Rosetta Energy Analysis of AlphaFold2 models: Point Mutations and Conformational Ensembles

por Stein, Richard A., Mchaourab, Hassane S.
Publicado 2023

SPEACH_AF: Sampling protein ensembles and conformational heterogeneity with Alphafold2

por Stein, Richard A., Mchaourab, Hassane S.
Publicado 2022

Protein functional dynamics from the rigorous global analysis of DEER data: Conditions, components, and conformations

por Hustedt, Eric J., Stein, Richard A., Mchaourab, Hassane S.
Publicado 2021

Interplay between Nrf2 and αB-crystallin in the lens and heart of zebrafish under proteostatic stress

por Park, Jinhee, MacGavin, Samantha, Niederbrach, Laurie, Mchaourab, Hassane S.
Publicado 2023

Transgenic zebrafish models reveal distinct molecular mechanisms for cataract-linked αA-crystallin mutants

por Wu, Shu-Yu, Zou, Ping, Mishra, Sanjay, Mchaourab, Hassane S.
Publicado 2018

Sampling alternative conformational states of transporters and receptors with AlphaFold2

por del Alamo, Diego, Sala, Davide, Mchaourab, Hassane S, Meiler, Jens
Publicado 2022

Generation and characterization of a zebrafish knockout model of abcb4, a homolog of the human multidrug efflux transporter P-glycoprotein

por Park, Jinhee, Kim, Hyosung, alabdalla, Leen, Mishra, Smriti, Mchaourab, Hassane
Publicado 2023

Approximating conformational Boltzmann distributions with AlphaFold2 predictions

por Brown, Benjamin P., Stein, Richard A., Meiler, Jens, Mchaourab, Hassane
Publicado 2023

Generation and characterization of a zebrafish knockout model of abcb4, a homolog of the human multidrug efflux transporter P-glycoprotein

por Park, Jinhee, Kim, Hyosung, Alabdalla, Leen, Mishra, Smriti, Mchaourab, Hassane
Publicado 2023

Methodology for rigorous modeling of protein conformational changes by Rosetta using DEER distance restraints

por del Alamo, Diego, Jagessar, Kevin L., Meiler, Jens, Mchaourab, Hassane S.
Publicado 2021

On the Origin of Large Flexibility of P-glycoprotein in the Inward-facing State

por Wen, Po-Chao, Verhalen, Brandy, Wilkens, Stephan, Mchaourab, Hassane S., Tajkhorshid, Emad
Publicado 2013

Movement of the RecG Motor Domain upon DNA Binding Is Required for Efficient Fork Reversal

por Warren, Garrett M., Stein, Richard A., Mchaourab, Hassane S., Eichman, Brandt F.
Publicado 2018

Conformational Motion of the ABC Transporter MsbA Induced by ATP Hydrolysis

por Borbat, Peter P, Surendhran, Kavitha, Bortolus, Marco, Zou, Ping, Freed, Jack H, Mchaourab, Hassane S
Publicado 2007

Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter

por Mishra, Smriti, Verhalen, Brandy, Stein, Richard A, Wen, Po-Chao, Tajkhorshid, Emad, Mchaourab, Hassane S
Publicado 2014

Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter

por Tang, Qingyu, Sinclair, Matt, Hasdemir, Hale S., Stein, Richard A., Karakas, Erkan, Tajkhorshid, Emad, Mchaourab, Hassane S.
Publicado 2023

RosettaEPR: Rotamer Library for Spin Label Structure and Dynamics

por Alexander, Nathan S., Stein, Richard A., Koteiche, Hanane A., Kaufmann, Kristian W., Mchaourab, Hassane S., Meiler, Jens
Publicado 2013

Biophysical and functional properties of purified glucose-6-phosphatase catalytic subunit 1

por Claxton, Derek P., Overway, Emily M., Oeser, James K., O'Brien, Richard M., Mchaourab, Hassane S.
Publicado 2021

Integrated AlphaFold2 and DEER investigation of the conformational dynamics of a pH-dependent APC antiporter

por del Alamo, Diego, DeSousa, Lillian, Nair, Rahul M., Rahman, Suhaila, Meiler, Jens, Mchaourab, Hassane S.
Publicado 2022

Conformational dynamics of ligand-dependent alternating access in LeuT

por Kazmier, Kelli, Sharma, Shruti, Quick, Matthias, Islam, Shahidul M., Roux, Benoit, Weinstein, Harel, Javitch, Jonathan A., Mchaourab, Hassane S.
Publicado 2014

Energy Transduction and Alternating Access of the Mammalian ABC Transporter P-glycoprotein

por Verhalen, Brandy, Dastvan, Reza, Thangapandian, Sundarapandian, Peskova, Yelena, Koteiche, Hanane A., Nakamoto, Robert K., Tajkhorshid, Emad, Mchaourab, Hassane S.
Publicado 2017