Development of a new model system to dissect isoform specific Akt signalling in adipocytes

por Kajno, Esi, McGraw, Timothy E., Gonzalez, Eva
Publicado 2015

GLUT4 Is Sorted to Vesicles Whose Accumulation Beneath and Insertion into the Plasma Membrane Are Differentially Regulated by Insulin and Selectively Affected by Insulin Resistance

por Xiong, Wenyong, Jordens, Ingrid, Gonzalez, Eva, McGraw, Timothy E.
Publicado 2010

Anorexia and Impaired Glucose Metabolism in Mice With Hypothalamic Ablation of Glut4 Neurons

por Ren, Hongxia, Lu, Taylor Y., McGraw, Timothy E., Accili, Domenico
Publicado 2015

Regulation of PD-L1 Trafficking from Synthesis to Degradation

por Lemma, Eyoel Yemanaberhan, Letian, Anudari, Altorki, Nasser K., McGraw, Timothy E.
Publicado 2023

SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes

por Bruno, Joanne, Brumfield, Alexandria, Chaudhary, Natasha, Iaea, David, McGraw, Timothy E.
Publicado 2016

Insulin-regulated Aminopeptidase Is a Key Regulator of GLUT4 Trafficking by Controlling the Sorting of GLUT4 from Endosomes to Specialized Insulin-regulated Vesicles

por Jordens, Ingrid, Molle, Dorothee, Xiong, Wenyong, Keller, Susanna R., McGraw, Timothy E.
Publicado 2010

Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs

por Sadacca, L. Amanda, Bruno, Joanne, Wen, Jennifer, Xiong, Wenyong, McGraw, Timothy E.
Publicado 2013

Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake

por Beg, Muheeb, Abdullah, Nazish, Thowfeik, Fathima Shazna, Altorki, Nasser K, McGraw, Timothy E
Publicado 2017

Insulin-promoted mobilization of GLUT4 from a perinuclear storage site requires RAB10

por Brumfield, Alexandria, Chaudhary, Natasha, Molle, Dorothee, Wen, Jennifer, Graumann, Johannes, McGraw, Timothy E.
Publicado 2021

An Endocytosed TGN38 Chimeric Protein Is Delivered to the TGN after Trafficking through the Endocytic Recycling Compartment in CHO Cells

por Ghosh, Richik N., Mallet, William G., Soe, Thwe T., McGraw, Timothy E., Maxfield, Frederick R.
Publicado 1998

Proximity proteome mapping reveals PD-L1-dependent pathways disrupted by anti-PD-L1 antibody specifically in EGFR-mutant lung cancer cells

por Letian, Anudari, Lemma, Eyoel Yemanaberhan, Cavaliere, Paola, Dephoure, Noah, Altorki, Nasser K., McGraw, Timothy E.
Publicado 2023

Defective insulin-stimulated GLUT4 translocation in brown adipocytes induces systemic glucose homeostasis dysregulation independent of thermogenesis in female mice

por Picatoste, Belén, Yammine, Lucie, Leahey, Rosemary A., Soares, David, Johnson, Emma F., Cohen, Paul, McGraw, Timothy E.
Publicado 2021

Global evolution of the tumor microenvironment associated with progression from preinvasive invasive to invasive human lung adenocarcinoma

por Altorki, Nasser K., Borczuk, Alain C., Harrison, Sebron, Groner, Lauren K., Bhinder, Bhavneet, Mittal, Vivek, Elemento, Olivier, McGraw, Timothy E.
Publicado 2022

Spatiotemporal regulation of GIPR signaling impacts glucose homeostasis as revealed in studies of a common GIPR variant

por Yammine, Lucie, Picatoste, Belén, Abdullah, Nazish, Leahey, Rosemary A., Johnson, Emma F., Gómez-Banoy, Nicolás, Rosselot, Carolina, Wen, Jennifer, Hossain, Tahmina, Goncalves, Marcus D., Lo, James C., Garcia-Ocaña, Adolfo, McGraw, Timothy E.
Publicado 2023

TIMP1 is an early biomarker for detection and prognosis of lung cancer

por Dantas, Ezequiel, Murthy, Anirudh, Ahmed, Tanvir, Ahmed, Mujmmail, Ramsamooj, Shakti, Hurd, Maurice A., Lam, Tiffany, Malbari, Murtaza, Agrusa, Christopher, Elemento, Olivier, Zhang, Chen, Pappin, Darryl J., McGraw, Timothy E., Stiles, Brendon M., Altorki, Nasser K., Goncalves, Marcus D.
Publicado 2023

Deficiency of metabolic regulator PKM2 activates the pentose phosphate pathway and generates TCF1+ progenitor CD8+ T cells to improve checkpoint blockade

por Markowitz, Geoffrey J., Ban, Yi, Tavarez, Diamile A., Yoffe, Liron, Podaza, Enrique, He, Yongfeng, Martin, Mitchell T., Crowley, Michael J. P., Sandoval, Tito A., Gao, Dingcheng, Martin, M. Laura, Elemento, Olivier, Cubillos-Ruiz, Juan R., McGraw, Timothy E., Altorki, Nasser K., Mittal, Vivek
Publicado 2023

Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance

por Vazirani, Reema P., Verma, Akanksha, Sadacca, L. Amanda, Buckman, Melanie S., Picatoste, Belen, Beg, Muheeb, Torsitano, Christopher, Bruno, Joanne H., Patel, Rajesh T., Simonyte, Kotryna, Camporez, Joao P., Moreira, Gabriela, Falcone, Domenick J., Accili, Domenico, Elemento, Olivier, Shulman, Gerald I., Kahn, Barbara B., McGraw, Timothy E.
Publicado 2016

Tumor-intrinsic IRE1α signaling controls protective immunity in lung cancer

por Crowley, Michael J. P., Bhinder, Bhavneet, Markowitz, Geoffrey J., Martin, Mitchell, Verma, Akanksha, Sandoval, Tito A., Chae, Chang-Suk, Yomtoubian, Shira, Hu, Yang, Chopra, Sahil, Tavarez, Diamile A., Giovanelli, Paolo, Gao, Dingcheng, McGraw, Timothy E., Altorki, Nasser K., Elemento, Olivier, Cubillos-Ruiz, Juan R., Mittal, Vivek
Publicado 2023