Reprogrammable CRISPR/Cas9-based system for inducing site-specific DNA methylation

por McDonald, James I., Celik, Hamza, Rois, Lisa E., Fishberger, Gregory, Fowler, Tolison, Rees, Ryan, Kramer, Ashley, Martens, Andrew, Edwards, John R., Challen, Grant A.
Publicado 2016

Epigenetic activation of the prostaglandin receptor EP4 promotes resistance to endocrine therapy for breast cancer

por Hiken, Jeffrey F., McDonald, James I., Decker, Keith F., Sanchez, Cesar, Hoog, Jeremy, VanderKraats, Nathan D., Jung, Kyle L., Akinhanmi, Margaret, Rois, Lisa E., Ellis, Matthew J., Edwards, John R.
Publicado 2016

Inhibiting DNA methylation and RNA editing upregulates immunogenic RNA to transform the tumor microenvironment and prolong survival in ovarian cancer

por Gomez, Stephanie, Cox, Olivia L, Walker, Reddick R, Rentia, Uzma, Hadley, Melissa, Arthofer, Elisa, Diab, Noor, Grundy, Erin E, Kanholm, Tomas, McDonald, James I, Kobyra, Julie, Palmer, Erica, Noonepalle, Satish, Villagra, Alejandro, Leitenberg, David, Bollard, Catherine M, Saunthararajah, Yogen, Chiappinelli, Katherine B
Publicado 2022