A Streamlined, Automated Protocol for the Production of Milligram Quantities of Untagged Recombinant Rat Lactate Dehydrogenase A Using ÄKTAxpress(TM)

por Nowicki, Matthew W., Blackburn, Elizabeth A., McNae, Iain W., Wear, Martin A.
Publicado 2015

Thermo‐kinetic analysis space expansion for cyclophilin‐ligand interactions – identification of a new nonpeptide inhibitor using Biacore™ T200

por Wear, Martin A., Nowicki, Matthew W., Blackburn, Elizabeth A., McNae, Iain W., Walkinshaw, Malcolm D.
Publicado 2017

The kinetic characteristics of human and trypanosomatid phosphofructokinases for the reverse reaction

por Fernandes, Peter M., Kinkead, James, McNae, Iain W., Bringaud, Frédéric, Michels, Paul A.M., Walkinshaw, Malcolm D.
Publicado 2019

Structures of pyruvate kinases display evolutionarily divergent allosteric strategies

por Morgan, Hugh P., Zhong, Wenhe, McNae, Iain W., Michels, Paul A. M., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D.
Publicado 2014

Structures of Leishmania Fructose-1,6-Bisphosphatase Reveal Species-Specific Differences in the Mechanism of Allosteric Inhibition

por Yuan, Meng, Vásquez-Valdivieso, Montserrat G., McNae, Iain W., Michels, Paul A.M., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D.
Publicado 2017

Kinetic and structural studies of Trypanosoma and Leishmania phosphofructokinases show evolutionary divergence and identify AMP as a switch regulating glycolysis versus gluconeogen...

por Fernandes, Peter M., Kinkead, James, McNae, Iain W., Vásquez‐Valdivieso, Monserrat, Wear, Martin A., Michels, Paul A. M., Walkinshaw, Malcolm D.
Publicado 2020

An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor

por Yuan, Meng, McNae, Iain W., Chen, Yiyuan, Blackburn, Elizabeth A., Wear, Martin A., Michels, Paul A.M., Fothergill-Gilmore, Linda A., Hupp, Ted, Walkinshaw, Malcolm D.
Publicado 2018

Redox regulation of pyruvate kinase M2 by cysteine oxidation and S-nitrosation

por Mitchell, Alice Rose, Yuan, Meng, Morgan, Hugh P., McNae, Iain W., Blackburn, Elizabeth A., Le Bihan, Thierry, Homem, Rafael A., Yu, Manda, Loake, Gary J., Michels, Paul A., Wear, Martin A., Walkinshaw, Malcolm D.
Publicado 2018

Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice

por McNae, Iain W., Kinkead, James, Malik, Divya, Yen, Li-Hsuan, Walker, Martin K., Swain, Chris, Webster, Scott P., Gray, Nick, Fernandes, Peter M., Myburgh, Elmarie, Blackburn, Elizabeth A., Ritchie, Ryan, Austin, Carol, Wear, Martin A., Highton, Adrian J., Keats, Andrew J., Vong, Antonio, Dornan, Jacqueline, Mottram, Jeremy C., Michels, Paul A. M., Pettit, Simon, Walkinshaw, Malcolm D.
Publicado 2021