Autophagy Inhibition in BRAF-Driven Cancers

por Foth, Mona, McMahon, Martin
Publicado 2021

P2A-Fluorophore Tagging of BRAF Tightly Links Expression to Fluorescence In Vivo

por van Veen, J. Edward, Pringle, Daphne R., McMahon, Martin
Publicado 2016

The relationship between subjective socioeconomic status and health in adults with and without intellectual disability

por McMahon, Martin, Hatton, Chris, Hardy, Claire, Preston, Nancy J.
Publicado 2022

Diminished WNT → β-catenin → c-MYC signaling is a barrier for malignant progression of BRAF(V600E)-induced lung tumors

por Juan, Joseph, Muraguchi, Teruyuki, Iezza, Gioia, Sears, Rosalie C., McMahon, Martin
Publicado 2014

Incidence and type of restrictive practice use in nursing homes in Ireland

por Dunbar, Paul, McMahon, Martin, Durkan, Ciara, Walsh, Kieran A., Keyes, Laura M.
Publicado 2022

Mortality in residential care facilities for people with disability: a descriptive cross-sectional analysis of statutory notifications in Ireland

por McMahon, Martin J, O'Connor, Aisling M, Dunbar, Paul, Delany, Anna, Behan, Laura, Grogan, Carol, Keyes, Laura M
Publicado 2023

Mutationally-activated PI3’-kinase-α promotes de-differentiation of lung tumors initiated by the BRAF(V600E) oncoprotein kinase

por van Veen, J Edward, Scherzer, Michael, Boshuizen, Julia, Chu, Mollee, Liu, Annie, Landman, Allison, Green, Shon, Trejo, Christy, McMahon, Martin
Publicado 2019

MYC-mediated resistance to trametinib and HCQ in PDAC is overcome by CDK4/6 and lysosomal inhibition

por Silvis, Mark R., Silva, Dilru, Rohweder, Riley, Schuman, Sophia, Gudipaty, Swapna, Truong, Amanda, Yap, Jeffrey, Affolter, Kajsa, McMahon, Martin, Kinsey, Conan
Publicado 2023

A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells

por Tomlinson, Michael G, Woods, Douglas B, McMahon, Martin, Wahl, Matthew I, Witte, Owen N, Kurosaki, Tomohiro, Bolen, Joseph B, Johnston, James A
Publicado 2001

PTEN phosphatase inhibits metastasis by negatively regulating the Entpd5/IGF1R pathway through ATF6

por Yu, Yanlin, Dai, Meng, Huang, Liping, Chen, Weiping, Yu, Ellen, Mendoza, Arnulfo, Michael, Helen, Khanna, Chand, Bosenberg, Marcus, McMahon, Martin, Merlino, Glenn
Publicado 2023

BRaf(V600E) cooperates with Pten silencing to elicit metastatic melanoma

por Dankort, David, Curley, David P., Cartlidge, Robert A., Nelson, Betsy, Karnezis, Anthony N., Damsky, William E., You, Mingjian J., DePinho, Ronald A., McMahon, Martin, Bosenberg, Marcus
Publicado 2009

Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAF(V600E) targeted inhibition in a novel syngeneic murine glioma model

por Grossauer, Stefan, Koeck, Katharina, Murphy, Nicole E., Meyers, Ian D., Daynac, Mathieu, Truffaux, Nathalene, Truong, Albert Y., Nicolaides, Theodore P., McMahon, Martin, Berger, Mitchel S., Phillips, Joanna J., James, David C., Petritsch, Claudia K.
Publicado 2016

BRAF(V600E) cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis

por Sakamoto, Naoya, Feng, Ying, Stolfi, Carmine, Kurosu, Yuki, Green, Maranne, Lin, Jeffry, Green, Megan E, Sentani, Kazuhiro, Yasui, Wataru, McMahon, Martin, Hardiman, Karin M, Spence, Jason R, Horita, Nobukatsu, Greenson, Joel K, Kuick, Rork, Cho, Kathleen R, Fearon, Eric R
Publicado 2017

A UV-independent pathway to melanoma carcinogenesis in the redhair-fairskin background

por Mitra, Devarati, Luo, Xi, Morgan, Ann, Wang, Jin, Hoang, Mai P., Lo, Jennifer, Guerrero, Candace R., Lennerz, Jochen K., Mihm, Martin C., Wargo, Jennifer A., Robinson, Kathleen C., Devi, Suprabha P., Vanover, Jillian C., D’Orazio, John A., McMahon, Martin, Bosenberg, Marcus W., Haigis, Kevin M., Haber, Daniel A., Wang, Yinsheng, Fisher, David E.
Publicado 2012

Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAF(V600E)-Driven Lung Tumorigenesis

por Vaishnavi, Aria, Juan, Joseph, Jacob, Maebh, Stehn, Christopher, Gardner, Eric E., Scherzer, Michael T., Schuman, Sophia, Van Veen, J. Edward, Murphy, Brandon, Hackett, Christopher S., Dupuy, Adam J., Chmura, Steven A., van der Weyden, Louise, Newberg, Justin Y., Liu, Annie, Mann, Karen, Rust, Alistair G., Weiss, William A., Kinsey, Conan G., Adams, David J., Grossmann, Allie, Mann, Michael B., McMahon, Martin
Publicado 2022

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers

por Kinsey, Conan G., Camolotto, Soledad A., Boespflug, Amelie M., Gullien, Katrin P., Foth, Mona, Truong, Amanda, Schuman, Sophia S., Shea, Jill E., Seipp, Michael T., Yap, Jeffrey T., Burrell, Lance D., Lum, David H., Whisenant, Jonathan R., Gilcrease, G. Weldon, Cavalieri, Courtney C., Rehbein, Kaitrin M., Cutler, Stephanie L., Affolter, Kajsa E., Welm, Alana L., Welm, Bryan E., Scaife, Courtney L., Snyder, Eric L., McMahon, Martin
Publicado 2019

Neurological manifestations of SARS-CoV-2 infection in hospitalised children and adolescents in the UK: a prospective national cohort study

por Ray, Stephen T J, Abdel-Mannan, Omar, Sa, Mario, Fuller, Charlotte, Wood, Greta K, Pysden, Karen, Yoong, Michael, McCullagh, Helen, Scott, David, McMahon, Martin, Thomas, Naomi, Taylor, Micheal, Illingworth, Marjorie, McCrea, Nadine, Davies, Victoria, Whitehouse, William, Zuberi, Sameer, Guthrie, Keira, Wassmer, Evangeline, Shah, Nikit, Baker, Mark R, Tiwary, Sangeeta, Tan, Hui Jeen, Varma, Uma, Ram, Dipak, Avula, Shivaram, Enright, Noelle, Hassell, Jane, Ross Russell, Amy L, Kumar, Ram, Mulholland, Rachel E, Pett, Sarah, Galea, Ian, Thomas, Rhys H, Benjamin, Laura A, Lim, Ming, Hacohen, Yael, Solomon, Tom, Griffiths, Michael J, Michael, Benedict D, Kneen, Rachel
Publicado 2021