A sensitivity analysis of RNA folding nearest neighbor parameters identifies a subset of free energy parameters with the greatest impact on RNA secondary structure prediction

por Zuber, Jeffrey, Sun, Hongying, Zhang, Xiaoju, McFadyen, Iain, Mathews, David H.
Publicado 2017

Analysis of RNA nearest neighbor parameters reveals interdependencies and quantifies the uncertainty in RNA secondary structure prediction

por Zuber, Jeffrey, Cabral, B. Joseph, McFadyen, Iain, Mauger, David M., Mathews, David H.
Publicado 2018

Therapeutic enzyme engineering using a generative neural network

por Giessel, Andrew, Dousis, Athanasios, Ravichandran, Kanchana, Smith, Kevin, Sur, Sreyoshi, McFadyen, Iain, Zheng, Wei, Licht, Stuart
Publicado 2022

Effectiveness of an Online Course on Fracture-Related Infections

por Azi, Matheus Lemos, Kojima, Kodi Edson, Pesántez, Rodrigo, Carabelli, Guido, Borens, Olivier, McFadyen, Iain, Valderrama-Molina, Carlos Oliver
Publicado 2022

mRNA structure regulates protein expression through changes in functional half-life

por Mauger, David M., Cabral, B. Joseph, Presnyak, Vladimir, Su, Stephen V., Reid, David W., Goodman, Brooke, Link, Kristian, Khatwani, Nikhil, Reynders, John, Moore, Melissa J., McFadyen, Iain J.
Publicado 2019

Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines

por Hassett, Kimberly J., Benenato, Kerry E., Jacquinet, Eric, Lee, Aisha, Woods, Angela, Yuzhakov, Olga, Himansu, Sunny, Deterling, Jessica, Geilich, Benjamin M., Ketova, Tatiana, Mihai, Cosmin, Lynn, Andy, McFadyen, Iain, Moore, Melissa J., Senn, Joseph J., Stanton, Matthew G., Almarsson, Örn, Ciaramella, Giuseppe, Brito, Luis A.
Publicado 2019