ULK4 and Fused/STK36 interact to mediate assembly of a motile flagellum

por McCoy, Ciaran J., Paupelin-Vaucelle, Humbeline, Gorilak, Peter, Beneke, Tom, Varga, Vladimir, Gluenz, Eva
Publicado 2023

Human Leukocytes Kill Brugia malayi Microfilariae Independently of DNA-Based Extracellular Trap Release

por McCoy, Ciaran J., Reaves, Barbara J., Giguère, Steeve, Coates, Ruby, Rada, Balázs, Wolstenholme, Adrian J.
Publicado 2017

Recognition and killing of Brugia malayi microfilariae by human immune cells is dependent on the parasite sample and is not altered by ivermectin treatment

por Reaves, Barbara J., Wallis, Connor, McCoy, Ciaran J., Lorenz, W. Walter, Rada, Balazs, Wolstenholme, Adrian J.
Publicado 2018

Unraveling flp-11/flp-32 dichotomy in nematodes

por Atkinson, Louise E., Miskelly, Iain R., Moffett, Christy L., McCoy, Ciaran J., Maule, Aaron G., Marks, Nikki J., Mousley, Angela
Publicado 2016

In silico analyses of neuropeptide-like protein (NLP) profiles in parasitic nematodes

por McKay, Fiona M., McCoy, Ciaran J., Crooks, Bethany, Marks, Nikki J., Maule, Aaron G., Atkinson, Louise E., Mousley, Angela
Publicado 2022

Novel integrated computational AMP discovery approaches highlight diversity in the helminth AMP repertoire

por Irvine, Allister, McKenzie, Darrin, McCoy, Ciaran J., Graham, Robert L. J., Graham, Ciaren, Huws, Sharon A., Atkinson, Louise E., Mousley, Angela
Publicado 2023

Pharmacological profile of Ascaris suum ACR‐16, a new homomeric nicotinic acetylcholine receptor widely distributed in Ascaris tissues

por Abongwa, Melanie, Buxton, Samuel K, Courtot, Elise, Charvet, Claude L, Neveu, Cédric, McCoy, Ciaran J, Verma, Saurabh, Robertson, Alan P, Martin, Richard J
Publicado 2016

New insights into the FLPergic complements of parasitic nematodes: Informing deorphanisation approaches

por McCoy, Ciaran J., Atkinson, Louise E., Zamanian, Mostafa, McVeigh, Paul, Day, Tim A., Kimber, Michael J., Marks, Nikki J., Maule, Aaron G., Mousley, Angela
Publicado 2014

RNA interference in adult Ascaris suum – an opportunity for the development of a functional genomics platform that supports organism-, tissue- and cell-based biology in a nematode...

por McCoy, Ciaran J., Warnock, Neil D., Atkinson, Louise E., Atcheson, Erwan, Martin, Richard J., Robertson, Alan P., Maule, Aaron G., Marks, Nikki J., Mousley, Angela
Publicado 2015

Pan-phylum In Silico Analyses of Nematode Endocannabinoid Signalling Systems Highlight Novel Opportunities for Parasite Drug Target Discovery

por Crooks, Bethany A., Mckenzie, Darrin, Cadd, Luke C., McCoy, Ciaran J., McVeigh, Paul, Marks, Nikki J., Maule, Aaron G., Mousley, Angela, Atkinson, Louise E.
Publicado 2022

flp-32 Ligand/Receptor Silencing Phenocopy Faster Plant Pathogenic Nematodes

por Atkinson, Louise E., Stevenson, Michael, McCoy, Ciaran J., Marks, Nikki J., Fleming, Colin, Zamanian, Mostafa, Day, Tim A., Kimber, Michael J., Maule, Aaron G., Mousley, Angela
Publicado 2013

Evaluation of changes in drug susceptibility and population genetic structure in Haemonchus contortus following worm replacement as a means to reverse the impact of multiple-anthel...

por George, Melissa M., Vatta, Adriano F., Howell, Sue B., Storey, Bob E., McCoy, Ciaran J., Wolstenholme, Adrian J., Redman, Elizabeth M., Gilleard, John S., Kaplan, Ray M.
Publicado 2021

EAT-18 is an essential auxiliary protein interacting with the non-alpha nAChR subunit EAT-2 to form a functional receptor

por Choudhary, Shivani, Buxton, Samuel K., Puttachary, Sreekanth, Verma, Saurabh, Mair, Gunnar R., McCoy, Ciaran J., Reaves, Barbara J., Wolstenholme, Adrian J., Martin, Richard J., Robertson, Alan P.
Publicado 2020

Phylum-Spanning Neuropeptide GPCR Identification and Prioritization: Shaping Drug Target Discovery Pipelines for Nematode Parasite Control

por Atkinson, Louise E., McCoy, Ciaran J., Crooks, Bethany A., McKay, Fiona M., McVeigh, Paul, McKenzie, Darrin, Irvine, Allister, Harrington, John, Rosa, Bruce A., Mitreva, Makedonka, Marks, Nikki J., Maule, Aaron G., Mousley, Angela
Publicado 2021