Dysregulated Hematopoietic Stem and Progenitor Cell Activity Promotes Interleukin-23-Driven Chronic Intestinal Inflammation

por Griseri, Thibault, McKenzie, Brent S., Schiering, Chris, Powrie, Fiona
Publicado 2012

Opportunities for Treg cell therapy for the treatment of human disease

por Bluestone, Jeffrey A., McKenzie, Brent S., Beilke, Joshua, Ramsdell, Fred
Publicado 2023

GM-CSF primes cardiac inflammation in a mouse model of Kawasaki disease

por Stock, Angus T., Hansen, Jacinta A., Sleeman, Matthew A., McKenzie, Brent S., Wicks, Ian P.
Publicado 2016

Interleukin-23 drives innate and T cell–mediated intestinal inflammation

por Hue, Sophie, Ahern, Philip, Buonocore, Sofia, Kullberg, Marika C., Cua, Daniel J., McKenzie, Brent S., Powrie, Fiona, Maloy, Kevin J.
Publicado 2006

Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis

por Griseri, Thibault, Arnold, Isabelle C., Pearson, Claire, Krausgruber, Thomas, Schiering, Chris, Franchini, Fanny, Schulthess, Julie, McKenzie, Brent S., Crocker, Paul R., Powrie, Fiona
Publicado 2015

ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation

por Pearson, Claire, Thornton, Emily E, McKenzie, Brent, Schaupp, Anna-Lena, Huskens, Nicky, Griseri, Thibault, West, Nathaniel, Tung, Sim, Seddon, Benedict P, Uhlig, Holm H, Powrie, Fiona
Publicado 2016

IL-23 plays a key role in Helicobacter hepaticus–induced T cell–dependent colitis

por Kullberg, Marika C., Jankovic, Dragana, Feng, Carl G., Hue, Sophie, Gorelick, Peter L., McKenzie, Brent S., Cua, Daniel J., Powrie, Fiona, Cheever, Allen W., Maloy, Kevin J., Sher, Alan
Publicado 2006

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling

por Boniface, Katia, Bak-Jensen, Kristian S., Li, Ying, Blumenschein, Wendy M., McGeachy, Mandy J., McClanahan, Terrill K., McKenzie, Brent S., Kastelein, Robert A., Cua, Daniel J., de Waal Malefyt, René
Publicado 2009

Genetic inactivation of RIP1 kinase activity in rats protects against ischemic brain injury

por Stark, Kimberly, Goncharov, Tatiana, Varfolomeev, Eugene, Xie, Luke, Ngu, Hai, Peng, Ivan, Anderson, Keith R., Verschueren, Erik, Choi, Meena, Kirkpatrick, Donald S., Easton, Amy, Webster, Joshua D., McKenzie, Brent S., Vucic, Domagoj, Bingol, Baris
Publicado 2021

Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy

por Katschke, Kenneth J., Xi, Hongkang, Cox, Christian, Truong, Tom, Malato, Yann, Lee, Wyne P., McKenzie, Brent, Arceo, Rommel, Tao, Jianhua, Rangell, Linda, Reichelt, Mike, Diehl, Lauri, Elstrott, Justin, Weimer, Robby M, van Lookeren Campagne, Menno
Publicado 2018

Publisher Correction: Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy

por Katschke, Kenneth J., Xi, Hongkang, Cox, Christian, Truong, Tom, Malato, Yann, Lee, Wyne P., McKenzie, Brent, Arceo, Rommel, Tao, Jianhua, Rangell, Linda, Reichelt, Mike, Diehl, Lauri, Elstrott, Justin, Weimer, Robby M., van Lookeren Campagne, Menno
Publicado 2018

RIP1 kinase activity is critical for skin inflammation but not for viral propagation

por Webster, Joshua D., Kwon, Youngsu C., Park, Summer, Zhang, Hua, Corr, Nick, Ljumanovic, Nina, Adedeji, Adeyemi O., Varfolomeev, Eugene, Goncharov, Tatiana, Preston, Jessica, Santagostino, Sara F., Patel, Snahel, Xu, Min, Maher, Jonathan, McKenzie, Brent S., Vucic, Domagoj
Publicado 2020

Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins

por Whiteley, Alexandra M, Prado, Miguel A, Peng, Ivan, Abbas, Alexander R, Haley, Benjamin, Paulo, Joao A, Reichelt, Mike, Katakam, Anand, Sagolla, Meredith, Modrusan, Zora, Lee, Dong Yun, Roose-Girma, Merone, Kirkpatrick, Donald S, McKenzie, Brent S, Gygi, Steven P, Finley, Daniel, Brown, Eric J
Publicado 2017

Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease

por Cayatte, Corinne, Joyce-Shaikh, Barbara, Vega, Felix, Boniface, Katia, Grein, Jeffrey, Murphy, Erin, Blumenschein, Wendy M, Chen, Smiley, Malinao, Maria-Christina, Basham, Beth, Pierce, Robert H, Bowman, Edward P, McKenzie, Brent S, Elson, Charles O, Faubion, William A, Malefyt, Rene de Waal, Kastelein, Robert A, Cua, Daniel, McClanahan, Terrill K, Beaumont, Maribel
Publicado 2012

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis

por O'Donoghue, Robert J J, Knight, Darryl A, Richards, Carl D, Prêle, Cecilia M, Lau, Hui Ling, Jarnicki, Andrew G, Jones, Jessica, Bozinovski, Steven, Vlahos, Ross, Thiem, Stefan, McKenzie, Brent S, Wang, Bo, Stumbles, Philip, Laurent, Geoffrey J, McAnulty, Robin J, Rose-John, Stefan, Zhu, Hong Jian, Anderson, Gary P, Ernst, Matthias R, Mutsaers, Steven E
Publicado 2012

RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases

por Patel, Snahel, Webster, Joshua D., Varfolomeev, Eugene, Kwon, Youngsu C., Cheng, Jason H., Zhang, Juan, Dugger, Debra L., Wickliffe, Kate E., Maltzman, Allie, Sujatha-Bhaskar, Swathi, Bir Kohli, Pawan, Ramaswamy, Sreema, Deshmukh, Gauri, Liederer, Bianca M., Fong, Rina, Hamilton, Greg, Lupardus, Patrick, Caplazi, Patrick, Lee, Wyne P., van Lookeren Campagne, Menno, Johnson, Adam, McKenzie, Brent S., Junttila, Melissa R., Newton, Kim, Vucic, Domagoj
Publicado 2019

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus

por Brightbill, Hans D., Suto, Eric, Blaquiere, Nicole, Ramamoorthi, Nandhini, Sujatha-Bhaskar, Swathi, Gogol, Emily B., Castanedo, Georgette M., Jackson, Benjamin T., Kwon, Youngsu C., Haller, Susan, Lesch, Justin, Bents, Karin, Everett, Christine, Kohli, Pawan Bir, Linge, Sandra, Christian, Laura, Barrett, Kathy, Jaochico, Allan, Berezhkovskiy, Leonid M., Fan, Peter W., Modrusan, Zora, Veliz, Kelli, Townsend, Michael J., DeVoss, Jason, Johnson, Adam R., Godemann, Robert, Lee, Wyne P., Austin, Cary D., McKenzie, Brent S., Hackney, Jason A., Crawford, James J., Staben, Steven T., Alaoui Ismaili, Moulay H., Wu, Lawren C., Ghilardi, Nico
Publicado 2018