On the Observation of Discrete Fluorine NMR Spectra for Uridine 5′-β,γ-Fluoromethylenetriphosphate Diastereomers at Basic pH

por Hwang, Candy S., Kashemirov, Boris A., McKenna, Charles E.
Publicado 2014

Microwave-Accelerated McKenna Synthesis of Phosphonic Acids: An Investigation

por Mustafa, Dana, Overhulse, Justin M., Kashemirov, Boris A., McKenna, Charles E.
Publicado 2023

Endocytotic Uptake of Zoledronic Acid by Tubular Cells May Explain Its Renal Effects in Cancer Patients Receiving High Doses of the Compound

por Verhulst, Anja, Sun, Shuting, McKenna, Charles E., D’Haese, Patrick C.
Publicado 2015

Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies

por Seebald, Leah M., Haratipour, Pouya, Jacobs, Michaela R., Bernstein, Hannah M., Kashemirov, Boris A., McKenna, Charles E., Imperiali, Barbara
Publicado 2023

Oral microbial extracellular DNA initiates periodontitis through gingival degradation by fibroblast-derived cathepsin K in mice

por Kondo, Takeru, Okawa, Hiroko, Hokugo, Akishige, Shokeen, Bhumika, Sundberg, Oskar, Zheng, Yiying, McKenna, Charles E., Lux, Renate, Nishimura, Ichiro
Publicado 2022

Small Molecule Inhibition of SAMHD1 dNTPase by Tetramer Destabilization

por Seamon, Kyle J., Hansen, Erik C., Kadina, Anastasia P., Kashemirov, Boris A., McKenna, Charles E., Bumpus, Namandjé N., Stivers, James T.
Publicado 2014

Regeneration of Cochlear Synapses by Systemic Administration of a Bisphosphonate

por Seist, Richard, Tong, Mingjie, Landegger, Lukas D., Vasilijic, Sasa, Hyakusoku, Hiroshi, Katsumi, Sachiyo, McKenna, Charles E., Edge, Albert S. B., Stankovic, Konstantina M.
Publicado 2020

Toward more potent imidazopyridine inhibitors of Candida albicans Bdf1: Modeling the role of structural waters in selective ligand binding

por Zhou, Yingsheng, Overhulse, Justin M., Dupper, Nathan J., Guo, Yanchun, Kashemirov, Boris A., Wei, Kaiyao, Govin, Jérôme, Petosa, Carlo, McKenna, Charles E.
Publicado 2022

Transition State in DNA Polymerase β Catalysis: Rate-Limiting Chemistry Altered by Base-Pair Configuration

por Oertell, Keriann, Chamberlain, Brian T., Wu, Yue, Ferri, Elena, Kashemirov, Boris A., Beard, William A., Wilson, Samuel H., McKenna, Charles E., Goodman, Myron F.
Publicado 2014

Bisphosphonate-induced differential modulation of immune cell function in gingiva and bone marrow in vivo: Role in osteoclast-mediated NK cell activation

por Tseng, Han-Ching, Kanayama, Keiichi, Kaur, Kawaljit, Park, So-Hyun, Park, Sil, Kozlowska, Anna, Sun, Shuting, McKenna, Charles E., Nishimura, Ichiro, Jewett, Anahid
Publicado 2015

Erratum: Bisphosphonate-induced differential modulation of immune cell function in gingiva and bone marrow in vivo: Role in osteoclast-mediated NK cell activation

por Tseng, Han-Ching, Kanayama, Keiichi, Kaur, Kawaljit, Park, So-Hyun, Park, Sil, Kozlowska, Anna, Sun, Shuting, McKenna, Charles E., Nishimura, Ichiro, Jewett, Anahid
Publicado 2015

Functional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitution

por Hwang, Candy S., Xu, Liang, Wang, Wei, Ulrich, Sébastien, Zhang, Lu, Chong, Jenny, Shin, Ji Hyun, Huang, Xuhui, Kool, Eric T., McKenna, Charles E., Wang, Dong
Publicado 2016

A pre-catalytic non-covalent step governs DNA polymerase β fidelity

por Alnajjar, Khadijeh S, Krylov, Ivan S, Negahbani, Amirsoheil, Haratipour, Pouya, Kashemirov, Boris A, Huang, Ji, Mahmoud, Mariam, McKenna, Charles E, Goodman, Myron F, Sweasy, Joann B
Publicado 2019

Development of oral osteomucosal tissue constructs in vitro and localization of fluorescently-labeled bisphosphonates to hard and soft tissue

por BAE, SUSAN, SUN, SHUTING, AGHALOO, TARA, OH, JU-EUN, McKENNA, CHARLES E., KANG, MO K., SHIN, KI-HYUK, TETRADIS, SOTIRIOS, PARK, NO-HEE, KIM, REUBEN H.
Publicado 2014

A Novel Small Molecule Neurotrophin-3 Analogue Promotes Inner Ear Neurite Outgrowth and Synaptogenesis In vitro

por Kempfle, Judith S., Duro, Marlon V., Zhang, Andrea, Amador, Carolina D., Kuang, Richard, Lu, Ryan, Kashemirov, Boris A., Edge, Albert S., McKenna, Charles E., Jung, David H.
Publicado 2021

Fluorescent risedronate analogue 800CW-pRIS improves tooth extraction-associated abnormal wound healing in zoledronate-treated mice

por Okawa, Hiroko, Kondo, Takeru, Hokugo, Akishige, Cherian, Philip, Sundberg, Oskar, Campagna, Jesus J., Kashemirov, Boris A., John, Varghese, Sun, Shuting, Ebetino, Frank H., McKenna, Charles E., Nishimura, Ichiro
Publicado 2022

Phosphonocarboxylates Inhibit the Second Geranylgeranyl Addition by Rab Geranylgeranyl Transferase

por Baron, Rudi A., Tavaré, Richard, Figueiredo, Ana C., Błażewska, Katarzyna M., Kashemirov, Boris A., McKenna, Charles E., Ebetino, Frank H., Taylor, Adam, Rogers, Michael J., Coxon, Fraser P., Seabra, Miguel C.
Publicado 2009

Mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) revealed by targeted removal of legacy bisphosphonate from jawbone using competing inert hydroxymethylene dipho...

por Okawa, Hiroko, Kondo, Takeru, Hokugo, Akishige, Cherian, Philip, Campagna, Jesus J, Lentini, Nicholas A, Sung, Eric C, Chiang, Samantha, Lin, Yi-Ling, Ebetino, Frank H, John, Varghese, Sun, Shuting, McKenna, Charles E, Nishimura, Ichiro
Publicado 2022

Real-Time Impedance-Based Monitoring of the Growth and Inhibition of Osteomyelitis Biofilm Pathogen Staphylococcus aureus Treated with Novel Bisphosphonate-Fluoroquinolone Antimicr...

por Sedghizadeh, Parish P., Cherian, Philip, Roshandel, Sahar, Tjokro, Natalia, Chen, Casey, Junka, Adam F., Hu, Eric, Neighbors, Jeffrey, Pawlak, Jacek, Russell, R. Graham G., McKenna, Charles E., Ebetino, Frank H., Sun, Shuting, Sodagar, Esmat
Publicado 2023

Paradoxical androgen receptor regulation by small molecule enantiomers

por Patsch, Katherin, Liu, Chao, Zapotoczny, Grzegorz, Sun, Yuanye, Sura, Harish, Ung, Nolan, Sun, Ren X., Haliday, Bethany, Yu, Chen, Aljehani, Mayada, Lee, Jerry S. H., Kashemirov, Boris A., Agus, David B., McKenna, Charles E., Ruderman, Daniel
Publicado 2021