Protein interacting with C kinase (PICK1) is a suppressor of spinocerebellar ataxia 3-associated neurodegeneration in Drosophila

por McGurk, Leeanne, Bonini, Nancy M.
Publicado 2012

TDP-43, a protein central to amyotrophic lateral sclerosis, is destabilized by tankyrase-1 and -2

por McGurk, Leeanne, Rifai, Olivia M., Bonini, Nancy M.
Publicado 2020

Poly(ADP-ribose) Engages the TDP-43 Nuclear-Localization Sequence to Regulate Granulo-Filamentous Aggregation

por McGurk, Leeanne, Gomes, Edward, Guo, Lin, Shorter, James, Bonini, Nancy M.
Publicado 2018

Three-Dimensional Imaging of Drosophila melanogaster

por McGurk, Leeanne, Morrison, Harris, Keegan, Liam P., Sharpe, James, O'Connell, Mary A.
Publicado 2007

The RGS gene loco is essential for male reproductive system differentiation in Drosophila melanogaster

por McGurk, Leeanne, Pathirana, Stephen, Rothwell, Kathleen, Trimbuch, Thorsten, Colombini, Paolo, Yu, Fengwei, Chia, William, Bownes, Mary
Publicado 2008

Editing independent effects of ADARs on the miRNA/siRNA pathways

por Heale, Bret S E, Keegan, Liam P, McGurk, Leeanne, Michlewski, Gracjan, Brindle, James, Stanton, Chloe M, Caceres, Javier F, O'Connell, Mary A
Publicado 2009

Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy

por Khan, Anzer, Paro, Simona, McGurk, Leeanne, Sambrani, Nagraj, Hogg, Marion C., Brindle, James, Pennetta, Giuseppa, Keegan, Liam P., O’Connell, Mary A.
Publicado 2020

Toxicity of pathogenic ataxin-2 in Drosophila shows dependence on a pure CAG repeat sequence

por McGurk, Leeanne, Rifai, Olivia M, Shcherbakova, Oksana, Perlegos, Alexandra E, Byrns, China N, Carranza, Faith R, Zhou, Henry W, Kim, Hyung-Jun, Zhu, Yongqing, Bonini, Nancy M
Publicado 2021

Therapeutic modulation of eIF2α-phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models

por Kim, Hyung-Jun, Raphael, Alya R., LaDow, Eva S., McGurk, Leeanne, Weber, Ross, Trojanowski, John Q., Lee, Virginia M.-Y., Finkbeiner, Steven, Gitler, Aaron D., Bonini, Nancy M.
Publicado 2013

Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

por Deng, Patricia, Khan, Anzer, Jacobson, Dionna, Sambrani, Nagraj, McGurk, Leeanne, Li, Xianghua, Jayasree, Aswathy, Hejatko, Jan, Shohat-Ophir, Galit, O’Connell, Mary A., Li, Jin Billy, Keegan, Liam P.
Publicado 2020

Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology

por François-Moutal, Liberty, Scott, David Donald, Ambrose, Andrew J., Zerio, Christopher J., Rodriguez-Sanchez, Marina, Dissanayake, Kumara, May, Danielle G., Carlson, Jacob M., Barbieri, Edward, Moutal, Aubin, Roux, Kyle J., Shorter, James, Khanna, Rajesh, Barmada, Sami J., McGurk, Leeanne, Khanna, May
Publicado 2022