Publicado 2022

Pitfall in the Design and Analysis of Comparative Oncology Trials With a Time-to-Event Endpoint and Recommendations

por McCaw, Zachary R, Kim, Dae Hyun, Wei, Lee-Jen
Publicado 2022

Sample size calculation for randomized selection trials with a time‐to‐event endpoint and a margin of practical equivalence

por Dehbi, Hakim‐Moulay, Embleton‐Thirsk, Andrew, McCaw, Zachary Ryan
Publicado 2022

Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice

por Verhein, Kirsten C., McCaw, Zachary, Gladwell, Wesley, Trivedi, Shweta, Bushel, Pierre R., Kleeberger, Steven R.
Publicado 2015

Moving beyond conventional stratified analysis to assess the treatment effect in a comparative oncology study

por Sun, Ryan, McCaw, Zachary, Tian, Lu, Uno, Hajime, Hong, Fangxin, Kim, Dae Hyun, Wei, Lee-Jen
Publicado 2021

Assessment of Median and Mean Survival Time in Cancer Clinical Trials

por Das, Ananya, Lin, Timothy A., Lin, Christine, Meirson, Tomer, McCaw, Zachary R., Tian, Lu, Ludmir, Ethan B.
Publicado 2023

Selecting appropriate endpoints for assessing treatment effects in comparative clinical studies for COVID-19

por McCaw, Zachary R., Tian, Lu, Sheth, Kevin N., Hsu, Wan-Ting, Kimberly, W. Taylor, Wei, Lee-Jen
Publicado 2020

Using a Clinically Interpretable End Point Composed of Multiple Outcomes to Evaluate Totality of Treatment Effect in Comparative Oncology Studies

por Wang, Xiaofei, McCaw, Zachary R., Tian, Lu, Stinchcombe, Thomas E., Vokes, Everett, Ludmir, Ethan B., Wei, Lee-Jen
Publicado 2023

DeepNull models non-linear covariate effects to improve phenotypic prediction and association power

por McCaw, Zachary R., Colthurst, Thomas, Yun, Taedong, Furlotte, Nicholas A., Carroll, Andrew, Alipanahi, Babak, McLean, Cory Y., Hormozdiari, Farhad
Publicado 2022

An allelic-series rare-variant association test for candidate-gene discovery

por McCaw, Zachary R., O’Dushlaine, Colm, Somineni, Hari, Bereket, Michael, Klein, Christoph, Karaletsos, Theofanis, Casale, Francesco Paolo, Koller, Daphne, Soare, Thomas W.
Publicado 2023

Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells

por Kleinstiver, Benjamin P., Tsai, Shengdar Q., Prew, Michelle S., Nguyen, Nhu T., Welch, Moira M., Lopez, Jose M., McCaw, Zachary R., Aryee, Martin J., Joung, J. Keith
Publicado 2016

Large-scale machine-learning-based phenotyping significantly improves genomic discovery for optic nerve head morphology

por Alipanahi, Babak, Hormozdiari, Farhad, Behsaz, Babak, Cosentino, Justin, McCaw, Zachary R., Schorsch, Emanuel, Sculley, D., Dorfman, Elizabeth H., Foster, Paul J., Peng, Lily H., Phene, Sonia, Hammel, Naama, Carroll, Andrew, Khawaja, Anthony P., McLean, Cory Y.
Publicado 2021

Multitrait GWAS to connect disease variants and biological mechanisms

por Julienne, Hanna, Laville, Vincent, McCaw, Zachary R., He, Zihuai, Guillemot, Vincent, Lasry, Carla, Ziyatdinov, Andrey, Nerin, Cyril, Vaysse, Amaury, Lechat, Pierre, Ménager, Hervé, Le Goff, Wilfried, Dube, Marie-Pierre, Kraft, Peter, Ionita-Laza, Iuliana, Vilhjálmsson, Bjarni J., Aschard, Hugues
Publicado 2021

Unsupervised representation learning improves genomic discovery and risk prediction for respiratory and circulatory functions and diseases

por Yun, Taedong, Cosentino, Justin, Behsaz, Babak, McCaw, Zachary R., Hill, Davin, Luben, Robert, Lai, Dongbing, Bates, John, Yang, Howard, Schwantes-An, Tae-Hwi, Zhou, Yuchen, Khawaja, Anthony P., Carroll, Andrew, Hobbs, Brian D., Cho, Michael H., McLean, Cory Y., Hormozdiari, Farhad
Publicado 2023

Effect of Dapagliflozin on Total Heart Failure Events in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Prespecified Analysis of the DELIVER Tria...

por Jhund, Pardeep S., Claggett, Brian L., Talebi, Atefeh, Butt, Jawad H., Gasparyan, Samvel B., Wei, Lee-Jen, McCaw, Zachary R., Wilderäng, Ulrica, Bengtsson, Olof, Desai, Akshay S., Petersson, Magnus, Langkilde, Anna Maria, de Boer, Rudolf A., Hernandez, Adrian F., Inzucchi, Silvio E., Kosiborod, Mikhail N., Lam, Carolyn S. P., Martinez, Felipe A., Shah, Sanjiv J., Vaduganathan, Muthiah, Solomon, Scott D., McMurray, John J. V.
Publicado 2023

A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies

por Li, Xihao, Chen, Han, Selvaraj, Margaret Sunitha, Van Buren, Eric, Zhou, Hufeng, Wang, Yuxuan, Sun, Ryan, McCaw, Zachary R., Yu, Zhi, Arnett, Donna K., Bis, Joshua C., Blangero, John, Boerwinkle, Eric, Bowden, Donald W., Brody, Jennifer A., Cade, Brian E., Carson, April P., Carlson, Jenna C., Chami, Nathalie, Chen, Yii-Der Ida, Curran, Joanne E., de Vries, Paul S., Fornage, Myriam, Franceschini, Nora, Freedman, Barry I., Gu, Charles, Heard-Costa, Nancy L., He, Jiang, Hou, Lifang, Hung, Yi-Jen, Irvin, Marguerite R., Kaplan, Robert C., Kardia, Sharon L.R., Kelly, Tanika, Konigsberg, Iain, Kooperberg, Charles, Kral, Brian G., Li, Changwei, Loos, Ruth J.F., Mahaney, Michael C., Martin, Lisa W., Mathias, Rasika A., Minster, Ryan L., Mitchell, Braxton D., Montasser, May E., Morrison, Alanna C., Palmer, Nicholette D., Peyser, Patricia A., Psaty, Bruce M., Raffield, Laura M., Redline, Susan, Reiner, Alexander P., Rich, Stephen S., Sitlani, Colleen M., Smith, Jennifer A., Taylor, Kent D., Tiwari, Hemant, Vasan, Ramachandran S., Wang, Zhe, Yanek, Lisa R., Yu, Bing, Rice, Kenneth M., Rotter, Jerome I., Peloso, Gina M., Natarajan, Pradeep, Li, Zilin, Liu, Zhonghua, Lin, Xihong
Publicado 2023