Leveraging Mathematical Modeling to Quantify Pharmacokinetic and Pharmacodynamic Pathways: Equivalent Dose Metric

por McKenna, Matthew T., Weis, Jared A., Quaranta, Vito, Yankeelov, Thomas E.
Publicado 2019

Precision Medicine with Imprecise Therapy: Computational Modeling for Chemotherapy in Breast Cancer()

por McKenna, Matthew T., Weis, Jared A., Brock, Amy, Quaranta, Vito, Yankeelov, Thomas E.
Publicado 2018

Severity of Cardiovascular Disease Outcomes Among Patients With HIV Is Related to Markers of Inflammation and Coagulation

por Nordell, Anna D., McKenna, Matthew, Borges, Álvaro H., Duprez, Daniel, Neuhaus, Jacqueline, Neaton, James D.
Publicado 2014

A Predictive Mathematical Modeling Approach for the Study of Doxorubicin Treatment in Triple Negative Breast Cancer

por McKenna, Matthew T., Weis, Jared A., Barnes, Stephanie L., Tyson, Darren R., Miga, Michael I., Quaranta, Vito, Yankeelov, Thomas E.
Publicado 2017

Experimentally-driven mathematical modeling to improve combination targeted and cytotoxic therapy for HER2+ breast cancer

por Jarrett, Angela M., Shah, Alay, Bloom, Meghan J., McKenna, Matthew T., Hormuth, David A., Yankeelov, Thomas E., Sorace, Anna G.
Publicado 2019

The burden of disease and injury in the United States 1996

por Michaud, Catherine M, McKenna, Matthew T, Begg, Stephen, Tomijima, Niels, Majmudar, Meghna, Bulzacchelli, Maria T, Ebrahim, Shahul, Ezzati, Majid, Salomon, Joshua A, Gaber Kreiser, Jessica, Hogan, Mollie, Murray, Christopher JL
Publicado 2006

CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery

por Fennell, Brian J, McDonnell, Barry, Tam, Amy Sze Pui, Chang, Lijun, Steven, John, Broadbent, Ian D, Gao, Huilan, Kieras, Elizabeth, Alley, Jennifer, Luxenberg, Deborah, Edmonds, Jason, Fitz, Lori J, Miao, Wenyan, Whitters, Matthew J, Medley, Quintus G, Guo, Yongjing J, Darmanin-Sheehan, Alfredo, Autin, Bénédicte, Shúilleabháin, Deirdre Ní, Cummins, Emma, King, Amy, Krebs, Mark RH, Grace, Christopher, Hickling, Timothy P, Boisvert, Angela, Zhong, Xiaotian, McKenna, Matthew, Francis, Christopher, Olland, Stephane, Bloom, Laird, Paulsen, Janet, Somers, Will, Jensen, Allan, Lin, Laura, Finlay, William JJ, Cunningham, Orla
Publicado 2013

Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors

por Root, Adam R., Guntas, Gurkan, Katragadda, Madan, Apgar, James R., Narula, Jatin, Chang, Chew Shun, Hanscom, Sara, McKenna, Matthew, Wade, Jason, Meade, Caryl, Ma, Weijun, Guo, Yongjing, Liu, Yan, Duan, Weili, Hendershot, Claire, King, Amy C., Zhang, Yan, Sousa, Eric, Tam, Amy, Benard, Susan, Yang, Han, Kelleher, Kerry, Jin, Fang, Piche-Nicholas, Nicole, Keating, Sinead E., Narciandi, Fernando, Lawrence-Henderson, Rosemary, Arai, Maya, Stochaj, Wayne R., Svenson, Kristine, Mosyak, Lidia, Lam, Khetemcnee, Francis, Christopher, Marquette, Kimberly, Wroblewska, Liliana, Zhu, H. Lily, Sheehan, Alfredo Darmanin, LaVallie, Edward R., D’Antona, Aaron M., Betts, Alison, King, Lindsay, Rosfjord, Edward, Cunningham, Orla, Lin, Laura, Sapra, Puja, Tchistiakova, Lioudmila, Mathur, Divya, Bloom, Laird
Publicado 2021