Backbone-independent NMR resonance assignments of methyl probes in large proteins

por Nerli, Santrupti, De Paula, Viviane S., McShan, Andrew C., Sgourakis, Nikolaos G.
Publicado 2021

TAPBPR promotes antigen loading on MHC-I molecules using a peptide trap

por McShan, Andrew C., Devlin, Christine A., Morozov, Giora I., Overall, Sarah A., Moschidi, Danai, Akella, Neha, Procko, Erik, Sgourakis, Nikolaos G.
Publicado 2021

The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling

por Natarajan, Kannan, Jiang, Jiansheng, May, Nathan A., Mage, Michael G., Boyd, Lisa F., McShan, Andrew C., Sgourakis, Nikolaos G., Bax, Ad, Margulies, David H.
Publicado 2018

Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection

por McShan, Andrew C., Devlin, Christine A., Overall, Sarah A., Park, Jihye, Toor, Jugmohit S., Moschidi, Danai, Flores-Solis, David, Choi, Hannah, Tripathi, Sarvind, Procko, Erik, Sgourakis, Nikolaos G.
Publicado 2019

De novo design of a non-local β-sheet protein with high stability and accuracy

por Marcos, Enrique, Chidyausiku, Tamuka M., McShan, Andrew C., Evangelidis, Thomas, Nerli, Santrupti, Carter, Lauren, Nivón, Lucas G., Davis, Audrey, Oberdorfer, Gustav, Tripsianes, Konstantinos, Sgourakis, Nikolaos G., Baker, David
Publicado 2018

An order-to-disorder structural switch activates the FoxM1 transcription factor

por Marceau, Aimee H, Brison, Caileen M, Nerli, Santrupti, Arsenault, Heather E, McShan, Andrew C, Chen, Eefei, Lee, Hsiau-Wei, Benanti, Jennifer A, Sgourakis, Nikolaos G, Rubin, Seth M
Publicado 2019

Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle

por McShan, Andrew C., Natarajan, Kannan, Kumirov, Vlad K., Flores-Solis, David, Jiang, Jiansheng, Badstübner, Mareike, Toor, Jugmohit S., Bagshaw, Clive R., Kovrigin, Evgenii L., Margulies, David H., Sgourakis, Nikolaos G.
Publicado 2018

De novo design of a homo-trimeric amantadine-binding protein

por Park, Jooyoung, Selvaraj, Brinda, McShan, Andrew C, Boyken, Scott E, Wei, Kathy Y, Oberdorfer, Gustav, DeGrado, William, Sgourakis, Nikolaos G, Cuneo, Matthew J, Myles, Dean AA, Baker, David
Publicado 2019

Computational design of closely related proteins that adopt two well-defined but structurally divergent folds

por Wei, Kathy Y., Moschidi, Danai, Bick, Matthew J., Nerli, Santrupti, McShan, Andrew C., Carter, Lauren P., Huang, Po-Ssu, Fletcher, Daniel A., Sgourakis, Nikolaos G., Boyken, Scott E., Baker, David
Publicado 2020

An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role

por Natarajan, Kannan, McShan, Andrew C., Jiang, Jiansheng, Kumirov, Vlad K, Wang, Rui, Zhao, Huaying, Schuck, Peter, Tilahun, Mulualem E., Boyd, Lisa F., Ying, Jinfa, Bax, Ad, Margulies, David H., Sgourakis, Nikolaos G.
Publicado 2017

A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations

por Toor, Jugmohit S., Rao, Arjun A., McShan, Andrew C., Yarmarkovich, Mark, Nerli, Santrupti, Yamaguchi, Karissa, Madejska, Ada A., Nguyen, Son, Tripathi, Sarvind, Maris, John M., Salama, Sofie R., Haussler, David, Sgourakis, Nikolaos G.
Publicado 2018