Unfolded protein stress in the endoplasmic reticulum and mitochondria: a role in neurodegeneration

por Bernales, Sebastián, Soto, Marisol Morales, McCullagh, Emma
Publicado 2012

Coordinate control of gene expression noise and interchromosomal interactions in a MAPK pathway

por McCullagh, Emma, Seshan, Anupama, El-Samad, Hana, Madhani, Hiten D.
Publicado 2010

Natural history study of glycan accumulation in large animal models of GM2 gangliosidoses

por Cavender, Catlyn, Mangini, Linley, Van Vleet, Jeremy L., Corado, Carley, McCullagh, Emma, Gray-Edwards, Heather L., Martin, Douglas R., Crawford, Brett E., Lawrence, Roger
Publicado 2020

Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic

por Mendez, Aaron S, Alfaro, Jennifer, Morales-Soto, Marisol A, Dar, Arvin C, McCullagh, Emma, Gotthardt, Katja, Li, Han, Acosta-Alvear, Diego, Sidrauski, Carmela, Korennykh, Alexei V, Bernales, Sebastian, Shokat, Kevan M, Walter, Peter
Publicado 2015

Central nervous system pathology in preclinical MPS IIIB dogs reveals progressive changes in clinically relevant brain regions

por Egeland, Martin T., Tarczyluk-Wells, Marta M., Asmar, Melissa M., Adintori, Evan G., Lawrence, Roger, Snella, Elizabeth M., Jens, Jackie K., Crawford, Brett E., Wait, Jill C. M., McCullagh, Emma, Pinkstaff, Jason, Cooper, Jonathan D., Ellinwood, N. Matthew
Publicado 2020

Safety, pharmacokinetics and CNS distribution of tralesinidase alfa administered via intracerebroventricular infusion to juvenile cynomolgus monkeys

por Pinkstaff, Jason, McCullagh, Emma, Grover, Anita, Melton, Andrew C., Cherukuri, Anu, Wait, Jill CM, Nguyen, Annalisa, Butt, Mark T., Trombley, Jami L., Reed, Randall P., Adams, Eric.L., Boyd, Robert B., Chandra, Sundeep, Henshaw, Joshua, O’Neill, Charles A., Zanelli, Eric, Kovalchin, Joseph
Publicado 2023

Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide

por Cochrane, Dawn R, Bernales, Sebastián, Jacobsen, Britta M, Cittelly, Diana M, Howe, Erin N, D’Amato, Nicholas C, Spoelstra, Nicole S, Edgerton, Susan M, Jean, Annie, Guerrero, Javier, Gómez, Francisco, Medicherla, Satyanarayana, Alfaro, Iván E, McCullagh, Emma, Jedlicka, Paul, Torkko, Kathleen C, Thor, Ann D, Elias, Anthony D, Protter, Andrew A, Richer, Jennifer K
Publicado 2014

Tralesinidase Alfa Enzyme Replacement Therapy Prevents Disease Manifestations in a Canine Model of Mucopolysaccharidosis Type IIIB

por Ellinwood, N. Matthew, Valentine, Bethann N., Hess, Andrew S., Jens, Jackie K., Snella, Elizabeth M., Jamil, Maryam, Hostetter, Shannon J., Jeffery, Nicholas D., Smith, Jodi D., Millman, Suzanne T., Parsons, Rebecca L., Butt, Mark T., Chandra, Sundeep, Egeland, Martin T., Assis, Ana B., Nelvagal, Hemanth R., Cooper, Jonathan D., Nestrasil, Igor, Mueller, Bryon A., Labounek, Rene, Paulson, Amy, Prill, Heather, Liu, Xiao Ying, Zhou, Huiyu, Lawrence, Roger, Crawford, Brett E., Grover, Anita, Cherala, Ganesh, Melton, Andrew C., Cherukuri, Anu, Vuillemenot, Brian R., Wait, Jill C.M., O’Neill, Charles A., Pinkstaff, Jason, Kovalchin, Joseph, Zanelli, Eric, McCullagh, Emma
Publicado 2022