Partial inhibition of Cdk1 in G(2) phase overrides the SAC and decouples mitotic events

por McCloy, Rachael A, Rogers, Samuel, Caldon, C Elizabeth, Lorca, Thierry, Castro, Anna, Burgess, Andrew
Publicado 2014

The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia

por Shearer, Robert F., Frikstad, Kari-Anne Myrum, McKenna, Jessie, McCloy, Rachael A., Deng, Niantao, Burgess, Andrew, Stokke, Trond, Patzke, Sebastian, Saunders, Darren N.
Publicado 2018

Dataset from the global phosphoproteomic mapping of early mitotic exit in human cells

por Rogers, Samuel, McCloy, Rachael A., Parker, Benjamin L., Chaudhuri, Rima, Gayevskiy, Velimir, Hoffman, Nolan J., Watkins, D. Neil, Daly, Roger J., James, David E., Burgess, Andrew
Publicado 2015

Tamoxifen-Induced Epigenetic Silencing of Oestrogen-Regulated Genes in Anti-Hormone Resistant Breast Cancer

por Stone, Andrew, Valdés-Mora, Fatima, Gee, Julia M. W., Farrow, Lynne, McClelland, Richard A., Fiegl, Heidi, Dutkowski, Carol, McCloy, Rachael A., Sutherland, Robert L., Musgrove, Elizabeth A., Nicholson, Robert I.
Publicado 2012

PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells

por Rogers, Samuel, Fey, Dirk, McCloy, Rachael A., Parker, Benjamin L., Mitchell, Nicholas J., Payne, Richard J., Daly, Roger J., James, David E., Caldon, C. Elizabeth, Watkins, D. Neil, Croucher, David R., Burgess, Andrew
Publicado 2016

The Role of Canonical and Non-Canonical Hedgehog Signaling in Tumor Progression in a Mouse Model of Small Cell Lung Cancer

por Szczepny, Anette, Rogers, Samuel, Jayasekara, W. Samantha N., Park, Kwon, McCloy, Rachael A., Cochrane, Catherine R., Ganju, Vinod, Cooper, Wendy A., Sage, Julien, Peacock, Craig D., Cain, Jason E., Burgess, Andrew, Watkins, D. Neil
Publicado 2017

Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma

por Hastings, Jordan F, Gonzalez Rajal, Alvaro, Latham, Sharissa L, Han, Jeremy ZR, McCloy, Rachael A, O'Donnell, Yolande EI, Phimmachanh, Monica, Murphy, Alexander D, Nagrial, Adnan, Daneshvar, Dariush, Chin, Venessa, Watkins, D Neil, Burgess, Andrew, Croucher, David R
Publicado 2020

A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma

por Gonzalez Rajal, Alvaro, Marzec, Kamila A, McCloy, Rachael A, Nobis, Max, Chin, Venessa, Hastings, Jordan F, Lai, Kaitao, Kennerson, Marina, Hughes, William E, Vaghjiani, Vijesh, Timpson, Paul, Cain, Jason E, Watkins, D Neil, Croucher, David R, Burgess, Andrew
Publicado 2021

The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53

por Szczepny, Anette, Carey, Kirstyn, McKenzie, Lisa, Jayasekara, W. Samantha N., Rossello, Fernando, Gonzalez-Rajal, Alvaro, McCaw, Andrew S., Popovski, Dean, Wang, Die, Sadler, Anthony J., Mahar, Annabelle, Russell, Prudence A., Wright, Gavin, McCloy, Rachael A., Garama, Daniel J., Gough, Daniel J., Baylin, Stephen B., Burgess, Andrew, Cain, Jason E., Watkins, D. Neil
Publicado 2018

MASTL overexpression promotes chromosome instability and metastasis in breast cancer

por Rogers, Samuel, McCloy, Rachael A., Parker, Benjamin L., Gallego-Ortega, David, Law, Andrew M. K., Chin, Venessa T., Conway, James R. W., Fey, Dirk, Millar, Ewan K. A., O’Toole, Sandra, Deng, Niantao, Swarbrick, Alexander, Chastain, Paul D., Cesare, Anthony J., Timpson, Paul, Caldon, C. Elizabeth, Croucher, David R., James, David E., Watkins, D. Neil, Burgess, Andrew
Publicado 2018

Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma

por Daniszewski, Maciej, Senabouth, Anne, Liang, Helena H., Han, Xikun, Lidgerwood, Grace E., Hernández, Damián, Sivakumaran, Priyadharshini, Clarke, Jordan E., Lim, Shiang Y., Lees, Jarmon G., Rooney, Louise, Gulluyan, Lerna, Souzeau, Emmanuelle, Graham, Stuart L., Chan, Chia-Ling, Nguyen, Uyen, Farbehi, Nona, Gnanasambandapillai, Vikkitharan, McCloy, Rachael A., Clarke, Linda, Kearns, Lisa S., Mackey, David A., Craig, Jamie E., MacGregor, Stuart, Powell, Joseph E., Pébay, Alice, Hewitt, Alex W.
Publicado 2022

Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer

por Leong, Tracy L., Gayevskiy, Velimir, Steinfort, Daniel P., De Massy, Marc R., Gonzalez-Rajal, Alvaro, Marini, Kieren D., Stone, Emily, Chin, Venessa, Havryk, Adrian, Plit, Marshall, Irving, Louis B., Jennings, Barton R., McCloy, Rachael A., Jayasekara, W. Samantha N., Alamgeer, Muhammad, Boolell, Vishal, Field, Andrew, Russell, Prudence A., Kumar, Beena, Gough, Daniel J., Szczepny, Anette, Ganju, Vinod, Rossello, Fernando J., Cain, Jason E., Papenfuss, Anthony T., Asselin-Labat, Marie-Liesse, Cowley, Mark J., Watkins, D. Neil
Publicado 2018

Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration

por Senabouth, Anne, Daniszewski, Maciej, Lidgerwood, Grace E., Liang, Helena H., Hernández, Damián, Mirzaei, Mehdi, Keenan, Stacey N., Zhang, Ran, Han, Xikun, Neavin, Drew, Rooney, Louise, Lopez Sanchez, Maria Isabel G., Gulluyan, Lerna, Paulo, Joao A., Clarke, Linda, Kearns, Lisa S., Gnanasambandapillai, Vikkitharan, Chan, Chia-Ling, Nguyen, Uyen, Steinmann, Angela M., McCloy, Rachael A., Farbehi, Nona, Gupta, Vivek K., Mackey, David A., Bylsma, Guy, Verma, Nitin, MacGregor, Stuart, Watt, Matthew J., Guymer, Robyn H., Powell, Joseph E., Hewitt, Alex W., Pébay, Alice
Publicado 2022