Editorial: Structural understanding of the functional consequences of missense mutation

por Tian, Jian, McFarland, Christopher D., Woodard, Jaie
Publicado 2023

Most cancers carry a substantial deleterious load due to Hill-Robertson interference

por Tilk, Susanne, Tkachenko, Svyatoslav, Curtis, Christina, Petrov, Dmitri A, McFarland, Christopher D
Publicado 2022

Frequency-dependent ecological interactions increase the prevalence, and shape the distribution, of pre-existing drug resistance

por Maltas, Jeff, Tadele, Dagim Shiferaw, Durmaz, Arda, McFarland, Christopher D., Hinczewski, Michael, Scott, Jacob G.
Publicado 2023

A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo

por Rogers, Zoë N., McFarland, Christopher D., Winters, Ian P., Naranjo, Santiago, Chuang, Chen-Hua, Petrov, Dmitri, Winslow, Monte M.
Publicado 2017

Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity

por Winters, Ian P., Chiou, Shin-Heng, Paulk, Nicole K., McFarland, Christopher D., Lalgudi, Pranav V., Ma, Rosanna K., Lisowski, Leszek, Connolly, Andrew J., Petrov, Dmitri A., Kay, Mark A., Winslow, Monte M.
Publicado 2017