Threshold for Pre-existing Antibody Levels Limiting Transduction Efficiency of Systemic rAAV9 Gene Delivery: Relevance for Translation

por Meadows, Aaron S., Pineda, Ricardo J., Goodchild, Laurie, Bobo, Tierra A., Fu, Haiyan
Publicado 2019

Effective Depletion of Pre-existing Anti-AAV Antibodies Requires Broad Immune Targeting

por Velazquez, Victoria M., Meadows, Aaron S., Pineda, Ricardo J., Camboni, Marybeth, McCarty, Douglas M., Fu, Haiyan
Publicado 2017

Targeting Root Cause by Systemic scAAV9-hIDS Gene Delivery: Functional Correction and Reversal of Severe MPS II in Mice

por Fu, Haiyan, Zaraspe, Kim, Murakami, Naoko, Meadows, Aaron S., Pineda, Ricardo J., McCarty, Douglas M., Muenzer, Joseph
Publicado 2018

Amyloidosis, Synucleinopathy, and Prion Encephalopathy in a Neuropathic Lysosomal Storage Disease: The CNS-Biomarker Potential of Peripheral Blood

por Naughton, Bartholomew J., Duncan, F. Jason, Murrey, Darren, Ware, Tierra, Meadows, Aaron, McCarty, Douglas M., Fu, Haiyan
Publicado 2013

Functional correction of neurological and somatic disorders at later stages of disease in MPS IIIA mice by systemic scAAV9-hSGSH gene delivery

por Fu, Haiyan, Cataldi, Marcela P, Ware, Tierra A, Zaraspe, Kimberly, Meadows, Aaron S, Murrey, Darren A, McCarty, Douglas M
Publicado 2016