Female adipose tissue-specific Bscl2 knockout mice develop only moderate metabolic dysfunction when housed at thermoneutrality and fed a high-fat diet

por Mcilroy, George D., Mitchell, Sharon E., Han, Weiping, Delibegović, Mirela, Rochford, Justin J.
Publicado 2018

Ablation of Bscl2/seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy

por Mcilroy, George D., Mitchell, Sharon E., Han, Weiping, Delibegović, Mirela, Rochford, Justin J.
Publicado 2020

Gene therapy restores adipose tissue and metabolic health in a pre-clinical mouse model of lipodystrophy

por Sommer, Nadine, Roumane, Ahlima, Han, Weiping, Delibegović, Mirela, Rochford, Justin J., Mcilroy, George D.
Publicado 2022

Bscl2 Deficiency Does Not Directly Impair the Innate Immune Response in a Murine Model of Generalized Lipodystrophy

por Roumane, Ahlima, Mcilroy, George D., Balci, Arda, Han, Weiping, Delibegović, Mirela, Baldassarre, Massimiliano, Newsholme, Philip, Rochford, Justin J.
Publicado 2021

Fenretinide Treatment Prevents Diet-Induced Obesity in Association With Major Alterations in Retinoid Homeostatic Gene Expression in Adipose, Liver, and Hypothalamus

por Mcilroy, George D., Delibegovic, Mirela, Owen, Carl, Stoney, Patrick N., Shearer, Kirsty D., McCaffery, Peter J., Mody, Nimesh
Publicado 2013

Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation

por Sim, M. F. Michelle, Persiani, Elisa, Talukder, Md. Mesbah Uddin, Mcilroy, George D., Roumane, Ahlima, Edwardson, J. Michael, Rochford, Justin J.
Publicado 2020

Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice

por Morrice, Nicola, Mcilroy, George D., Tammireddy, Seshu R., Reekie, Jennifer, Shearer, Kirsty D., Doherty, Mary K., Delibegović, Mirela, Whitfield, Phillip D., Mody, Nimesh
Publicado 2017

Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stres...

por Mcilroy, George D., Tammireddy, Seshu R., Maskrey, Benjamin H., Grant, Louise, Doherty, Mary K., Watson, David G., Delibegović, Mirela, Whitfield, Phillip D., Mody, Nimesh
Publicado 2016

Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease

por Mcilroy, George D., Suchacki, Karla, Roelofs, Anke J., Yang, Wulin, Fu, Yanyun, Bai, Bo, Wallace, Robert J., De Bari, Cosimo, Cawthorn, William P., Han, Weiping, Delibegović, Mirela, Rochford, Justin J.
Publicado 2018

Adipocyte-Specific Protein Tyrosine Phosphatase 1B Deletion Increases Lipogenesis, Adipocyte Cell Size and Is a Minor Regulator of Glucose Homeostasis

por Owen, Carl, Czopek, Alicja, Agouni, Abdelali, Grant, Louise, Judson, Robert, Lees, Emma K., Mcilroy, George D., Göransson, Olga, Welch, Andy, Bence, Kendra K., Kahn, Barbara B., Neel, Benjamin G., Mody, Nimesh, Delibegović, Mirela
Publicado 2012

Correction: Adipocyte-Specific Protein Tyrosine Phosphatase 1B Deletion Increases Lipogenesis, Adipocyte Cell Size and Is a Minor Regulator of Glucose Homeostasis

por Owen, Carl, Czopek, Alicja, Agouni, Abdelali, Grant, Louise, Judson, Robert, Lees, Emma K., Mcilroy, George D., Göransson, Olga, Welch, Andy, Bence, Kendra K., Kahn, Barbara B., Neel, Benjamin G., Mody, Nimesh, Delibegović, Mirela
Publicado 2012