Disease-associated oligodendrocyte signatures in neurodegenerative disease: the known and unknown

por Schuster, Kristen H., McLoughlin, Hayley S.
Publicado 2023

Pathogenetic Mechanisms Underlying Spinocerebellar Ataxia Type 3 Are Altered in Primary Oligodendrocyte Culture

por Schuster, Kristen H., Putka, Alexandra F., McLoughlin, Hayley S.
Publicado 2022

Myelinating Glia: Potential Therapeutic Targets in Polyglutamine Spinocerebellar Ataxias

por Putka, Alexandra F., Mato, Juan P., McLoughlin, Hayley S.
Publicado 2023

Loss of the Spinocerebellar Ataxia type 3 disease protein ATXN3 alters transcription of multiple signal transduction pathways

por Zeng, Li, Zhang, Dapeng, McLoughlin, Hayley S., Zalon, Annie J., Aravind, L., Paulson, Henry L.
Publicado 2018

Regional sex differences in neurochemical profiles of healthy mice measured by magnetic resonance spectroscopy at 9.4 tesla

por Tkáč, Ivan, Xie, Tiankai, Shah, Nitya, Larson, Sarah, Dubinsky, Janet M., Gomez-Pastor, Rocio, McLoughlin, Hayley S., Orr, Harry T., Eberly, Lynn E., Öz, Gülin
Publicado 2023

Evaluation of Antisense Oligonucleotides Targeting ATXN3 in SCA3 Mouse Models

por Moore, Lauren R., Rajpal, Gautam, Dillingham, Ian T., Qutob, Maya, Blumenstein, Kate G., Gattis, Danielle, Hung, Gene, Kordasiewicz, Holly B., Paulson, Henry L., McLoughlin, Hayley S.
Publicado 2017

Disease-associated oligodendrocyte signatures are spatiotemporally dysregulated in spinocerebellar ataxia type 3

por Schuster, Kristen H., DiFranco, Danielle M., Putka, Alexandra F., Mato, Juan P., Jarrah, Sabrina I., Stec, Nicholas R., Sundararajan, Vikram O., McLoughlin, Hayley S.
Publicado 2023

Blood neurofilament light chain levels are associated with disease progression in a transgenic SCA3 mouse model

por Mengel, David, Wellik, Isabel G., Schuster, Kristen H., Jarrah, Sabrina I., Wacker, Madeleine, Ashraf, Naila S., Öz, Gülin, Synofzik, Matthis, do Carmo Costa, Maria, McLoughlin, Hayley S.
Publicado 2023

Blood levels of neurofilament light are associated with disease progression in a mouse model of spinocerebellar ataxia type 3

por Mengel, David, Wellik, Isabel G., Schuster, Kristen H., Jarrah, Sabrina I., Wacker, Madeleine, Ashraf, Naila S., Öz, Gülin, Synofzik, Matthis, Costa, Maria do Carmo, McLoughlin, Hayley S.
Publicado 2023

Dysregulated miR-125a promotes angiogenesis through enhanced glycolysis

por Wade, Sarah M., Ohnesorge, Nils, McLoughlin, Hayley, Biniecka, Monika, Carter, Steven P., Trenkman, Michelle, Cunningham, Clare C., McGarry, Trudy, Canavan, Mary, Kennedy, Breandán N., Veale, Douglas J., Fearon, Ursula
Publicado 2019

Purkinje-Enriched snRNA-seq in SCA7 Cerebellum Reveals Zebrin Identity Loss as a Central Feature of Polyglutamine Ataxias

por Bartelt, Luke C., Switonski, Pawel M., Adamek, Grażyna, Carvalho, Juliana, Duvick, Lisa A., Jarrah, Sabrina I., McLoughlin, Hayley S., Scoles, Daniel R., Pulst, Stefan M., Orr, Harry T., Hull, Court, Lowe, Craig B., La Spada, Albert R.
Publicado 2023

Enrichment of NPC1-deficient cells with the lipid LBPA stimulates autophagy, improves lysosomal function, and reduces cholesterol storage

por Ilnytska, Olga, Lai, Kimberly, Gorshkov, Kirill, Schultz, Mark L., Tran, Bruce Nguyen, Jeziorek, Maciej, Kunkel, Thaddeus J., Azaria, Ruth D., McLoughlin, Hayley S., Waghalter, Miriam, Xu, Yang, Schlame, Michael, Altan-Bonnet, Nihal, Zheng, Wei, Lieberman, Andrew P., Dobrowolski, Radek, Storch, Judith
Publicado 2021

Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann–Pick diseases

por Schultz, Mark L., Fawaz, Maria V., Azaria, Ruth D., Hollon, Todd C., Liu, Elaine A., Kunkel, Thaddeus J., Halseth, Troy A., Krus, Kelsey L., Ming, Ran, Morin, Emily E., McLoughlin, Hayley S., Bushart, David D., Paulson, Henry L., Shakkottai, Vikram G., Orringer, Daniel A., Schwendeman, Anna S., Lieberman, Andrew P.
Publicado 2019