An old probe sheds new light on BK channel pore structure

por McManus, Owen B., Rothberg, Brad S.
Publicado 2014

Inhale, exhale: Probing the inside-out mechanism of nicotine addiction using novel fluorescent sensors

por McManus, Owen B., Werley, Christopher A., Dempsey, Graham T.
Publicado 2019

Mechanism of Maxi-K Channel Activation by Dehydrosoyasaponin-I

por Giangiacomo, Kathleen M., Kamassah, Augustus, Harris, Guy, McManus, Owen B.
Publicado 1998

Ion Channels as Drug Targets: The Next GPCRs

por Kaczorowski, Gregory J., McManus, Owen B., Priest, Birgit T., Garcia, Maria L.
Publicado 2008

Oxidative Regulation of Large Conductance Calcium-Activated Potassium Channels

por Tang, Xiang D., Daggett, Heather, Hanner, Markus, Garcia, Maria L., McManus, Owen B., Brot, Nathan, Weissbach, Herbert, Heinemann, Stefan H., Hoshi, Toshinori
Publicado 2001

Identification and Characterization of ML352: A Novel, Noncompetitive Inhibitor of the Presynaptic Choline Transporter

por Ennis, Elizabeth A., Wright, Jane, Retzlaff, Cassandra L., McManus, Owen B., Lin, Zhinong, Huang, Xiaofang, Wu, Meng, Li, Min, Daniels, J. Scott, Lindsley, Craig W., Hopkins, Corey R., Blakely, Randy D.
Publicado 2015

Highly Parallelized, Multicolor Optogenetic Recordings of Cellular Activity for Therapeutic Discovery Applications in Ion Channels and Disease-Associated Excitable Cells

por Borja, Gabriel B., Zhang, Hongkang, Harwood, Benjamin N., Jacques, Jane, Grooms, Jennifer, Chantre, Romina O., Zhang, Dawei, Barnett, Adam, Werley, Christopher A., Lu, Yang, Nagle, Steven F., McManus, Owen B., Dempsey, Graham T.
Publicado 2022

Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls

por Simkin, Dina, Papakis, Vasileios, Bustos, Bernabe I., Ambrosi, Christina M., Ryan, Steven J., Baru, Valeriya, Williams, Luis A., Dempsey, Graham T., McManus, Owen B., Landers, John E., Lubbe, Steven J., George, Alfred L., Kiskinis, Evangelos
Publicado 2022

Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery

por Coussens, Nathan P., Sittampalam, G. Sitta, Guha, Rajarshi, Brimacombe, Kyle, Grossman, Abigail, Chung, Thomas D. Y., Weidner, Jeffrey R., Riss, Terry, Trask, O. Joseph, Auld, Douglas, Dahlin, Jayme L., Devanaryan, Viswanath, Foley, Timothy L., McGee, James, Kahl, Steven D., Kales, Stephen C., Arkin, Michelle, Baell, Jonathan, Bejcek, Bruce, Gal‐Edd, Neely, Glicksman, Marcie, Haas, Joseph V., Iversen, Philip W., Hoeppner, Marilu, Lathrop, Stacy, Sayers, Eric, Liu, Hanguan, Trawick, Bart, McVey, Julie, Lemmon, Vance P., Li, Zhuyin, McManus, Owen, Minor, Lisa, Napper, Andrew, Wildey, Mary Jo, Pacifici, Robert, Chin, William W., Xia, Menghang, Xu, Xin, Lal‐Nag, Madhu, Hall, Matthew D., Michael, Sam, Inglese, James, Simeonov, Anton, Austin, Christopher P.
Publicado 2018