Monitoring the dynamics of Src activity in response to anti-invasive dasatinib treatment at a subcellular level using dual intravital imaging

por Nobis, Max, McGhee, Ewan J, Herrmann, David, Magenau, Astrid, Morton, Jennifer P, Anderson, Kurt I, Timpson, Paul
Publicado 2014

Live Cell in Vitro and in Vivo Imaging Applications: Accelerating Drug Discovery

por Isherwood, Beverley, Timpson, Paul, McGhee, Ewan J, Anderson, Kurt I, Canel, Marta, Serrels, Alan, Brunton, Valerie G, Carragher, Neil O
Publicado 2011

Accepting from the best donor; analysis of long-lifetime donor fluorescent protein pairings to optimise dynamic FLIM-based FRET experiments

por Martin, Kirsty J., McGhee, Ewan J., Schwarz, Juliana P., Drysdale, Martin, Brachmann, Saskia M., Stucke, Volker, Sansom, Owen J., Anderson, Kurt I.
Publicado 2018

Polarized Cell Motility Induces Hydrogen Peroxide to Inhibit Cofilin via Cysteine Oxidation

por Cameron, Jenifer M., Gabrielsen, Mads, Chim, Ya Hua, Munro, June, McGhee, Ewan J., Sumpton, David, Eaton, Philip, Anderson, Kurt I., Yin, Huabing, Olson, Michael F.
Publicado 2015

ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth

por Rath, Nicola, Morton, Jennifer P, Julian, Linda, Helbig, Lena, Kadir, Shereen, McGhee, Ewan J, Anderson, Kurt I, Kalna, Gabriela, Mullin, Margaret, Pinho, Andreia V, Rooman, Ilse, Samuel, Michael S, Olson, Michael F
Publicado 2016

ROS Production and NF-κB Activation Triggered by RAC1 Facilitate WNT-Driven Intestinal Stem Cell Proliferation and Colorectal Cancer Initiation

por Myant, Kevin B., Cammareri, Patrizia, McGhee, Ewan J., Ridgway, Rachel A., Huels, David J., Cordero, Julia B., Schwitalla, Sarah, Kalna, Gabriela, Ogg, Erinn-Lee, Athineos, Dimitris, Timpson, Paul, Vidal, Marcos, Murray, Graeme I., Greten, Florian R., Anderson, Kurt I., Sansom, Owen J.
Publicado 2013

Analysis of Prostate Cancer Tumor Microenvironment Identifies Reduced Stromal CD4 Effector T-cell Infiltration in Tumors with Pelvic Nodal Metastasis

por Ntala, Chara, Salji, Mark, Salmond, Jonathan, Officer, Leah, Teodosio, Ana Vieira, Blomme, Arnaud, McGhee, Ewan J., Powley, Ian, Ahmad, Imran, Kruithof-de Julio, Marianna, Thalmann, George, Roberts, Ed, Goodyear, Carl S., Jamaspishvili, Tamara, Berman, David M., Carlin, Leo M., Le Quesne, John, Leung, Hing Y.
Publicado 2021

The Rac-FRET Mouse Reveals Tight Spatiotemporal Control of Rac Activity in Primary Cells and Tissues

por Johnsson, Anna-Karin E., Dai, Yanfeng, Nobis, Max, Baker, Martin J., McGhee, Ewan J., Walker, Simon, Schwarz, Juliane P., Kadir, Shereen, Morton, Jennifer P., Myant, Kevin B., Huels, David J., Segonds-Pichon, Anne, Sansom, Owen J., Anderson, Kurt I., Timpson, Paul, Welch, Heidi C.E.
Publicado 2014

CSF1R(+) Macrophages Sustain Pancreatic Tumor Growth through T Cell Suppression and Maintenance of Key Gene Programs that Define the Squamous Subtype

por Candido, Juliana B., Morton, Jennifer P., Bailey, Peter, Campbell, Andrew D., Karim, Saadia A., Jamieson, Thomas, Lapienyte, Laura, Gopinathan, Aarthi, Clark, William, McGhee, Ewan J., Wang, Jun, Escorcio-Correia, Monica, Zollinger, Raphael, Roshani, Rozita, Drew, Lisa, Rishi, Loveena, Arkell, Rebecca, Evans, T.R. Jeffry, Nixon, Colin, Jodrell, Duncan I., Wilkinson, Robert W., Biankin, Andrew V., Barry, Simon T., Balkwill, Frances R., Sansom, Owen J.
Publicado 2018

Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium

por Reid, Steven E, Kay, Emily J, Neilson, Lisa J, Henze, Anne‐Theres, Serneels, Jens, McGhee, Ewan J, Dhayade, Sandeep, Nixon, Colin, Mackey, John BG, Santi, Alice, Swaminathan, Karthic, Athineos, Dimitris, Papalazarou, Vasileios, Patella, Francesca, Román‐Fernández, Álvaro, ElMaghloob, Yasmin, Hernandez‐Fernaud, Juan Ramon, Adams, Ralf H, Ismail, Shehab, Bryant, David M, Salmeron‐Sanchez, Manuel, Machesky, Laura M, Carlin, Leo M, Blyth, Karen, Mazzone, Massimiliano, Zanivan, Sara
Publicado 2017

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue

por Erami, Zahra, Herrmann, David, Warren, Sean C., Nobis, Max, McGhee, Ewan J., Lucas, Morghan C., Leung, Wilfred, Reischmann, Nadine, Mrowinska, Agata, Schwarz, Juliane P., Kadir, Shereen, Conway, James R.W., Vennin, Claire, Karim, Saadia A., Campbell, Andrew D., Gallego-Ortega, David, Magenau, Astrid, Murphy, Kendelle J., Ridgway, Rachel A., Law, Andrew M., Walters, Stacey N., Grey, Shane T., Croucher, David R., Zhang, Lei, Herzog, Herbert, Hardeman, Edna C., Gunning, Peter W., Ormandy, Christopher J., Evans, T.R. Jeffry, Strathdee, Douglas, Sansom, Owen J., Morton, Jennifer P., Anderson, Kurt I., Timpson, Paul
Publicado 2015