Epigenetic signature of N-terminal acetyltransferases: a probable mediator of immune and neuropathogenesis in HIV infection

por Sundar, Vaishnavi, McLaughlin, Jay P., Samikkannu, Thangavel
Publicado 2022

Circadian disruption and psychostimulants dysregulates plasma acute-phase proteins and circulating cell-free mitochondrial DNA

por Ramasamy, Tamizhselvi, Doke, Mayur, McLaughlin, Jay P., Samikkannu, Thangavel
Publicado 2023

HIV-1 Tat and cocaine impact mitochondrial epigenetics: effects on DNA methylation

por Doke, Mayur, Jeganathan, Venkatesh, McLaughlin, Jay P., Samikkannu, Thangavel
Publicado 2020

Sleep Disorder and Cocaine Abuse Impact Purine and Pyrimidine Nucleotide Metabolic Signatures

por Doke, Mayur, McLaughlin, Jay P., Baniasadi, Hamid, Samikkannu, Thangavel
Publicado 2022

Proteomics Profiling with SWATH-MS Quantitative Analysis of Changes in the Human Brain with HIV Infection Reveals a Differential Impact on the Frontal and Temporal Lobes

por Doke, Mayur, Ramasamy, Tamizhselvi, Sundar, Vaishnavi, McLaughlin, Jay P., Samikkannu, Thangavel
Publicado 2021

The cross-talk of HIV-1 Tat and methamphetamine in HIV-associated neurocognitive disorders

por Mediouni, Sonia, Garibaldi Marcondes, Maria Cecilia, Miller, Courtney, McLaughlin, Jay P., Valente, Susana T.
Publicado 2015

Identification and Pharmacological Characterization of a Low-Liability Antinociceptive Bifunctional MOR/DOR Cyclic Peptide

por Li, Yangmei, Eans, Shainnel O., Ganno-Sherwood, Michelle, Eliasof, Abbe, Houghten, Richard A., McLaughlin, Jay P.
Publicado 2023

HIV-1 Tat and cocaine impact astrocytic energy reservoirs and epigenetic regulation by influencing the LINC01133-hsa-miR-4726-5p-NDUFA9 axis

por Doke, Mayur, McLaughlin, Jay P., Cai, James J., Pendyala, Gurudutt, Kashanchi, Fatah, Khan, Mansoor A., Samikkannu, Thangavel
Publicado 2022

Northeast Under/graduate Research Organization for Neuroscience (NEURON): Our Thirteenth Conference for Neuroscience Trainees and Educators

por McLaughlin, Jay P., Gomes, Stacey, Seliga, Angela, Goyette, Sharon Ramos, Morrison, Amy, Reich, Christian G., Frye, Cheryl A.
Publicado 2009

Selective κ receptor partial agonist HS666 produces potent antinociception without inducing aversion after i.c.v. administration in mice

por Spetea, Mariana, Eans, Shainnel O, Ganno, Michelle L, Lantero, Aquilino, Mairegger, Michael, Toll, Lawrence, Schmidhammer, Helmut, McLaughlin, Jay P
Publicado 2017

Examination of the Novel Sigma-1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti-allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use

por Wilson, Lisa L., Eans, Shainnel O., Ramadan-Siraj, Insitar, Modica, Maria N., Romeo, Giuseppe, Intagliata, Sebastiano, McLaughlin, Jay P.
Publicado 2022

Solid-Phase Synthesis of the Bicyclic Peptide OL-CTOP Containing Two Disulfide Bridges, and an Assessment of Its In Vivo μ-Opioid Receptor Antagonism after Nasal Administration

por Rayala, Ramanjaneyulu, Tiller, Annika, Majumder, Shahayra A., Stacy, Heather M., Eans, Shainnel O., Nedovic, Aleksandra, McLaughlin, Jay P., Cudic, Predrag
Publicado 2023

Nonpeptide Small Molecule Agonist and Antagonist Original Leads for Neuropeptide FF1 and FF2 Receptors

por Journigan, V. Blair, Mésangeau, Christophe, Vyas, Neha, Eans, Shainnel O., Cutler, Stephen J., McLaughlin, Jay P., Mollereau, Catherine, McCurdy, Christopher R.
Publicado 2014

Tryptophan Substitution in CJ-15,208 (cyclo[Phe-D-Pro-Phe-Trp]) Introduces δ-Opioid Receptor Antagonism, Preventing Antinociceptive Tolerance and Stress-Induced Reinstatement of Ex...

por Scherrer, Kristen H., Eans, Shainnel O., Medina, Jessica M., Senadheera, Sanjeewa N., Khaliq, Tanvir, Murray, Thomas F., McLaughlin, Jay P., Aldrich, Jane V.
Publicado 2023

Characterization of Sigma 1 Receptor Antagonist CM-304 and Its Analog, AZ-66: Novel Therapeutics Against Allodynia and Induced Pain

por Cirino, Thomas J., Eans, Shainnel O., Medina, Jessica M., Wilson, Lisa L., Mottinelli, Marco, Intagliata, Sebastiano, McCurdy, Christopher R., McLaughlin, Jay P.
Publicado 2019

Development of New Benzylpiperazine Derivatives as σ(1) Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects

por Romeo, Giuseppe, Bonanno, Federica, Wilson, Lisa L., Arena, Emanuela, Modica, Maria N., Pittalà, Valeria, Salerno, Loredana, Prezzavento, Orazio, McLaughlin, Jay P., Intagliata, Sebastiano
Publicado 2021

Bis-Cyclic Guanidine Heterocyclic Peptidomimetics as Opioid Ligands with Mixed μ-, κ- and δ-Opioid Receptor Interactions: A Potential Approach to Novel Analgesics

por McLaughlin, Jay P., Rayala, Ramanjaneyulu, Bunnell, Ashley J., Tantak, Mukund P., Eans, Shainnel O., Nefzi, Khadija, Ganno, Michelle L., Dooley, Colette T., Nefzi, Adel
Publicado 2022

A stable isotope dilution tandem mass spectrometry method of major kavalactones and its applications

por Wang, Yi, Eans, Shainnel O., Stacy, Heather M., Narayanapillai, Sreekanth C., Sharma, Abhisheak, Fujioka, Naomi, Haddad, Linda, McLaughlin, Jay, Avery, Bonnie A., Xing, Chengguo
Publicado 2018

Phenylalanine Stereoisomers of CJ-15,208 and [d-Trp]CJ-15,208 Exhibit Distinctly Different Opioid Activity Profiles

por Brice-Tutt, Ariana C., Senadheera, Sanjeewa N., Ganno, Michelle L., Eans, Shainnel O., Khaliq, Tanvir, Murray, Thomas F., McLaughlin, Jay P., Aldrich, Jane V.
Publicado 2020

Clathrin-nanoparticles deliver BDNF to hippocampus and enhance neurogenesis, synaptogenesis and cognition in HIV/neuroAIDS mouse model

por Vitaliano, Gordana D., Kim, Jae K., Kaufman, Marc J., Adam, Christopher W., Zeballos, Gonzalo, Shanmugavadivu, Abinaya, Subburaju, Sivan, McLaughlin, Jay P., Lukas, Scott E., Vitaliano, Franco
Publicado 2022