Glucagon-like Peptide-1 receptor Tie2+ cells are essential for the cardioprotective actions of liraglutide in mice with experimental myocardial infarction

por McLean, Brent A., Wong, Chi Kin, Kabir, M Golam, Drucker, Daniel J.
Publicado 2022

Differential importance of endothelial and hematopoietic cell GLP-1Rs for cardiometabolic versus hepatic actions of semaglutide

por McLean, Brent A., Wong, Chi Kin, Kaur, Kiran Deep, Seeley, Randy J., Drucker, Daniel J.
Publicado 2021

Genetic disruption of the Gipr in Apoe(−/−) mice promotes atherosclerosis

por Pujadas, Gemma, Baggio, Laurie L., Kaur, Kiran Deep, McLean, Brent A., Cao, Xiemin, Drucker, Daniel J.
Publicado 2022

Loss of PI3Kα Mediates Protection From Myocardial Ischemia–Reperfusion Injury Linked to Preserved Mitochondrial Function

por Zhabyeyev, Pavel, McLean, Brent, Bassiouni, Wesam, Valencia, Robert, Paul, Manish, Darwesh, Ahmed M., Seubert, John M., Hazra, Saugata, Oudit, Gavin Y.
Publicado 2023

PI3Kα Pathway Inhibition With Doxorubicin Treatment Results in Distinct Biventricular Atrophy and Remodeling With Right Ventricular Dysfunction

por McLean, Brent A., Patel, Vaibhav B., Zhabyeyev, Pavel, Chen, Xueyi, Basu, Ratnadeep, Wang, Faqi, Shah, Saumya, Vanhaesebroeck, Bart, Oudit, Gavin Y.
Publicado 2019

ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity

por Patel, Vaibhav B., Mori, Jun, McLean, Brent A., Basu, Ratnadeep, Das, Subhash K., Ramprasath, Tharmarajan, Parajuli, Nirmal, Penninger, Josef M., Grant, Maria B., Lopaschuk, Gary D., Oudit, Gavin Y.
Publicado 2016

The autonomic nervous system and cardiac GLP-1 receptors control heart rate in mice

por Baggio, Laurie L., Ussher, John R., McLean, Brent A., Cao, Xiemin, Kabir, M. Golam, Mulvihill, Erin E., Mighiu, Alexandra S., Zhang, Hangjun, Ludwig, Andreas, Seeley, Randy J., Heximer, Scott P., Drucker, Daniel J.
Publicado 2017

Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy

por Das, Subhash K., Wang, Wang, Zhabyeyev, Pavel, Basu, Ratnadeep, McLean, Brent, Fan, Dong, Parajuli, Nirmal, DesAulniers, Jessica, Patel, Vaibhav B., Hajjar, Roger J., Dyck, Jason R. B., Kassiri, Zamaneh, Oudit, Gavin Y.
Publicado 2015

Loss of Apelin Exacerbates Myocardial Infarction Adverse Remodeling and Ischemia‐reperfusion Injury: Therapeutic Potential of Synthetic Apelin Analogues

por Wang, Wang, McKinnie, Shaun M.K., Patel, Vaibhav B., Haddad, George, Wang, Zuocheng, Zhabyeyev, Pavel, Das, Subhash K., Basu, Ratnadeep, McLean, Brent, Kandalam, Vijay, Penninger, Josef M., Kassiri, Zamaneh, Vederas, John C., Murray, Allan G., Oudit, Gavin Y.
Publicado 2013

PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease

por Patel, Vaibhav B., Zhabyeyev, Pavel, Chen, Xueyi, Wang, Faqi, Paul, Manish, Fan, Dong, McLean, Brent A., Basu, Ratnadeep, Zhang, Pu, Shah, Saumya, Dawson, John F., Pyle, W. Glen, Hazra, Mousumi, Kassiri, Zamaneh, Hazra, Saugata, Vanhaesebroeck, Bart, McCulloch, Christopher A., Oudit, Gavin Y.
Publicado 2018