Developing a mechanistic understanding of the nonlinear pharmacokinetics of letermovir and prospective drug interaction with everolimus using physiological‐based pharmacokinetic mo...

por Menzel, Karsten, Kuo, Yuhsin, Chen, Dapeng, Hartmann, Georgy, Wang, Ying‐Hong, Cho, Carolyn R., McCrea, Jacqueline B., Asari, Kazuhiko
Publicado 2023

Assessment of Pharmacokinetic Interaction Between Gefapixant (MK‐7264), a P2X3 Receptor Antagonist, and the OATP1B1 Drug Transporter Substrate Pitavastatin

por McCrea, Jacqueline B., Hussain, Azher, Ma, Bennett, Garrett, Graigory C., Evers, Raymond, Laabs, John E., Stoch, S. Aubrey, Iwamoto, Marian
Publicado 2021

2563. Cytomegalovirus (CMV) Prophylaxis with Letermovir (LET) in Pediatric (Birth to < 18 years of age) Allogeneic Hematopoietic Cell Transplant (HCT) Recipients: Pharmacokinetics...

por Schulte, Johannes H, Gefen, Aharon, Groll, Andreas H, Fraser, Christopher J, Teal, Valerie L, Haber, Barbara A, Gilbert, Christopher L, McCrea, Jacqueline B, Patel, Mayankbhai, Menzel, Karsten, Badshah, Cyrus
Publicado 2023

A Single- and Multiple-Dose Study to Evaluate the Pharmacokinetics of Fixed-Dose Grazoprevir/Elbasvir in Healthy Chinese Participants

por Li, Haiyan, Yang, Zhenhua, Zhang, Shuang, Xu, Lin, Wei, Yudong, Jiang, Jun, Caro, Luzelena, Feng, Hwa-Ping, McCrea, Jacqueline B, Li, Meng, Xie, Shuang, Wang, Jiangdian, Zhao, Xu Min, Mu, Shengmei
Publicado 2020

On-the-road driving performance the morning after bedtime use of suvorexant 15 and 30 mg in healthy elderly

por Vermeeren, Annemiek, Vets, Eva, Vuurman, Eric F.P.M., Van Oers, Anita C.M., Jongen, Stefan, Laethem, Tine, Heirman, Ingeborg, Bautmans, An, Palcza, John, Li, Xiadong, Troyer, Matthew D., Wrishko, Rebecca, McCrea, Jacqueline, Sun, Hong
Publicado 2016

A single supratherapeutic dose of ridaforolimus does not prolong the QTc interval in patients with advanced cancer

por Lush, Richard M., Patnaik, Amita, Sullivan, Daniel, Papadopoulos, Kyriakos P., Trucksis, Michele, McCrea, Jacqueline, Cerchio, Kristine, Li, Xiaodong, Stroh, Mark, Selverian, Diana, Orford, Keith, Ebbinghaus, Scot, Agrawal, Nancy, Iwamoto, Marian, Wagner, John A., Tolcher, Anthony
Publicado 2012