Glucagon-like Peptide-1 receptor Tie2+ cells are essential for the cardioprotective actions of liraglutide in mice with experimental myocardial infarction

por McLean, Brent A., Wong, Chi Kin, Kabir, M Golam, Drucker, Daniel J.
Publicado 2022

Differential importance of endothelial and hematopoietic cell GLP-1Rs for cardiometabolic versus hepatic actions of semaglutide

por McLean, Brent A., Wong, Chi Kin, Kaur, Kiran Deep, Seeley, Randy J., Drucker, Daniel J.
Publicado 2021

Genetic disruption of the Gipr in Apoe(−/−) mice promotes atherosclerosis

por Pujadas, Gemma, Baggio, Laurie L., Kaur, Kiran Deep, McLean, Brent A., Cao, Xiemin, Drucker, Daniel J.
Publicado 2022

PI3Kα Pathway Inhibition With Doxorubicin Treatment Results in Distinct Biventricular Atrophy and Remodeling With Right Ventricular Dysfunction

por McLean, Brent A., Patel, Vaibhav B., Zhabyeyev, Pavel, Chen, Xueyi, Basu, Ratnadeep, Wang, Faqi, Shah, Saumya, Vanhaesebroeck, Bart, Oudit, Gavin Y.
Publicado 2019

ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity

por Patel, Vaibhav B., Mori, Jun, McLean, Brent A., Basu, Ratnadeep, Das, Subhash K., Ramprasath, Tharmarajan, Parajuli, Nirmal, Penninger, Josef M., Grant, Maria B., Lopaschuk, Gary D., Oudit, Gavin Y.
Publicado 2016

The autonomic nervous system and cardiac GLP-1 receptors control heart rate in mice

por Baggio, Laurie L., Ussher, John R., McLean, Brent A., Cao, Xiemin, Kabir, M. Golam, Mulvihill, Erin E., Mighiu, Alexandra S., Zhang, Hangjun, Ludwig, Andreas, Seeley, Randy J., Heximer, Scott P., Drucker, Daniel J.
Publicado 2017

PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease

por Patel, Vaibhav B., Zhabyeyev, Pavel, Chen, Xueyi, Wang, Faqi, Paul, Manish, Fan, Dong, McLean, Brent A., Basu, Ratnadeep, Zhang, Pu, Shah, Saumya, Dawson, John F., Pyle, W. Glen, Hazra, Mousumi, Kassiri, Zamaneh, Hazra, Saugata, Vanhaesebroeck, Bart, McCulloch, Christopher A., Oudit, Gavin Y.
Publicado 2018