Clonal Evolution Revealed by Whole Genome Sequencing in a Case of Primary Myelofibrosis Transformed to Secondary Acute Myeloid Leukemia

por Engle, Elizabeth K., Fisher, Daniel A.C., Miller, Christopher A., McLellan, Michael D., Fulton, Robert S., Moore, Deborah M., Wilson, Richard K., Ley, Timothy J., Oh, Stephen T.
Publicado 2014

HPV-EM: an accurate HPV detection and genotyping EM algorithm

por Inkman, Matthew J., Jayachandran, Kay, Ellis, Thomas M., Ruiz, Fiona, McLellan, Michael D., Miller, Christopher A., Wu, Yufeng, Ojesina, Akinyemi I., Schwarz, Julie K., Zhang, Jin
Publicado 2020

HPV transcript expression affects cervical cancer response to chemoradiation

por Ruiz, Fiona J., Inkman, Matthew, Rashmi, Ramachandran, Muhammad, Naoshad, Gabriel, Nishanth, Miller, Christopher A., McLellan, Michael D., Goldstein, Michael, Markovina, Stephanie, Grigsby, Perry W., Zhang, Jin, Schwarz, Julie K.
Publicado 2021

Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif

por Hamilton, Mark P., Rajapakshe, Kimal, Hartig, Sean M., Reva, Boris, McLellan, Michael D., Kandoth, Cyriac, Ding, Li, Zack, Travis I., Gunaratne, Preethi H., Wheeler, David A., Coarfa, Cristian, McGuire, Sean E.
Publicado 2013

Clinical outcomes and differential effects of PI3K pathway mutation in obese versus non-obese patients with cervical cancer

por Grigsby, Perry, Elhammali, Adnan, Ruiz, Fiona, Markovina, Stephanie, McLellan, Michael D., Miller, Christopher A., Chundury, Anupama, Ta, Ngoc-Anh L., Rashmi, Ramachandran, Pfeifer, John D., Fulton, Robert S., DeWees, Todd, Schwarz, Julie K.
Publicado 2017

Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma

por Gutmann, David H., McLellan, Michael D., Hussain, Ibrahim, Wallis, John W., Fulton, Lucinda L., Fulton, Robert S., Magrini, Vincent, Demeter, Ryan, Wylie, Todd, Kandoth, Cyriac, Leonard, Jeffrey R., Guha, Abhijit, Miller, Christopher A., Ding, Li, Mardis, Elaine R.
Publicado 2013

BreakTrans: uncovering the genomic architecture of gene fusions

por Chen, Ken, Navin, Nicholas E, Wang, Yong, Schmidt, Heather K, Wallis, John W, Niu, Beifang, Fan, Xian, Zhao, Hao, McLellan, Michael D, Hoadley, Katherine A, Mardis, Elaine R, Ley, Timothy J, Perou, Charles M, Wilson, Richard K, Ding, Li
Publicado 2013

BreakDancer: An algorithm for high resolution mapping of genomic structural variation

por Chen, Ken, Wallis, John W., McLellan, Michael D., Larson, David E., Kalicki, Joelle M., Pohl, Craig S., McGrath, Sean D., Wendl, Michael C., Zhang, Qunyuan, Locke, Devin P., Shi, Xiaoqi, Fulton, Robert S., Ley, Timothy J., Wilson, Richard K., Ding, Li, Mardis, Elaine R.
Publicado 2009

Mutational Analysis of EGFR and Related Signaling Pathway Genes in Lung Adenocarcinomas Identifies a Novel Somatic Kinase Domain Mutation in FGFR4

por Marks, Jenifer L., McLellan, Michael D., Zakowski, Maureen F., Lash, Alex E., Kasai, Yumi, Broderick, Stephen, Sarkaria, Inderpal S., Pham, DuyKhanh, Singh, Bhuvanesh, Miner, Tracie L., Fewell, Ginger A., Fulton, Lucinda L., Mardis, Elaine R., Wilson, Richard K., Kris, Mark G., Rusch, Valerie W., Varmus, Harold, Pao, William
Publicado 2007

Systematic Discovery of Complex Indels in Human Cancers

por Ye, Kai, Wang, Jiayin, Jayasinghe, Reyka, Lameijer, Eric-Wubbo, McMichael, Joshua F., Ning, Jie, McLellan, Michael D., Xie, Mingchao, Cao, Song, Yellapantula, Venkata, Huang, Kuan-lin, Scott, Adam, Foltz, Steven, Niu, Beifang, Johnson, Kimberly J., Moed, Matthijs, Slagboom, P. Eline, Chen, Feng, Wendl, Michael C., Ding, Li
Publicado 2015

Mutational landscape and significance across 12 major cancer types

por Kandoth, Cyriac, McLellan, Michael D., Vandin, Fabio, Ye, Kai, Niu, Beifang, Lu, Charles, Xie, Mingchao, Zhang, Qunyuan, McMichael, Joshua F., Wyczalkowski, Matthew A., Leiserson, Mark D. M., Miller, Christopher A., Welch, John S., Walter, Matthew J., Wendl, Michael C., Ley, Timothy J., Wilson, Richard K., Raphael, Benjamin J., Ding, Li
Publicado 2013

Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation

por Li, Lijin, Zhang, Xiuli, Wang, Xiaoli, Kim, Samuel W., Herndon, John M., Becker-Hapak, Michelle K., Carreno, Beatriz M., Myers, Nancy B., Sturmoski, Mark A., McLellan, Michael D., Miller, Christopher A., Johanns, Tanner M., Tan, Benjamin R., Dunn, Gavin P., Fleming, Timothy P., Hansen, Ted H., Goedegebuure, S. Peter, Gillanders, William E.
Publicado 2021

Age-related cancer mutations associated with clonal hematopoietic expansion

por Xie, Mingchao, Lu, Charles, Wang, Jiayin, McLellan, Michael D., Johnson, Kimberly J., Wendl, Michael C., McMichael, Joshua F., Schmidt, Heather K., Yellapantula, Venkata, Miller, Christopher A., Ozenberger, Bradley A., Welch, John S., Link, Daniel C., Walter, Matthew J., Mardis, Elaine R., Dipersio, John F., Chen, Feng, Wilson, Richard K., Ley, Timothy J., Ding, Li
Publicado 2014

Integrated Analysis of Germline and Somatic Variants in Ovarian Cancer

por Kanchi, Krishna L., Johnson, Kimberly J., Lu, Charles, McLellan, Michael D., Leiserson, Mark D.M., Wendl, Michael C., Zhang, Qunyuan, Koboldt, Daniel C., Xie, Mingchao, Kandoth, Cyriac, McMichael, Joshua F., Wyczalkowski, Matthew A., Larson, David E., Schmidt, Heather K., Miller, Christopher A., Fulton, Robert S., Spellman, Paul T., Mardis, Elaine R., Druley, Todd E., Graubert, Timothy A., Goodfellow, Paul J., Raphael, Benjamin J., Wilson, Richard K., Ding, Li
Publicado 2014

RECURRENT MUTATIONS IN THE U2AF1 SPLICING FACTOR IN MYELODYSPLASTIC SYNDROMES

por Graubert, Timothy A., Shen, Dong, Ding, Li, Okeyo-Owuor, Theresa, Lunn, Cara L., Shao, Jin, Krysiak, Kilannin, Harris, Christopher C., Koboldt, Daniel C., Larson, David E., McLellan, Michael D., Dooling, David J., Abbott, Rachel M., Fulton, Robert S., Schmidt, Heather, Kalicki-Veizer, Joelle, O’Laughlin, Michelle, Grillot, Marcus, Baty, Jack, Heath, Sharon, Frater, John L., Nasim, Talat, Link, Daniel C., Tomasson, Michael H., Westervelt, Peter, DiPersio, John F., Mardis, Elaine R., Ley, Timothy J., Wilson, Richard K., Walter, Matthew J.
Publicado 2011

Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci

por Service, Susan K., Teslovich, Tanya M., Fuchsberger, Christian, Ramensky, Vasily, Yajnik, Pranav, Koboldt, Daniel C., Larson, David E., Zhang, Qunyuan, Lin, Ling, Welch, Ryan, Ding, Li, McLellan, Michael D., O'Laughlin, Michele, Fronick, Catrina, Fulton, Lucinda L., Magrini, Vincent, Swift, Amy, Elliott, Paul, Jarvelin, Marjo-Riitta, Kaakinen, Marika, McCarthy, Mark I., Peltonen, Leena, Pouta, Anneli, Bonnycastle, Lori L., Collins, Francis S., Narisu, Narisu, Stringham, Heather M., Tuomilehto, Jaakko, Ripatti, Samuli, Fulton, Robert S., Sabatti, Chiara, Wilson, Richard K., Boehnke, Michael, Freimer, Nelson B.
Publicado 2014

Proteogenomics connects somatic mutations to signaling in breast cancer

por Mertins, Philipp, Mani, D. R., Ruggles, Kelly V., Gillette, Michael A., Clauser, Karl R., Wang, Pei, Wang, Xianlong, Qiao, Jana W., Cao, Song, Petralia, Francesca, Kawaler, Emily, Mundt, Filip, Krug, Karsten, Tu, Zhidong, Lei, Jonathan T., Gatza, Michael L., Wilkerson, Matthew, Perou, Charles M., Yellapantula, Venkata, Huang, Kuan-lin, Lin, Chenwei, McLellan, Michael D., Yan, Ping, Davies, Sherri R., Townsend, R. Reid, Skates, Steven J., Wang, Jing, Zhang, Bing, Kinsinger, Christopher R., Mesri, Mehdi, Rodriguez, Henry, Ding, Li, Paulovich, Amanda G., Fenyo, David, Ellis, Matthew J., Carr, Steven A.
Publicado 2016

Clonal evolution in relapsed acute myeloid leukemia revealed by whole genome sequencing

por Ding, Li, Ley, Timothy J., Larson, David E., Miller, Christopher A., Koboldt, Daniel C., Welch, John S., Ritchey, Julie K., Young, Margaret A., Lamprecht, Tamara, McLellan, Michael D., McMichael, Joshua F., Wallis, John W., Lu, Charles, Shen, Dong, Harris, Christopher C., Dooling, David J., Fulton, Robert S., Fulton, Lucinda L., Chen, Ken, Schmidt, Heather, Kalicki-Veizer, Joelle, Magrini, Vincent J., Cook, Lisa, McGrath, Sean D., Vickery, Tammi L., Wendl, Michael C., Heath, Sharon, Watson, Mark A., Link, Daniel C., Tomasson, Michael H., Shannon, William D., Payton, Jacqueline E., Kulkarni, Shashikant, Westervelt, Peter, Walter, Matthew J., Graubert, Timothy A., Mardis, Elaine R., Wilson, Richard K., DiPersio, John F.
Publicado 2012

DNA sequencing of a cytogenetically normal acute myeloid leukemia genome

por Ley, Timothy J, Mardis, Elaine R, Ding, Li, Fulton, Bob, McLellan, Michael D, Chen, Ken, Dooling, David, Dunford-Shore, Brian H, McGrath, Sean, Hickenbotham, Matthew, Cook, Lisa, Abbott, Rachel, Larson, David E, Koboldt, Dan C, Pohl, Craig, Smith, Scott, Hawkins, Amy, Abbott, Scott, Locke, Devin, Hillier, LaDeana W, Miner, Tracie, Fulton, Lucinda, Magrini, Vincent, Wylie, Todd, Glasscock, Jarret, Conyers, Joshua, Sander, Nathan, Shi, Xiaoqi, Osborne, John R, Minx, Patrick, Gordon, David, Chinwalla, Asif, Zhao, Yu, Ries, Rhonda E, Payton, Jacqueline E, Westervelt, Peter, Tomasson, Michael H, Watson, Mark, Baty, Jack, Ivanovich, Jennifer, Heath, Sharon, Shannon, William D, Nagarajan, Rakesh, Walter, Matthew J, Link, Daniel C, Graubert, Timothy A, DiPersio, John F, Wilson, Richard K
Publicado 2008

Patterns and functional implications of rare germline variants across 12 cancer types

por Lu, Charles, Xie, Mingchao, Wendl, Michael C., Wang, Jiayin, McLellan, Michael D., Leiserson, Mark D. M., Huang, Kuan-lin, Wyczalkowski, Matthew A., Jayasinghe, Reyka, Banerjee, Tapahsama, Ning, Jie, Tripathi, Piyush, Zhang, Qunyuan, Niu, Beifang, Ye, Kai, Schmidt, Heather K., Fulton, Robert S., McMichael, Joshua F., Batra, Prag, Kandoth, Cyriac, Bharadwaj, Maheetha, Koboldt, Daniel C., Miller, Christopher A., Kanchi, Krishna L., Eldred, James M., Larson, David E., Welch, John S., You, Ming, Ozenberger, Bradley A., Govindan, Ramaswamy, Walter, Matthew J., Ellis, Matthew J., Mardis, Elaine R., Graubert, Timothy A., Dipersio, John F., Ley, Timothy J., Wilson, Richard K., Goodfellow, Paul J., Raphael, Benjamin J., Chen, Feng, Johnson, Kimberly J., Parvin, Jeffrey D., Ding, Li
Publicado 2015