Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-­A alleles in susceptibility to multiple sclerosis

por McMahon, Róisín M., Friis, Lone, Siebold, Christian, Friese, Manuel A., Fugger, Lars, Jones, E. Yvonne
Publicado 2011

An extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the HLA-DRB1 gene

por Ramagopalan, Sreeram V, McMahon, Roisin, Dyment, David A, Sadovnick, A Dessa, Ebers, George C, Wittkowski, Knut M
Publicado 2009

Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA

por Duprez, Wilko, Bachu, Prabhakar, Stoermer, Martin J., Tay, Stephanie, McMahon, Róisín M., Fairlie, David P., Martin, Jennifer L.
Publicado 2015

Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility

por McMahon, Roisin M., Coinçon, Mathieu, Tay, Stephanie, Heras, Begoña, Morton, Craig J., Scanlon, Martin J., Martin, Jennifer L.
Publicado 2015

Oxidoreductase disulfide bond proteins DsbA and DsbB form an active redox pair in Chlamydia trachomatis, a bacterium with disulfide dependent infection and development

por Christensen, Signe, Halili, Maria A., Strange, Natalie, Petit, Guillaume A., Huston, Wilhelmina M., Martin, Jennifer L., McMahon, Róisín M.
Publicado 2019

Structural and Biochemical Characterization of Chlamydia trachomatis DsbA Reveals a Cysteine-Rich and Weakly Oxidising Oxidoreductase

por Christensen, Signe, Grøftehauge, Morten K., Byriel, Karl, Huston, Wilhelmina M., Furlong, Emily, Heras, Begoña, Martin, Jennifer L., McMahon, Róisín M.
Publicado 2016

Virulence of the Melioidosis Pathogen Burkholderia pseudomallei Requires the Oxidoreductase Membrane Protein DsbB

por McMahon, Róisín M., Ireland, Philip M., Sarovich, Derek S., Petit, Guillaume, Jenkins, Christopher H., Sarkar-Tyson, Mitali, Currie, Bart J., Martin, Jennifer L.
Publicado 2018

Crystal structure and site-directed mutagenesis of circular bacteriocin plantacyclin B21AG reveals cationic and aromatic residues important for antimicrobial activity

por Gor, Mian-Chee, Vezina, Ben, McMahon, Róisín M., King, Gordon J., Panjikar, Santosh, Rehm, Bernd H. A., Martin, Jennifer L., Smith, Andrew T.
Publicado 2020

Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA

por Petit, Guillaume A., Mohanty, Biswaranjan, McMahon, Róisín M., Nebl, Stefan, Hilko, David H., Wilde, Karyn L., Scanlon, Martin J., Martin, Jennifer L., Halili, Maria A.
Publicado 2022

Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1

por Mohanty, Biswaranjan, Rimmer, Kieran, McMahon, Róisín M., Headey, Stephen J., Vazirani, Mansha, Shouldice, Stephen R., Coinçon, Mathieu, Tay, Stephanie, Morton, Craig J., Simpson, Jamie S., Martin, Jennifer L., Scanlon, Martin J.
Publicado 2017

Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials

por Wang, Geqing, Mohanty, Biswaranjan, Williams, Martin L., Doak, Bradley C., Dhouib, Rabeb, Totsika, Makrina, McMahon, Róisín M., Sharma, Gaurav, Zheng, Dan, Bentley, Matthew R., Ka‐Yan Chin, Yanni, Horne, James, Chalmers, David K., Heras, Begoña, Scanlon, Martin J.
Publicado 2022