Mitochondrial Dysfunction and the Aging Immune System

por McGuire, Peter J.
Publicado 2019

A New Mouse Model of Mild Ornithine Transcarbamylase Deficiency (spf-j) Displays Cerebral Amino Acid Perturbations at Baseline and upon Systemic Immune Activation

por Tarasenko, Tatyana N., Rosas, Odrick R., Singh, Larry N., Kristaponis, Kara, Vernon, Hilary, McGuire, Peter J.
Publicado 2015

Short report: Vaccine attitudes in the age of COVID-19 for a population of children with mitochondrial disease()()

por Gordon-Lipkin, Eliza, Marcum, Christopher Steven, Kruk, Shannon, Thompson, Elizabeth, Yeske, Philip, Martin, Lori, McGuire, Peter J
Publicado 2022

Liver-Directed Adeno-Associated Virus Serotype 8 Gene Transfer Rescues a Lethal Murine Model of Citrullinemia Type 1

por Chandler, Randy J., Tarasenko, Tatiana N., Cusmano-Ozog, Kristina, Sun, Qin, Sutton, V. Reid, Venditti, Charles P., McGuire, Peter J.
Publicado 2013

Pyruvate dehydrogenase complex integrates the metabolome and epigenome in memory T cell differentiation in vitro

por Tarasenko, Tatiana N., Banerjee, Payal, Gomez-Rodriguez, Julio, Gildea, Derek, Zhang, Suiyuan, Wolfsberg, Tyra, Jenkins, Lisa M., McGuire, Peter J.
Publicado 2023

Undiagnosed COVID-19 in households with a child with mitochondrial disease

por Gordon-Lipkin, Eliza M., Marcum, Christopher, Kruk, Shannon, Thompson, Elizabeth, Kelly, Sophie E.M., Kalish, Heather, Sadtler, Kaitlyn, McGuire, Peter J.
Publicado 2022

Risk mitigation behaviors to prevent infection in the mitochondrial disease community during the COVID-19 pandemic

por Gordon-Lipkin, Eliza, Kruk, Shannon, Thompson, Elizabeth, Yeske, Philip, Martin, Lori, Hirano, Michio, Cohen, Bruce H., Marcum, Christopher Steven, McGuire, Peter J.
Publicado 2021

Acute metabolic decompensation due to influenza in a mouse model of ornithine transcarbamylase deficiency

por McGuire, Peter J., Tarasenko, Tatiana N., Wang, Tony, Levy, Ezra, Zerfas, Patricia M., Moran, Thomas, Lee, Hye Seung, Bequette, Brian J., Diaz, George A.
Publicado 2014

Comprehensive profiling of the human viral exposome in households containing an at‐risk child with mitochondrial disease during the 2020–2021 COVID‐19 pandemic

por Gordon‐Lipkin, Eliza M., Marcum, Christopher S., Kruk, Shannon, Thompson, Elizabeth, Kelly, Sophie E. M., Kalish, Heather, Bellusci, Lorenza, Khurana, Surender, Sadtler, Kaitlyn, McGuire, Peter J.
Publicado 2022

Mitochondrial disease disrupts hepatic allostasis and lowers the threshold for immune-mediated liver toxicity

por Jestin, Maxim, Kapnick, Senta M., Tarasenko, Tatyana N., Burke, Cassidy T., Zerfas, Patricia M., Diaz, Francisca, Vernon, Hilary, Singh, Larry N., Sokol, Ronald J., McGuire, Peter J.
Publicado 2020

Inflammatory and interferon gene expression signatures in patients with mitochondrial disease

por Warren, Emily, Gordon-Lipkin, Eliza M., Cheung, Foo, Chen, Jinguo, Mukherjee, Amrita, Apps, Richard, Tsang, John S., Jetmore, Jillian, Kruk, Shannon, Lei, Yuanjiu, West, A. Phillip, McGuire, Peter J.
Publicado 2023

Primary oxidative phosphorylation defects lead to perturbations in the human B cell repertoire

por Gordon-Lipkin, Eliza M., Banerjee, Payal, Franco, Jose Luis Marin, Tarasenko, Tatiana, Kruk, Shannon, Thompson, Elizabeth, Gildea, Derek E., Zhang, Suiyuan, Wolfsberg, Tyra G., Flegel, Willy A., McGuire, Peter J.
Publicado 2023

Inflammatory and interferon gene expression signatures in patients with mitochondrial disease

por Warren, Emily B., Gordon-Lipkin, Eliza M., Cheung, Foo, Chen, Jinguo, Mukherjee, Amrita, Apps, Richard, Tsang, John S., Jetmore, Jillian, Schlein, Melissa L., Kruk, Shannon, Lei, Yuanjiu, West, A. Phillip, McGuire, Peter J.
Publicado 2023

IFNγ regulates NAD(+) metabolism to promote the respiratory burst in human monocytes

por McCann, Katelyn J., Christensen, Stephen M., Colby, Devon H., McGuire, Peter J., Myles, Ian A., Zerbe, Christa S., Dalgard, Clifton L., Sukumar, Gauthaman, Leonard, Warren J., McCormick, Beth A., Holland, Steven M.
Publicado 2022

B cell receptor isotypes differentially associate with cell signaling, kinetics, and outcome in chronic lymphocytic leukemia

por Mazzarello, Andrea N., Gentner-Göbel, Eva, Dühren-von Minden, Marcus, Tarasenko, Tatyana N., Nicolò, Antonella, Ferrer, Gerardo, Vergani, Stefano, Liu, Yun, Bagnara, Davide, Rai, Kanti R., Burger, Jan A., McGuire, Peter J., Maity, Palash C., Jumaa, Hassan, Chiorazzi, Nicholas
Publicado 2022

PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8(+) T cells at the expense of central memory

por Cannons, Jennifer L., Villarino, Alejandro V., Kapnick, Senta M., Preite, Silvia, Shih, Han-Yu, Gomez-Rodriguez, Julio, Kaul, Zenia, Shibata, Hirofumi, Reilley, Julie M., Huang, Bonnie, Handon, Robin, McBain, Ian T., Gossa, Selamawit, Wu, Tuoqi, Su, Helen C., McGavern, Dorian B., O’Shea, John J., McGuire, Peter J., Uzel, Gulbu, Schwartzberg, Pamela L.
Publicado 2021