Differential binding affinity of mutated peptides for MHC class I is a predictor of survival in advanced lung cancer and melanoma

por Ghorani, E, Rosenthal, R, McGranahan, N, Reading, J L, Lynch, M, Peggs, K S, Swanton, C, Quezada, S A
Publicado 2018

Perspective: APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution

por Venkatesan, S, Rosenthal, R, Kanu, N, McGranahan, N, Bartek, J, Quezada, S A, Hare, J, Harris, R S, Swanton, C
Publicado 2018

Cyclin D mediates tolerance of genome-doubling in cancers with functional p53

por Crockford, A., Zalmas, L. P., Grönroos, E., Dewhurst, S. M., McGranahan, N., Cuomo, M. E., Encheva, V., Snijders, A. P., Begum, J., Purewal, S., Cerveira, J., Patel, H., Renshaw, M. J., Swanton, C.
Publicado 2017

Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macro-evolution of a double-minute chromosome

por Favero, F., McGranahan, N., Salm, M., Birkbak, N. J., Sanborn, J. Z., Benz, S. C., Becq, J., Peden, J. F., Kingsbury, Z., Grocok, R. J., Humphray, S., Bentley, D., Spencer-Dene, B., Gutteridge, A., Brada, M., Roger, S., Dietrich, P.-Y., Forshew, T., Gerlinger, M., Rowan, A., Stamp, G., Eklund, A. C., Szallasi, Z., Swanton, C.
Publicado 2015

SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair

por Kanu, N, Grönroos, E, Martinez, P, Burrell, R A, Yi Goh, X, Bartkova, J, Maya-Mendoza, A, Mistrík, M, Rowan, A J, Patel, H, Rabinowitz, A, East, P, Wilson, G, Santos, C R, McGranahan, N, Gulati, S, Gerlinger, M, Birkbak, N J, Joshi, T, Alexandrov, L B, Stratton, M R, Powles, T, Matthews, N, Bates, P A, Stewart, A, Szallasi, Z, Larkin, J, Bartek, J, Swanton, C
Publicado 2015

Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters

por Linch, M., Goh, G., Hiley, C., Shanmugabavan, Y., McGranahan, N., Rowan, A., Wong, Y. N. S., King, H., Furness, A., Freeman, A., Linares, J., Akarca, A., Herrero, J., Rosenthal, R., Harder, N., Schmidt, G., Wilson, G. A., Birkbak, N. J., Mitter, R., Dentro, S., Cathcart, P., Arya, M., Johnston, E., Scott, R., Hung, M., Emberton, M., Attard, G., Szallasi, Z., Punwani, S., Quezada, S. A., Marafioti, T., Gerlinger, M., Ahmed, H. U., Swanton, C.
Publicado 2017