Cellular models of Batten disease

por Minnis, Christopher J., Thornton, Christopher D., FitzPatrick, Lorna M., McKay, Tristan R.
Publicado 2020

Shed syndecan-2 inhibits angiogenesis

por De Rossi, Giulia, Evans, Alun R., Kay, Emma, Woodfin, Abigail, McKay, Tristan R., Nourshargh, Sussan, Whiteford, James R.
Publicado 2014

Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes

por Tew, Simon R., Peffers, Mandy J., McKay, Tristan R., Lowe, Emma T., Khan, Wasim S., Hardingham, Timothy E., Clegg, Peter D.
Publicado 2009

Perinatal Gene Transfer to the Liver

por McKay, Tristan R, Rahim, Ahad A, Buckley, Suzanne M.K, Ward, Natalie J, Chan, Jerry K.Y, Howe, Steven J, Waddington, Simon N
Publicado 2011

Evidence for Contribution of CD4+CD25+ Regulatory T Cells in Maintaining Immune Tolerance to Human Factor IX following Perinatal Adenovirus Vector Delivery

por Nivsarkar, Megha S., Buckley, Suzanne M. K., Parker, Alan L., Perocheau, Dany, McKay, Tristan R., Rahim, Ahad A., Howe, Steven J., Waddington, Simon N.
Publicado 2015

Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice

por Delhove, Juliette M. K. M., Buckley, Suzanne M. K., Perocheau, Dany P., Karda, Rajvinder, Arbuthnot, Patrick, Henderson, Neil C., Waddington, Simon N., McKay, Tristan R.
Publicado 2017

A functional human motor unit platform engineered from human embryonic stem cells and immortalized skeletal myoblasts

por Abd Al Samid, Marwah, McPhee, Jamie S, Saini, Jasdeep, McKay, Tristan R, Fitzpatrick, Lorna M, Mamchaoui, Kamel, Bigot, Anne, Mouly, Vincent, Butler-Browne, Gillian, Al-Shanti, Nasser
Publicado 2018

Ajmaline blocks I(Na) and I(Kr) without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters

por Miller, Duncan C., Harmer, Stephen C., Poliandri, Ariel, Nobles, Muriel, Edwards, Elizabeth C., Ware, James S., Sharp, Tyson V., McKay, Tristan R., Dunkel, Leo, Lambiase, Pier D., Tinker, Andrew
Publicado 2017

Cigarette smoke extract profoundly suppresses TNFα-mediated proinflammatory gene expression through upregulation of ATF3 in human coronary artery endothelial cells

por Teasdale, Jack E., Hazell, Georgina G. J., Peachey, Alasdair M. G., Sala-Newby, Graciela B., Hindmarch, Charles C. T., McKay, Tristan R., Bond, Mark, Newby, Andrew C., White, Stephen J.
Publicado 2017

Antiproliferative and Antimigratory Effects of a Novel YAP–TEAD Interaction Inhibitor Identified Using in Silico Molecular Docking

por Smith, Sarah A., Sessions, Richard B., Shoemark, Deborah K., Williams, Christopher, Ebrahimighaei, Reza, McNeill, Madeleine C., Crump, Matthew P., McKay, Tristan R., Harris, Gemma, Newby, Andrew C., Bond, Mark
Publicado 2019

Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy

por Vink, Conrad A., Counsell, John R., Perocheau, Dany P., Karda, Rajvinder, Buckley, Suzanne M.K., Brugman, Martijn H., Galla, Melanie, Schambach, Axel, McKay, Tristan R., Waddington, Simon N., Howe, Steven J.
Publicado 2017

NF-κB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program

por FitzPatrick, Lorna M., Hawkins, Kate E., Delhove, Juliette M.K.M., Fernandez, Emilio, Soldati, Chiara, Bullen, Louise F., Nohturfft, Axel, Waddington, Simon N., Medina, Diego L., Bolaños, Juan P., McKay, Tristan R.
Publicado 2018

An episomal DNA vector platform for the persistent genetic modification of pluripotent stem cells and their differentiated progeny

por Roig-Merino, Alicia, Urban, Manuela, Bozza, Matthias, Peterson, Julia D., Bullen, Louise, Büchler-Schäff, Marleen, Stäble, Sina, van der Hoeven, Franciscus, Müller-Decker, Karin, McKay, Tristan R., Milsom, Michael D., Harbottle, Richard P.
Publicado 2021

Continual conscious bioluminescent imaging in freely moving somatotransgenic mice

por Karda, Rajvinder, Perocheau, Dany P., Suff, Natalie, Ng, Joanne, Delhove, Juliette M. K. M., Buckley, Suzanne M. K., Richards, Samantha, Counsell, John R., Hagberg, Henrik, Johnson, Mark R., McKay, Tristan R., Waddington, Simon N.
Publicado 2017

Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors

por Thornton, Christopher D., Fielding, Stuart, Karbowniczek, Kinga, Roig-Merino, Alicia, Burrows, Alysha E., FitzPatrick, Lorna M., Sharaireh, Aseel, Tite, John P., Mole, Sara E., Harbottle, Richard P., Caproni, Lisa J., McKay, Tristan R.
Publicado 2021

NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming

por Hawkins, Kate E., Joy, Shona, Delhove, Juliette M.K.M., Kotiadis, Vassilios N., Fernandez, Emilio, Fitzpatrick, Lorna M., Whiteford, James R., King, Peter J., Bolanos, Juan P., Duchen, Michael R., Waddington, Simon N., McKay, Tristan R.
Publicado 2016

In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters

por Buckley, Suzanne M. K., Delhove, Juliette M. K. M., Perocheau, Dany P., Karda, Rajvinder, Rahim, Ahad A., Howe, Steven J., Ward, Natalie J., Birrell, Mark A., Belvisi, Maria G., Arbuthnot, Patrick, Johnson, Mark R., Waddington, Simon N., McKay, Tristan R.
Publicado 2015

An In Vitro Whole-Organ Liver Engineering for Testing of Genetic Therapies

por Lorvellec, Maëlle, Pellegata, Alessandro Filippo, Maestri, Alice, Turchetta, Chiara, Alvarez Mediavilla, Elena, Shibuya, Soichi, Jones, Brendan, Scottoni, Federico, Perocheau, Dany P., Cozmescu, Andrei Claudiu, Delhove, Juliette M., Kysh, Daniel, Gjinovci, Asllan, Counsell, John R., Heywood, Wendy E., Mills, Kevin, McKay, Tristan R., De Coppi, Paolo, Gissen, Paul
Publicado 2020

Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis

por Lopez-Fabuel, Irene, Garcia-Macia, Marina, Buondelmonte, Costantina, Burmistrova, Olga, Bonora, Nicolo, Alonso-Batan, Paula, Morant-Ferrando, Brenda, Vicente-Gutierrez, Carlos, Jimenez-Blasco, Daniel, Quintana-Cabrera, Ruben, Fernandez, Emilio, Llop, Jordi, Ramos-Cabrer, Pedro, Sharaireh, Aseel, Guevara-Ferrer, Marta, Fitzpatrick, Lorna, Thompton, Christopher D., McKay, Tristan R., Storch, Stephan, Medina, Diego L., Mole, Sara E., Fedichev, Peter O., Almeida, Angeles, Bolaños, Juan P.
Publicado 2022

A HIF–LIMD1 negative feedback mechanism mitigates the pro‐tumorigenic effects of hypoxia

por Foxler, Daniel E, Bridge, Katherine S, Foster, John G, Grevitt, Paul, Curry, Sean, Shah, Kunal M, Davidson, Kathryn M, Nagano, Ai, Gadaleta, Emanuela, Rhys, Hefin I, Kennedy, Paul T, Hermida, Miguel A, Chang, Ting‐Yu, Shaw, Peter E, Reynolds, Louise E, McKay, Tristan R, Wang, Hsei‐Wei, Ribeiro, Paulo S, Plevin, Michael J, Lagos, Dimitris, Lemoine, Nicholas R, Rajan, Prabhakar, Graham, Trevor A, Chelala, Claude, Hodivala‐Dilke, Kairbaan M, Spendlove, Ian, Sharp, Tyson V
Publicado 2018