Editorial: Diabetes and non-alcoholic fatty liver disease: points of physiological and mechanistic intersection and current co-therapeutic approaches

por Giannoukakis, Nick, McCommis, Kyle S.
Publicado 2023

Treating Hepatic Steatosis and Fibrosis by Modulating Mitochondrial Pyruvate Metabolism

por McCommis, Kyle S., Finck, Brian N.
Publicado 2018

The Hepatic Mitochondrial Pyruvate Carrier as a Regulator of Systemic Metabolism and a Therapeutic Target for Treating Metabolic Disease

por McCommis, Kyle S., Finck, Brian N.
Publicado 2023

Two Faces of Pioglitazone: Sorting Out the Roles of its PPARγ Binding Versus Mitochondrial Pyruvate Carrier Inhibition Is Not So Simple

por Yuan, Liyun, McCommis, Kyle S., Neuschwander‐Tetri, Brent A.
Publicado 2021

Cardiac‐specific Hexokinase 2 Overexpression Attenuates Hypertrophy by Increasing Pentose Phosphate Pathway Flux

por McCommis, Kyle S., Douglas, Diana L., Krenz, Maike, Baines, Christopher P.
Publicado 2013

Treating fatty liver disease by modulating mitochondrial pyruvate metabolism

por Colca, Jerry R., McDonald, William G., McCommis, Kyle S., Finck, Brian N.
Publicado 2017

Myeloperoxidase-derived hypochlorous acid targets human airway epithelial plasmalogens liberating protein modifying electrophilic 2-chlorofatty aldehydes

por Shakya, Shubha, Pyles, Kelly D., Albert, Carolyn J., Patel, Rakesh P., McCommis, Kyle S., Ford, David A.
Publicado 2022

Resting myocardial perfusion quantification with CMR arterial spin labeling at 1.5 T and 3.0 T

por Northrup, Benjamin E, McCommis, Kyle S, Zhang, Haosen, Ray, Shuddhadeb, Woodard, Pamela K, Gropler, Robert J, Zheng, Jie
Publicado 2008

Quantification of global myocardial oxygenation in humans: initial experience

por McCommis, Kyle S, O'Connor, Robert, Lesniak, Donna, Lyons, Matt, Woodard, Pamela K, Gropler, Robert J, Zheng, Jie
Publicado 2010

Novel insulin sensitizer MSDC-0602K improves insulinemia and fatty liver disease in mice, alone and in combination with liraglutide

por Kamm, Dakota R., Pyles, Kelly D., Sharpe, Martin C., Healy, Laura N., Colca, Jerry R., McCommis, Kyle S.
Publicado 2021

An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretion

por McCommis, Kyle S., Hodges, Wesley T., Bricker, Daniel K., Wisidagama, Dona R., Compan, Vincent, Remedi, Maria S., Thummel, Carl S., Finck, Brian N.
Publicado 2016

Identification of Novel Mitochondrial Pyruvate Carrier Inhibitors by Homology Modeling and Pharmacophore-Based Virtual Screening

por Hegazy, Lamees, Gill, Lauren E., Pyles, Kelly D., Kaiho, Christopher, Kchouk, Sophia, Finck, Brian N., McCommis, Kyle S., Elgendy, Bahaa
Publicado 2022

NADPH and Glutathione Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis

por Gansemer, Erica R., McCommis, Kyle S., Martino, Michael, King-McAlpin, Abdul Qaadir, Potthoff, Matthew J., Finck, Brian N., Taylor, Eric B., Rutkowski, D. Thomas
Publicado 2020

NADPH and Glutathione Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis

por Gansemer, Erica R., McCommis, Kyle S., Martino, Michael, King-McAlpin, Abdul Qaadir, Potthoff, Matthew J., Finck, Brian N., Taylor, Eric B., Rutkowski, D. Thomas
Publicado 2022

Abrogating Monoacylglycerol Acyltransferase Activity in Liver Improves Glucose Tolerance and Hepatic Insulin Signaling in Obese Mice

por Hall, Angela M., Soufi, Nisreen, Chambers, Kari T., Chen, Zhouji, Schweitzer, George G., McCommis, Kyle S., Erion, Derek M., Graham, Mark J., Su, Xiong, Finck, Brian N.
Publicado 2014

Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations

por Chambers, Kari T., Cooper, Michael A., Swearingen, Alison R., Brookheart, Rita T., Schweitzer, George G., Weinheimer, Carla J., Kovacs, Attila, Koves, Timothy R., Muoio, Deborah M., McCommis, Kyle S., Finck, Brian N.
Publicado 2021

A new twist on an old idea part 2: cyclosporine preserves normal mitochondrial but not cardiomyocyte function in mini‐swine with compensated heart failure

por Hiemstra, Jessica A., Gutiérrez‐Aguilar, Manuel, Marshall, Kurt D., McCommis, Kyle S., Zgoda, Pamela J., Cruz‐Rivera, Noelany, Jenkins, Nathan T., Krenz, Maike, Domeier, Timothy L., Baines, Christopher P., Emter, Craig A.
Publicado 2014

Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice

por Hodges, Wesley T., Jarasvaraparn, Chaowapong, Ferguson, Daniel, Griffett, Kristine, Gill, Lauren E., Chen, Yana, Ilagan, Ma. Xenia G., Hegazy, Lamees, Elgendy, Bahaa, Cho, Kevin, Patti, Gary J., McCommis, Kyle S., Finck, Brian N.
Publicado 2021

Enhancing Hepatic MBOAT7 Expression in Mice With Nonalcoholic Steatohepatitis

por Sharpe, Martin C., Pyles, Kelly D., Hallcox, Taylor, Kamm, Dakota R., Piechowski, Michaela, Fisk, Bryan, Albert, Carolyn J., Carpenter, Danielle H., Ulmasov, Barbara, Ford, David A., Neuschwander-Tetri, Brent A., McCommis, Kyle S.
Publicado 2023

Pleiotropic actions of IP6K1 mediate hepatic metabolic dysfunction to promote nonalcoholic fatty liver disease and steatohepatitis

por Mukherjee, Sandip, Chakraborty, Molee, Ulmasov, Barbara, McCommis, Kyle, Zhang, Jinsong, Carpenter, Danielle, Msengi, Eliwaza Naomi, Haubner, Jake, Guo, Chun, Pike, Daniel P., Ghoshal, Sarbani, Ford, David A., Neuschwander-Tetri, Brent A., Chakraborty, Anutosh
Publicado 2021