Mitochondrial stress causes neuronal dysfunction via an ATF4-dependent increase in L-2-hydroxyglutarate

por Hunt, Rachel J., Granat, Lucy, McElroy, Gregory S., Ranganathan, Ramya, Chandel, Navdeep S., Bateman, Joseph M.
Publicado 2019

Metabolic determinants of cellular fitness dependent on mitochondrial reactive oxygen species

por Kong, Hyewon, Reczek, Colleen R., McElroy, Gregory S., Steinert, Elizabeth M., Wang, Tim, Sabatini, David M., Chandel, Navdeep S.
Publicado 2020

A Systems Approach Dissociates Fructose-Induced Liver Triglyceride from Hypertriglyceridemia and Hyperinsulinemia in Male Mice

por Doridot, Ludivine, Hannou, Sarah A., Krawczyk, Sarah A., Tong, Wenxin, Kim, Mi-Sung, McElroy, Gregory S., Fowler, Alan J., Astapova, Inna I., Herman, Mark A.
Publicado 2021

Mitochondrial ubiquinol oxidation is necessary for tumor growth

por Martínez-Reyes, Inmaculada, Robles Cardona, Luzivette, Kong, Hyewon, Vasan, Karthik, McElroy, Gregory S., Werner, Marie, Kihshen, Hermon, Reczek, Colleen R., Weinberg, Samuel E., Gao, Peng, Steinert, Elizabeth M., Piseaux, Raul, Budinger, G.R. Scott, Chandel, Navdeep S.
Publicado 2020

Human iPSC-derived cerebral organoids model features of Leigh syndrome and reveal abnormal corticogenesis

por Romero-Morales, Alejandra I., Robertson, Gabriella L., Rastogi, Anuj, Rasmussen, Megan L., Temuri, Hoor, McElroy, Gregory Scott, Chakrabarty, Ram Prosad, Hsu, Lawrence, Almonacid, Paula M., Millis, Bryan A., Chandel, Navdeep S., Cartailler, Jean-Philippe, Gama, Vivian
Publicado 2022

Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein

por Shum, Andrew, Zaichick, Sofia, McElroy, Gregory S., D’Alessandro, Karis, Alasady, Milad J., Novakovic, Michaela, Peng, Wesley, Grebenik, Ekaterina A., Chung, Daayun, Flanagan, Margaret E., Smith, Roger, Morales, Alejandro, Stumpf, Laetitia, McGrath, Kaitlyn, Krainc, Dimitri, Mendillo, Marc L., Prakriya, Murali, Chandel, Navdeep S., Caraveo, Gabriela
Publicado 2023

Lactate-dependent transcriptional regulation controls mammalian eye morphogenesis

por Takata, Nozomu, Miska, Jason M., Morgan, Marc A., Patel, Priyam, Billingham, Leah K., Joshi, Neha, Schipma, Matthew J., Dumar, Zachary J., Joshi, Nikita R., Misharin, Alexander V., Embry, Ryan B., Fiore, Luciano, Gao, Peng, Diebold, Lauren P., McElroy, Gregory S., Shilatifard, Ali, Chandel, Navdeep S., Oliver, Guillermo
Publicado 2023

Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice

por McElroy, Gregory S., Chakrabarty, Ram P., D’Alessandro, Karis B., Hu, Yuan-Shih, Vasan, Karthik, Tan, Jerica, Stoolman, Joshua S., Weinberg, Samuel E., Steinert, Elizabeth M., Reyfman, Paul A., Singer, Benjamin D., Ladiges, Warren C., Gao, Lin, Lopéz-Barneo, José, Ridge, Karen, Budinger, G. R. Scott, Chandel, Navdeep S.
Publicado 2022

Author Correction: Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice

por McElroy, Gregory S., Chakrabarty, Ram P., D’Alessandro, Karis B., Hu, Yuan-Shih, Vasan, Karthik, Tan, Jerica, Stoolman, Joshua S., Weinberg, Samuel E., Steinert, Elizabeth M., Reyfman, Paul A., Singer, Benjamin D., Ladiges, Warren C., Gao, Lin, Lopéz‑Barneo, José, Ridge, Karen, Budinger, G. R. Scott, Chandel, Navdeep S.
Publicado 2022