How can AI accelerate advances in physiology?

por McCulloch, Andrew D.
Publicado 2023

Mechano-Electric Coupling and Arrhythmogenic Current Generation in a Computational Model of Coupled Myocytes

por Timmermann, Viviane, McCulloch, Andrew D.
Publicado 2020

Toward a hierarchy of mechanisms in CaMKII-mediated arrhythmia

por Vincent, Kevin P., McCulloch, Andrew D., Edwards, Andrew G.
Publicado 2014

Flexibility in energy metabolism supports hypoxia tolerance in Drosophila flight muscle: metabolomic and computational systems analysis

por Feala, Jacob D, Coquin, Laurence, McCulloch, Andrew D, Paternostro, Giovanni
Publicado 2007

Metabolomic and flux-balance analysis of age-related decline of hypoxia tolerance in Drosophila muscle tissue

por Coquin, Laurence, Feala, Jacob D, McCulloch, Andrew D, Paternostro, Giovanni
Publicado 2008

Nuclear mechanosignaling in striated muscle diseases

por Zhang, Bo, Powers, Joseph D., McCulloch, Andrew D., Chi, Neil C.
Publicado 2023

Calcium and IP3 dynamics in cardiac myocytes: experimental and computational perspectives and approaches

por Hohendanner, Felix, McCulloch, Andrew D., Blatter, Lothar A., Michailova, Anushka P.
Publicado 2014

Insights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants—Genotype to Cellular Phenotype

por Dewan, Sukriti, McCabe, Kimberly J., Regnier, Michael, McCulloch, Andrew D.
Publicado 2017

The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart

por Herum, Kate M., Lunde, Ida G., McCulloch, Andrew D., Christensen, Geir
Publicado 2017

Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction

por Gilles, George, McCulloch, Andrew D., Brakebusch, Cord H., Herum, Kate M.
Publicado 2020

Mechanisms of transmurally varying myocyte electromechanics in an integrated computational model

por Campbell, Stuart G., Flaim, Sarah N., Leem, Chae H., McCulloch, Andrew D.
Publicado 2008

Tissue-Specific Optical Mapping Models of Swine Atria Informed by Optical Coherence Tomography

por Lye, Theresa H., Vincent, Kevin P., McCulloch, Andrew D., Hendon, Christine P.
Publicado 2018

Arrhythmogenic Current Generation by Myofilament-Triggered Ca(2+) Release and Sarcomere Heterogeneity

por Timmermann, Viviane, Edwards, Andrew G., Wall, Samuel T., Sundnes, Joakim, McCulloch, Andrew D.
Publicado 2019

Mechanical regulation of cardiac fibroblast profibrotic phenotypes

por Herum, Kate M., Choppe, Jonas, Kumar, Aditya, Engler, Adam J., McCulloch, Andrew D.
Publicado 2017

Predictive model identifies key network regulators of cardiomyocyte mechano-signaling

por Tan, Philip M., Buchholz, Kyle S., Omens, Jeffrey H., McCulloch, Andrew D., Saucerman, Jeffrey J.
Publicado 2017

Metabolism as means for hypoxia adaptation: metabolic profiling and flux balance analysis

por Feala, Jacob D, Coquin, Laurence, Zhou, Dan, Haddad, Gabriel G, Paternostro, Giovanni, McCulloch, Andrew D
Publicado 2009

Statistical Properties and Robustness of Biological Controller-Target Networks

por Feala, Jacob D., Cortes, Jorge, Duxbury, Phillip M., McCulloch, Andrew D., Piermarocchi, Carlo, Paternostro, Giovanni
Publicado 2012

Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling

por Zhang, Jason Z., Nguyen, Andy H., Miyamoto, Shigeki, Heller Brown, Joan, McCulloch, Andrew D., Zhang, Jin
Publicado 2020

Regional variations in ex-vivo diffusion tensor anisotropy are associated with cardiomyocyte remodeling in rats after left ventricular pressure overload

por Carruth, Eric D., Teh, Irvin, Schneider, Jurgen E., McCulloch, Andrew D., Omens, Jeffrey H., Frank, Lawrence R.
Publicado 2020

Bridging scales through multiscale modeling: a case study on protein kinase A

por Boras, Britton W., Hirakis, Sophia P., Votapka, Lane W., Malmstrom, Robert D., Amaro, Rommie E., McCulloch, Andrew D.
Publicado 2015