The W101C KCNJ5 Mutation Induces Slower Pacing by Constitutively Active GIRK Channels in hiPSC-Derived Cardiomyocytes

por Kayser, Anne, Dittmann, Sven, Šarić, Tomo, Mearini, Giulia, Verkerk, Arie O., Schulze-Bahr, Eric
Publicado 2023

Inhibition of Poly(ADP-ribose)polymerase impairs Epstein Barr Virus lytic cycle progression

por Mattiussi, Stefania, Tempera, Italo, Matusali, Giulia, Mearini, Giulia, Lenti, Luisa, Fratarcangeli, Silvia, Mosca, Luciana, D'Erme, Maria, Mattia, Elena
Publicado 2007

Analysis of Contractile Function of Permeabilized Human Hypertrophic Cardiomyopathy Multicellular Heart Tissue

por Kresin, Nico, Stücker, Sabrina, Krämer, Elisabeth, Flenner, Frederik, Mearini, Giulia, Münch, Julia, Patten, Monica, Redwood, Charles, Carrier, Lucie, Friedrich, Felix W.
Publicado 2019

Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes

por Kloth, Benjamin, Mearini, Giulia, Weinberger, Florian, Stenzig, Justus, Geertz, Birgit, Starbatty, Jutta, Lindner, Diana, Schumacher, Udo, Reichenspurner, Hermann, Eschenhagen, Thomas, Hirt, Marc N.
Publicado 2022

BSE-associated Prion-Amyloid Cardiomyopathy in Primates

por Krasemann, Susanne, Mearini, Giulia, Krämer, Elisabeth, Wagenführ, Katja, Schulz-Schaeffer, Walter, Neumann, Melanie, Bodemer, Walter, Kaup, Franz-Josef, Beekes, Michael, Carrier, Lucie, Aguzzi, Adriano, Glatzel, Markus
Publicado 2013

Evaluation of MYBPC3 trans-Splicing and Gene Replacement as Therapeutic Options in Human iPSC-Derived Cardiomyocytes

por Prondzynski, Maksymilian, Krämer, Elisabeth, Laufer, Sandra D., Shibamiya, Aya, Pless, Ole, Flenner, Frederik, Müller, Oliver J., Münch, Julia, Redwood, Charles, Hansen, Arne, Patten, Monica, Eschenhagen, Thomas, Mearini, Giulia, Carrier, Lucie
Publicado 2017

Repair of Mybpc3 mRNA by 5′-trans-splicing in a Mouse Model of Hypertrophic Cardiomyopathy

por Mearini, Giulia, Stimpel, Doreen, Krämer, Elisabeth, Geertz, Birgit, Braren, Ingke, Gedicke-Hornung, Christina, Précigout, Guillaume, Müller, Oliver J, Katus, Hugo A, Eschenhagen, Thomas, Voit, Thomas, Garcia, Luis, Lorain, Stéphanie, Carrier, Lucie
Publicado 2013

Phosphomimetic cardiac myosin-binding protein C partially rescues a cardiomyopathy phenotype in murine engineered heart tissue

por Dutsch, Alexander, Wijnker, Paul J. M., Schlossarek, Saskia, Friedrich, Felix W., Krämer, Elisabeth, Braren, Ingke, Hirt, Marc N., Brenière-Letuffe, David, Rhoden, Alexandra, Mannhardt, Ingra, Eschenhagen, Thomas, Carrier, Lucie, Mearini, Giulia
Publicado 2019

Rescue of cardiomyopathy through U7snRNA-mediated exon skipping in Mybpc3-targeted knock-in mice

por Gedicke-Hornung, Christina, Behrens-Gawlik, Verena, Reischmann, Silke, Geertz, Birgit, Stimpel, Doreen, Weinberger, Florian, Schlossarek, Saskia, Précigout, Guillaume, Braren, Ingke, Eschenhagen, Thomas, Mearini, Giulia, Lorain, Stéphanie, Voit, Thomas, Dreyfus, Patrick A, Garcia, Luis, Carrier, Lucie
Publicado 2013

Endothelin‐1 Induces Myofibrillar Disarray and Contractile Vector Variability in Hypertrophic Cardiomyopathy–Induced Pluripotent Stem Cell–Derived Cardiomyocytes

por Tanaka, Atsushi, Yuasa, Shinsuke, Mearini, Giulia, Egashira, Toru, Seki, Tomohisa, Kodaira, Masaki, Kusumoto, Dai, Kuroda, Yusuke, Okata, Shinichiro, Suzuki, Tomoyuki, Inohara, Taku, Arimura, Takuro, Makino, Shinji, Kimura, Kensuke, Kimura, Akinori, Furukawa, Tetsushi, Carrier, Lucie, Node, Koichi, Fukuda, Keiichi
Publicado 2014

ACTN2 Mutant Causes Proteopathy in Human iPSC-Derived Cardiomyocytes

por Zech, Antonia T. L., Prondzynski, Maksymilian, Singh, Sonia R., Pietsch, Niels, Orthey, Ellen, Alizoti, Erda, Busch, Josefine, Madsen, Alexandra, Behrens, Charlotta S., Meyer-Jens, Moritz, Mearini, Giulia, Lemoine, Marc D., Krämer, Elisabeth, Mosqueira, Diogo, Virdi, Sanamjeet, Indenbirken, Daniela, Depke, Maren, Salazar, Manuela Gesell, Völker, Uwe, Braren, Ingke, Pu, William T., Eschenhagen, Thomas, Hammer, Elke, Schlossarek, Saskia, Carrier, Lucie
Publicado 2022

Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

por Prondzynski, Maksymilian, Lemoine, Marc D, Zech, Antonia TL, Horváth, András, Di Mauro, Vittoria, Koivumäki, Jussi T, Kresin, Nico, Busch, Josefine, Krause, Tobias, Krämer, Elisabeth, Schlossarek, Saskia, Spohn, Michael, Friedrich, Felix W, Münch, Julia, Laufer, Sandra D, Redwood, Charles, Volk, Alexander E, Hansen, Arne, Mearini, Giulia, Catalucci, Daniele, Meyer, Christian, Christ, Torsten, Patten, Monica, Eschenhagen, Thomas, Carrier, Lucie
Publicado 2019