Targeting mutant estrogen receptors

por Wardell, Suzanne E, Norris, John D, McDonnell, Donald P
Publicado 2019

Aryl hydrocarbon receptor knock-out exacerbates choroidal neovascularization via multiple pathogenic pathways

por Choudhary, Mayur, Kazmin, Dmitri, Hu, Peng, Thomas, Russell S, McDonnell, Donald P, Malek, Goldis
Publicado 2015

Decoding the Inversion Symmetry Underlying Transcription Factor DNA-Binding Specificity and Functionality in the Genome

por Coons, Laurel A., Burkholder, Adam B., Hewitt, Sylvia C., McDonnell, Donald P., Korach, Kenneth S.
Publicado 2019

Dysregulated cholesterol homeostasis results in resistance to ferroptosis increasing tumorigenicity and metastasis in cancer

por Liu, Wen, Chakraborty, Binita, Safi, Rachid, Kazmin, Dmitri, Chang, Ching-yi, McDonnell, Donald P.
Publicado 2021

Single-step purification of full-length human androgen receptor

por Juzumiene, Dalia, Chang, Ching-yi, Fan, Daju, Hartney, Tanya, Norris, John D., McDonnell, Donald P.
Publicado 2005

Development and Characterization of a Luciferase Labeled, Syngeneic Murine Model of Ovarian Cancer

por Russell, Shonagh, Lim, Felicia, Peters, Pamela N., Wardell, Suzanne E., Whitaker, Regina, Chang, Ching-Yi, Previs, Rebecca A., McDonnell, Donald P.
Publicado 2022

MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer

por Xu, Xin, Zhang, Yun, Jasper, Jeff, Lykken, Erik, Alexander, Peter B., Markowitz, Geoffrey J., McDonnell, Donald P., Li, Qi-Jing, Wang, Xiao-Fan
Publicado 2016

Cystine addiction of triple negative breast cancer associated with EMT augmented death signaling

por Tang, Xiaohu, Ding, Chien-Kuang, Wu, Jianli, Sjol, Jessie, Wardell, Suzanne, George, Daniel, McDonnell, Donald P., Hsu, David S., Chang, Jeffrey T, Chi, Jen-Tsan
Publicado 2016

Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors

por Anderson, Gray R., Wardell, Suzanne E., Cakir, Merve, Yip, Catherine, Ahn, Yeong-ran, Ali, Moiez, Yllanes, Alexander P., Chao, Christina A., McDonnell, Donald P., Wood, Kris C.
Publicado 2018

Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance

por Salami, Jemilat, Alabi, Shanique, Willard, Ryan R., Vitale, Nick J., Wang, Jing, Dong, Hanqing, Jin, Meizhong, McDonnell, Donald P., Crew, Andrew P., Neklesa, Taavi K., Crews, Craig M.
Publicado 2018

Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activity in antitumo...

por Wardell, Suzanne E., Yllanes, Alexander P., Chao, Christina A., Bae, Yeeun, Andreano, Kaitlyn J., Desautels, Taylor K., Heetderks, Kendall A., Blitzer, Jeremy T., Norris, John D., McDonnell, Donald P.
Publicado 2019

Correction to: Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activ...

por Wardell, Suzanne E., Yllanes, Alexander P., Chao, Christina A., Bae, Yeeun, Andreano, Kaitlyn J., Desautels, Taylor K., Heetderks, Kendall A., Blitzer, Jeremy T., Norris, John D., McDonnell, Donald P.
Publicado 2019

ABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1

por Mayro, Benjamin, Hoj, Jacob P., Cerda-Smith, Christian G., Hutchinson, Haley M., Caminear, Michael W., Thrash, Hannah L., Winter, Peter S., Wardell, Suzanne E., McDonnell, Donald P., Wu, Colleen, Wood, Kris C., Pendergast, Ann Marie
Publicado 2023

Neuronal CaMKK2 promotes immunosuppression and checkpoint blockade resistance in glioblastoma

por Tomaszewski, William H., Waibl-Polania, Jessica, Chakraborty, Molly, Perera, Jonathan, Ratiu, Jeremy, Miggelbrink, Alexandra, McDonnell, Donald P., Khasraw, Mustafa, Ashley, David M., Fecci, Peter E., Racioppi, Luigi, Sanchez-Perez, Luis, Gunn, Michael D., Sampson, John H.
Publicado 2022

Chemotherapy enriches for an invasive triple-negative breast tumor cell subpopulation expressing a precursor form of N-cadherin on the cell surface

por Nelson, Erik R., Li, Shenduo, Kennedy, Margaret, Payne, Sturgis, Kilibarda, Kelly, Groth, Jeffrey, Bowie, Michelle, Parilla-Castellar, Edgardo, de Ridder, Gustaaf, Marcom, Paul Kelly, Lyes, Matthew, Peterson, Bercedis L., Cook, Michael, Pizzo, Salvatore V., McDonnell, Donald P., Bachelder, Robin E.
Publicado 2016

Targeting CaMKK2 Inhibits Actin Cytoskeletal Assembly to Suppress Cancer Metastasis

por Mukherjee, Debarati, Previs, Rebecca A., Haines, Corinne, Al Abo, Muthana, Juras, Patrick K., Strickland, Kyle C., Chakraborty, Binita, Artham, Sandeep, Whitaker, Regina S., Hebert, Katherine, Fontenot, Jake, Patierno, Steven R., Freedman, Jennifer A., Lau, Frank H., Burow, Matthew E., Chang, Ching-Yi, McDonnell, Donald P.
Publicado 2023

Inhibiting androgen receptor nuclear entry in castration-resistant prostate cancer

por Pollock, Julie A., Wardell, Suzanne E., Parent, Alexander A., Stagg, David B., Ellison, Stephanie J., Alley, Holly M., Chao, Christina A., Lawrence, Scott A., Stice, James P., Spasojevic, Ivan, Baker, Jennifer G., Kim, Sung Hoon, McDonnell, Donald P., Katzenellenbogen, John A., Norris, John D.
Publicado 2016

The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells

por Baek, Amy E., Yu, Yen-Rei A., He, Sisi, Wardell, Suzanne E., Chang, Ching-Yi, Kwon, Sanghoon, Pillai, Ruchita V., McDowell, Hannah B., Thompson, J. Will, Dubois, Laura G., Sullivan, Patrick M., Kemper, Jongsook K., Gunn, Michael D., McDonnell, Donald P., Nelson, Erik R.
Publicado 2017

Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice

por Yu, Liming, Xu, Lin, Chu, Haiyan, Peng, Jun, Sacharidou, Anastasia, Hsieh, Hsi-hsien, Weinstock, Ada, Khan, Sohaib, Ma, Liqian, Durán, José Gabriel Barcia, McDonald, Jeffrey, Nelson, Erik R., Park, Sunghee, McDonnell, Donald P., Moore, Kathryn J., Huang, Lily Jun-shen, Fisher, Edward A., Mineo, Chieko, Huang, Linzhang, Shaul, Philip W.
Publicado 2023

CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer

por Racioppi, Luigi, Nelson, Erik R., Huang, Wei, Mukherjee, Debarati, Lawrence, Scott A., Lento, William, Masci, Anna Maria, Jiao, Yiquin, Park, Sunghee, York, Brian, Liu, Yaping, Baek, Amy E., Drewry, David H., Zuercher, William J., Bertani, Francesca R., Businaro, Luca, Geradts, Joseph, Hall, Allison, Means, Anthony R., Chao, Nelson, Chang, Ching-yi, McDonnell, Donald P.
Publicado 2019