The design of a Bayesian adaptive clinical trial of tranexamic acid in severely injured children

por VanBuren, John M., Casper, T. Charles, Nishijima, Daniel K., Kuppermann, Nathan, Lewis, Roger J., Dean, J. Michael, McGlothlin, Anna
Publicado 2021

Practical Considerations and Recommendations for Master Protocol Framework: Basket, Umbrella and Platform Trials

por Lu, Chengxing (Cindy), Li, Xiaoyun (Nicole), Broglio, Kristine, Bycott, Paul, Jiang, Qi, Li, Xiaoming, McGlothlin, Anna, Tian, Hong, Ye, Jingjing
Publicado 2021

The Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) Protocol: a prospective, multi-center, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial

por Hager, David N., Hooper, Michael H., Bernard, Gordon R., Busse, Laurence W., Ely, E. Wesley, Fowler, Alpha A., Gaieski, David F., Hall, Alex, Hinson, Jeremiah S., Jackson, James C., Kelen, Gabor D., Levine, Mark, Lindsell, Christopher J., Malone, Richard E., McGlothlin, Anna, Rothman, Richard E., Viele, Kert, Wright, David W., Sevransky, Jonathan E., Martin, Greg S.
Publicado 2019

Update to the Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) protocol: statistical analysis plan for a prospective, multicenter, double-blind, adaptive sample size, randomized...

por Lindsell, Christopher J., McGlothlin, Anna, Nwosu, Samuel, Rice, Todd W., Hall, Alex, Bernard, Gordon R., Busse, Laurence W., Ely, E. Wesley, Fowler, Alpha A., Gaieski, David F., Hinson, Jeremiah S., Hooper, Michael H., Jackson, James C., Kelen, Gabor D., Levine, Mark, Martin, Greg S., Rothman, Richard E., Sevransky, Jonathan E., Viele, Kert, Wright, David W., Hager, David N.
Publicado 2019

In response: Letter on update to the Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) protocol

por Lindsell, Christopher J., McGlothlin, Anna, Nwosu, Samuel, Rice, Todd W., Hall, Alex, Bernard, Gordon R., Busse, Laurence W., Ely, E. Wesley, Fowler, Alpha A., Gaieski, David F., Hinson, Jeremiah S., Hooper, Michael H., Jackson, James C., Kelen, Gabor D., Levine, Mark, Martin, Greg S., Rothman, Richard E., Sevransky, Jonathan E., Viele, Kert, Wright, David W., Hager, David N.
Publicado 2020

Hypothermia for Patients Requiring Evacuation of Subdural Hematoma: A Multicenter Randomized Clinical Trial

por Hergenroeder, Georgene W., Yokobori, Shoji, Choi, Huimahn Alex, Schmitt, Karl, Detry, Michelle A., Schmitt, Lisa H., McGlothlin, Anna, Puccio, Ava M., Jagid, Jonathan, Kuroda, Yasuhiro, Nakamura, Yukihiko, Suehiro, Eiichi, Ahmad, Faiz, Viele, Kert, Wilde, Elisabeth A., McCauley, Stephen R., Kitagawa, Ryan S., Temkin, Nancy R., Timmons, Shelly D., Diringer, Michael N., Dash, Pramod K., Bullock, Ross, Okonkwo, David O., Berry, Donald A., Kim, Dong H.
Publicado 2021

Association of Subcutaneous or Intravenous Administration of Casirivimab and Imdevimab Monoclonal Antibodies With Clinical Outcomes in Adults With COVID-19

por McCreary, Erin K., Bariola, J. Ryan, Wadas, Richard J., Shovel, Judith A., Wisniewski, Mary Kay, Adam, Michelle, Albin, Debbie, Minnier, Tami, Schmidhofer, Mark, Meyers, Russell, Marroquin, Oscar C., Collins, Kevin, Garrard, William, Berry, Lindsay R., Berry, Scott, Crawford, Amy M., McGlothlin, Anna, Linstrum, Kelsey, Nakayama, Anna, Montgomery, Stephanie K., Snyder, Graham M., Yealy, Donald M., Angus, Derek C., Kip, Paula L., Seymour, Christopher W., Huang, David T., Kip, Kevin E.
Publicado 2022

The Staphylococcus aureus Network Adaptive Platform Trial Protocol: New Tools for an Old Foe

por Tong, Steven Y C, Mora, Jocelyn, Bowen, Asha C, Cheng, Matthew P, Daneman, Nick, Goodman, Anna L, Heriot, George S, Lee, Todd C, Lewis, Roger J, Lye, David C, Mahar, Robert K, Marsh, Julie, McGlothlin, Anna, McQuilten, Zoe, Morpeth, Susan C, Paterson, David L, Price, David J, Roberts, Jason A, Robinson, J Owen, van Hal, Sebastiaan J, Walls, Genevieve, Webb, Steve A, Whiteway, Lyn, Yahav, Dafna, Davis, Joshua S
Publicado 2022

The REMAP-CAP (Randomized Embedded Multifactorial Adaptive Platform for Community-acquired Pneumonia) Study. Rationale and Design

por Angus, Derek C., Berry, Scott, Lewis, Roger J., Al-Beidh, Farah, Arabi, Yaseen, van Bentum-Puijk, Wilma, Bhimani, Zahra, Bonten, Marc, Broglio, Kristine, Brunkhorst, Frank, Cheng, Allen C., Chiche, Jean-Daniel, De Jong, Menno, Detry, Michelle, Goossens, Herman, Gordon, Anthony, Green, Cameron, Higgins, Alisa M., Hullegie, Sebastiaan J., Kruger, Peter, Lamontagne, Francois, Litton, Edward, Marshall, John, McGlothlin, Anna, McGuinness, Shay, Mouncey, Paul, Murthy, Srinivas, Nichol, Alistair, O’Neill, Genevieve K., Parke, Rachael, Parker, Jane, Rohde, Gernot, Rowan, Kathryn, Turner, Anne, Young, Paul, Derde, Lennie, McArthur, Colin, Webb, Steven A.
Publicado 2020

The comparative effectiveness of COVID-19 monoclonal antibodies: A learning health system randomized clinical trial

por McCreary, Erin K., Bariola, J. Ryan, Minnier, Tami E., Wadas, Richard J., Shovel, Judith A., Albin, Debbie, Marroquin, Oscar C., Kip, Kevin E., Collins, Kevin, Schmidhofer, Mark, Wisniewski, Mary Kay, Nace, David A., Sullivan, Colleen, Axe, Meredith, Meyers, Russell, Weissman, Alexandra, Garrard, William, Peck-Palmer, Octavia M., Wells, Alan, Bart, Robert D., Yang, Anne, Berry, Lindsay R., Berry, Scott, Crawford, Amy M., McGlothlin, Anna, Khadem, Tina, Linstrum, Kelsey, Montgomery, Stephanie K., Ricketts, Daniel, Kennedy, Jason N., Pidro, Caroline J., Haidar, Ghady, Snyder, Graham M., McVerry, Bryan J., Yealy, Donald M., Angus, Derek C., Nakayama, Anna, Zapf, Rachel L., Kip, Paula L., Seymour, Christopher W., Huang, David T.
Publicado 2022

Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial

por Arabi, Yaseen M., Gordon, Anthony C., Derde, Lennie P. G., Nichol, Alistair D., Murthy, Srinivas, Beidh, Farah Al, Annane, Djillali, Swaidan, Lolowa Al, Beane, Abi, Beasley, Richard, Berry, Lindsay R., Bhimani, Zahra, Bonten, Marc J. M., Bradbury, Charlotte A., Brunkhorst, Frank M., Buxton, Meredith, Buzgau, Adrian, Cheng, Allen, De Jong, Menno, Detry, Michelle A., Duffy, Eamon J., Estcourt, Lise J., Fitzgerald, Mark, Fowler, Rob, Girard, Timothy D., Goligher, Ewan C., Goossens, Herman, Haniffa, Rashan, Higgins, Alisa M., Hills, Thomas E., Horvat, Christopher M., Huang, David T., King, Andrew J., Lamontagne, Francois, Lawler, Patrick R., Lewis, Roger, Linstrum, Kelsey, Litton, Edward, Lorenzi, Elizabeth, Malakouti, Salim, McAuley, Daniel F., McGlothlin, Anna, Mcguinness, Shay, McVerry, Bryan J., Montgomery, Stephanie K., Morpeth, Susan C., Mouncey, Paul R., Orr, Katrina, Parke, Rachael, Parker, Jane C., Patanwala, Asad E., Rowan, Kathryn M., Santos, Marlene S., Saunders, Christina T., Seymour, Christopher W., Shankar-Hari, Manu, Tong, Steven Y. C., Turgeon, Alexis F., Turner, Anne M., Van de Veerdonk, Frank Leo, Zarychanski, Ryan, Green, Cameron, Berry, Scott, Marshall, John C., McArthur, Colin, Angus, Derek C., Webb, Steven A.
Publicado 2021