From model system to clinical medicine: pathophysiologic links of common proteinopathies

por McMillan, Pamela J, Leverenz, James B
Publicado 2010

Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy

por Liachko, Nicole F., Saxton, Aleen D., McMillan, Pamela J., Strovas, Timothy J., Keene, C. Dirk, Bird, Thomas D., Kraemer, Brian C.
Publicado 2019

Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration

por Taylor, Laura M., McMillan, Pamela J., Liachko, Nicole F., Strovas, Timothy J., Ghetti, Bernardino, Bird, Thomas D., Keene, C. Dirk, Kraemer, Brian C.
Publicado 2018

Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes.

por Kow, Rebecca L., Strovas, Timothy J., McMillan, Pamela J., Jacobi, Ashley M., Behlke, Mark A., Saxton, Aleen D., Latimer, Caitlin S., Keene, C. Dirk, Kraemer, Brian C.
Publicado 2020

Pathological tau drives ectopic nuclear speckle scaffold protein SRRM2 accumulation in neuron cytoplasm in Alzheimer’s disease

por McMillan, Pamela J., Strovas, Timothy J., Baum, Misa, Mitchell, Brooke K., Eck, Randall J., Hendricks, Nzinga, Wheeler, Jeanna M., Latimer, Caitlin S., Keene, C. Dirk, Kraemer, Brian C.
Publicado 2021

Molecular Hydrogen in Drinking Water Protects against Neurodegenerative Changes Induced by Traumatic Brain Injury

por Dohi, Kenji, Kraemer, Brian C., Erickson, Michelle A., McMillan, Pamela J., Kovac, Andrej, Flachbartova, Zuzana, Hansen, Kim M., Shah, Gul N., Sheibani, Nader, Salameh, Therese, Banks, William A.
Publicado 2014

The Tau Tubulin Kinases TTBK1/2 Promote Accumulation of Pathological TDP-43

por Liachko, Nicole F., McMillan, Pamela J., Strovas, Timothy J., Loomis, Elaine, Greenup, Lynne, Murrell, Jill R., Ghetti, Bernardino, Raskind, Murray A., Montine, Thomas J., Bird, Thomas D., Leverenz, James B., Kraemer, Brian C.
Publicado 2014

High copy wildtype human 1N4R tau expression promotes early pathological tauopathy accompanied by cognitive deficits without progressive neurofibrillary degeneration

por Wheeler, Jeanna M., McMillan, Pamela J., Hawk, Michele, Iba, Michiyo, Robinson, Linda, Xu, George J., Dombroski, Beth A., Jeong, Doori, Dichter, Marc A., Juul, Halvor, Loomis, Elaine, Raskind, Murray, Leverenz, James B., Trojanowski, John Q., Lee, Virginia M.Y., Schellenberg, Gerard D., Kraemer, Brian C.
Publicado 2015