Matrix reboot: IL-17 signals CAFs to create a second tumor T cell checkpoint

por McGeachy, Mandy J.
Publicado 2022

CD73 is expressed by inflammatory Th17 cells in experimental autoimmune encephalomyelitis but does not limit differentiation or pathogenesis

por Hernandez-Mir, Gerard, McGeachy, Mandy J.
Publicado 2017

The metabolism-modulating activity of IL-17 signaling in health and disease

por Bechara, Rami, McGeachy, Mandy J., Gaffen, Sarah L.
Publicado 2021

Temporary consumption of western diet trains the immune system to reduce future gut inflammation

por Wu, Dongwen, Wang, Xiaotong, Yang, Xiang, Gu, Lei, McGeachy, Mandy J., Liu, Xiaowei
Publicado 2023

Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells

por Ahern, Philip P., Schiering, Chris, Buonocore, Sofia, McGeachy, Mandy J., Cua, Dan J., Maloy, Kevin J., Powrie, Fiona
Publicado 2010

Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells

por Ahern, Philip P., Schiering, Chris, Buonocore, Sofia, McGeachy, Mandy J., Cua, Dan J., Maloy, Kevin J., Powrie, Fiona
Publicado 2011

Analysis of CXCR5(+)Th17 cells in relation to disease activity and TNF inhibitor therapy in Rheumatoid Arthritis

por Singh, Deepika, Henkel, Matthew, Sendon, Bernadette, Feng, June, Fabio, Anthony, Metes, Diana, Moreland, Larry W., McGeachy, Mandy J.
Publicado 2016

The RNA-binding protein IMP2 drives a stromal-Th17 cell circuit in autoimmune neuroinflammation

por Bechara, Rami, Amatya, Nilesh, Majumder, Saikat, Zhou, Chunsheng, Li, Yang, Liu, Qixing, McGeachy, Mandy J., Gaffen, Sarah L.
Publicado 2022

Rheumatoid arthritis patients exhibit impaired Candida albicans-specific Th17 responses

por Bishu, Shrinivas, Su, Ee Wern, Wilkerson, Erich R, Reckley, Kelly A, Jones, Donald M, McGeachy, Mandy J, Gaffen, Sarah L, Levesque, Marc C
Publicado 2014

Inflammatory Th17 Cells Express Integrin α(v)β(3) for Pathogenic Function

por Du, Fang, Garg, Abhishek V., Kosar, Karis, Majumder, Saikat, Kugler, David G., Mir, Gerard Hernandez, Maggio, Maria, Henkel, Matthew, Lacy-Hulbert, Adam, McGeachy, Mandy J.
Publicado 2016

Noncanonical STAT3 activity sustains pathogenic Th17 proliferation and cytokine response to antigen

por Poholek, Catherine H., Raphael, Itay, Wu, Dongwen, Revu, Shankar, Rittenhouse, Natalie, Uche, Uzodinma U., Majumder, Saikat, Kane, Lawrence P., Poholek, Amanda C., McGeachy, Mandy J.
Publicado 2020

Endogenous Interleukin-17a Contributes to Normal Spatial Memory Retention but Does Not Affect Early Behavioral or Neuropathological Outcomes after Experimental Traumatic Brain Inju...

por Simon, Dennis W., Raphael, Itay, Johnson, Kendall M., Dixon, C. Edward, Vagni, Vincent, Janesko-Feldman, Keri, Kochanek, Patrick M., Bayir, Hülya, Clark, Robert S.B., McGeachy, Mandy J.
Publicado 2022

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling

por Boniface, Katia, Bak-Jensen, Kristian S., Li, Ying, Blumenschein, Wendy M., McGeachy, Mandy J., McClanahan, Terrill K., McKenzie, Brent S., Kastelein, Robert A., Cua, Daniel J., de Waal Malefyt, René
Publicado 2009

Delinking CARD9 and IL-17: CARD9 Protects against Candida tropicalis Infection through a TNF-α–Dependent, IL-17–Independent Mechanism

por Whibley, Natasha, Jaycox, Jillian R., Reid, Delyth, Garg, Abhishek V., Taylor, Julie A., Clancy, Cornelius J., Nguyen, M. Hong, Biswas, Partha S., McGeachy, Mandy J., Brown, Gordon D., Gaffen, Sarah L.
Publicado 2015

Generation of Pathogenic Th17 Cells in the Absence of TGF-β Signaling

por Ghoreschi, Kamran, Laurence, Arian, Yang, Xiang-Ping, Tato, Cristina M., McGeachy, Mandy J., Konkel, Joanne, Ramos, Haydeé L., Wei, Lai, Davidson, Todd, Bouladoux, Nicolas, Grainger, John, Chen, Qian, Kanno, Yuka, Watford, Wendy T., Sun, Hong-Wei, Eberl, Gérard, Shevach, Ethan, Belkaid, Yasmine, Cua, Daniel J., Chen, Wanjun, O’Shea, John J.
Publicado 2010

Oral-resident natural Th17 cells and γδ T cells control opportunistic Candida albicans infections

por Conti, Heather R., Peterson, Alanna C., Brane, Lucas, Huppler, Anna R., Hernández-Santos, Nydiaris, Whibley, Natasha, Garg, Abhishek V., Simpson-Abelson, Michelle R., Gibson, Gregory A., Mamo, Anna J., Osborne, Lisa C., Bishu, Shrinivas, Ghilardi, Nico, Siebenlist, Ulrich, Watkins, Simon C., Artis, David, McGeachy, Mandy J., Gaffen, Sarah L.
Publicado 2014

Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue

por Donlin, Laura T., Rao, Deepak A., Wei, Kevin, Slowikowski, Kamil, McGeachy, Mandy J., Turner, Jason D., Meednu, Nida, Mizoguchi, Fumitaka, Gutierrez-Arcelus, Maria, Lieb, David J., Keegan, Joshua, Muskat, Kaylin, Hillman, Joshua, Rozo, Cristina, Ricker, Edd, Eisenhaure, Thomas M., Li, Shuqiang, Browne, Edward P., Chicoine, Adam, Sutherby, Danielle, Noma, Akiko, Nusbaum, Chad, Kelly, Stephen, Pernis, Alessandra B., Ivashkiv, Lionel B., Goodman, Susan M., Robinson, William H., Utz, Paul J., Lederer, James A., Gravallese, Ellen M., Boyce, Brendan F., Hacohen, Nir, Pitzalis, Costantino, Gregersen, Peter K., Firestein, Gary S., Raychaudhuri, Soumya, Moreland, Larry W., Holers, V. Michael, Bykerk, Vivian P., Filer, Andrew, Boyle, David L., Brenner, Michael B., Anolik, Jennifer H.
Publicado 2018

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

por Zhang, Fan, Wei, Kevin, Slowikowski, Kamil, Fonseka, Chamith Y., Rao, Deepak A., Kelly, Stephen, Goodman, Susan M., Tabechian, Darren, Hughes, Laura B., Salomon-Escoto, Karen, Watts, Gerald F. M., Jonsson, Anna H., Rangel-Moreno, Javier, Pellett, Nida M., Rozo, Cristina, Apruzzese, William, Eisenhaure, Thomas M., Lieb, David J., Boyle, David L., Mandelin, Arthur M., Boyce, Brendan F., DiCarlo, Edward, Gravallese, Ellen M., Gregersen, Peter K., Moreland, Larry, Firestein, Gary S., Hacohen, Nir, Nusbaum, Chad, Lederer, James A., Perlman, Harris, Pitzalis, Costantino, Filer, Andrew, Holers, V. Michael, Bykerk, Vivian P., Donlin, Laura T., Anolik, Jennifer H., Brenner, Michael B., Raychaudhuri, Soumya, Albrecht, Jennifer, Bridges, S. Louis, Buckley, Christopher D., Buckner, Jane H., Dolan, James, Guthridge, Joel M., Gutierrez-Arcelus, Maria, Ivashkiv, Lionel B., James, Eddie A., James, Judith A., Keegan, Josh, Lee, Yvonne C., McGeachy, Mandy J., McNamara, Michael A., Mears, Joseph R., Mizoguchi, Fumitaka, Nguyen, Jennifer P., Noma, Akiko, Orange, Dana E., Rohani-Pichavant, Mina, Ritchlin, Christopher, Robinson, William H., Seshadri, Anupamaa, Sutherby, Danielle, Seifert, Jennifer, Turner, Jason D., Utz, Paul J.
Publicado 2019