Uptake of genetic testing by the children of Lynch syndrome variant carriers across three generations

por Seppälä, Toni T, Pylvänäinen, Kirsi, Mecklin, Jukka-Pekka
Publicado 2017

Clinical characteristics of pancreatic and biliary tract cancers in Lynch syndrome: A retrospective analysis from the Finnish National Lynch Syndrome Research Registry

por Zalevskaja, Kristina, Mecklin, Jukka-Pekka, Seppälä, Toni T.
Publicado 2023

Endometrial cancer risk factors among Lynch syndrome women: a retrospective cohort study

por Staff, Synnöve, Aaltonen, Mari, Huhtala, Heini, Pylvänäinen, Kirsi, Mecklin, Jukka-Pekka, Mäenpää, Johanna
Publicado 2016

Descriptive study on subjective experience of genetic testing with respect to relationship, family planning and psychosocial wellbeing among women with lynch syndrome

por Kalamo, Mari, Mäenpää, Johanna, Seppälä, Toni, Mecklin, Jukka-Pekka, Pylvänäinen, Kirsi, Staff, Synnöve
Publicado 2021

Numbers of mutations to different types of colorectal cancer

por Calabrese, Peter, Mecklin, Jukka-Pekka, Järvinen, Heikki J, Aaltonen, Lauri A, Tavaré, Simon, Shibata, Darryl
Publicado 2005

DNA hypermethylation appears early and shows increased frequency with dysplasia in Lynch syndrome-associated colorectal adenomas and carcinomas

por Valo, Satu, Kaur, Sippy, Ristimäki, Ari, Renkonen-Sinisalo, Laura, Järvinen, Heikki, Mecklin, Jukka-Pekka, Nyström, Minna, Peltomäki, Päivi
Publicado 2015

Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas

por Porkka, Noora K., Olkinuora, Alisa, Kuopio, Teijo, Ahtiainen, Maarit, Eldfors, Samuli, Almusa, Henrikki, Mecklin, Jukka-Pekka, Peltomäki, Päivi
Publicado 2020

Molecular Basis of Mismatch Repair Protein Deficiency in Tumors from Lynch Suspected Cases with Negative Germline Test Results

por Olkinuora, Alisa, Gylling, Annette, Almusa, Henrikki, Eldfors, Samuli, Lepistö, Anna, Mecklin, Jukka-Pekka, Nieminen, Taina Tuulikki, Peltomäki, Päivi
Publicado 2020

Prognostic Value of Immune Environment Analysis in Small Bowel Adenocarcinomas with Verified Mutational Landscape and Predisposing Conditions

por Wirta, Erkki-Ville, Szeto, Säde, Hänninen, Ulrika, Ahtiainen, Maarit, Böhm, Jan, Mecklin, Jukka-Pekka, Aaltonen, Lauri A., Seppälä, Toni T.
Publicado 2020

Testing for Lynch Syndrome in Endometrial Carcinoma: From Universal to Age-Selective MLH1 Methylation Analysis

por Pasanen, Annukka, Loukovaara, Mikko, Kaikkonen, Elina, Olkinuora, Alisa, Pylvänäinen, Kirsi, Alhopuro, Pia, Peltomäki, Päivi, Mecklin, Jukka-Pekka, Bützow, Ralf
Publicado 2022

Body Weight, Physical Activity, and Risk of Cancer in Lynch Syndrome

por Sievänen, Tero, Törmäkangas, Timo, Laakkonen, Eija K., Mecklin, Jukka-Pekka, Pylvänäinen, Kirsi, Seppälä, Toni T., Peltomäki, Päivi, Sipilä, Sarianna, Sillanpää, Elina
Publicado 2021

Impact of Age and Comorbidity on Multimodal Management and Survival from Colorectal Cancer: A Population-Based Study

por Kellokumpu, Ilmo, Kairaluoma, Matti, Mecklin, Jukka-Pekka, Kellokumpu, Henrik, Väyrynen, Ville, Wirta, Erkki-Ville, Sihvo, Eero, Kuopio, Teijo, Seppälä, Toni T.
Publicado 2021

Stromal hyaluronan accumulation is associated with low immune response and poor prognosis in pancreatic cancer

por Tahkola, Kyösti, Ahtiainen, Maarit, Mecklin, Jukka-Pekka, Kellokumpu, Ilmo, Laukkarinen, Johanna, Tammi, Markku, Tammi, Raija, Väyrynen, Juha P., Böhm, Jan
Publicado 2021

Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci

por Niittymäki, Iina, Tuupanen, Sari, Li, Yilong, Järvinen, Heikki, Mecklin, Jukka-Pekka, Tomlinson, Ian PM, Houlston, Richard S, Karhu, Auli, Aaltonen, Lauri A
Publicado 2011

A Comparative Pan-Genome Perspective of Niche-Adaptable Cell-Surface Protein Phenotypes in Lactobacillus rhamnosus

por Kant, Ravi, Rintahaka, Johanna, Yu, Xia, Sigvart-Mattila, Pia, Paulin, Lars, Mecklin, Jukka-Pekka, Saarela, Maria, Palva, Airi, von Ossowski, Ingemar
Publicado 2014

Epigenetic analysis of sporadic and Lynch-associated ovarian cancers reveals histology-specific patterns of DNA methylation

por Niskakoski, Anni, Kaur, Sippy, Staff, Synnöve, Renkonen-Sinisalo, Laura, Lassus, Heini, Järvinen, Heikki J, Mecklin, Jukka-Pekka, Bützow, Ralf, Peltomäki, Päivi
Publicado 2015

The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking β-Catenin/TCF Regulated Transcription

por Abdel-Rahman, Wael M., Lotsari-Salomaa, Johanna E., Kaur, Sippy, Niskakoski, Anni, Knuutila, Sakari, Järvinen, Heikki, Mecklin, Jukka-Pekka, Peltomäki, Päivi
Publicado 2016

Prognostic impact of CD73 expression and its relationship to PD-L1 in patients with radically treated pancreatic cancer

por Tahkola, Kyösti, Ahtiainen, Maarit, Kellokumpu, Ilmo, Mecklin, Jukka-Pekka, Laukkarinen, Johanna, Laakkonen, Joni, Kenessey, Istvan, Jalkanen, Sirpa, Salmi, Marko, Böhm, Jan
Publicado 2020

Immune Contexture of MMR-Proficient Primary Colorectal Cancer and Matched Liver and Lung Metastases

por Ahtiainen, Maarit, Elomaa, Hanna, Väyrynen, Juha P., Wirta, Erkki-Ville, Kuopio, Teijo, Helminen, Olli, Seppälä, Toni T., Kellokumpu, Ilmo, Mecklin, Jukka-Pekka
Publicado 2021

Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis

por Mäki-Nevala, Satu, Ukwattage, Sanjeevi, Wirta, Erkki-Ville, Ahtiainen, Maarit, Ristimäki, Ari, Seppälä, Toni T., Lepistö, Anna, Mecklin, Jukka-Pekka, Peltomäki, Päivi
Publicado 2021