Editorial: Thrombosis meets inflammation

por Kolev, Krasimir, Medcalf, Robert L.
Publicado 2023

Editorial: Fibrinolysis in Immunity

por Kolev, Krasimir, Medcalf, Robert L.
Publicado 2020

Editorial: The Role of the Plasminogen Activating System in Neurobiology

por Medcalf, Robert L., Lawrence, Daniel A.
Publicado 2016

Fibrinolysis: A Primordial System Linked to the Immune Response

por Medcalf, Robert L., Keragala, Charithani B.
Publicado 2021

The Fibrinolytic System: Mysteries and Opportunities

por Medcalf, Robert L., Keragala, Charithani B.
Publicado 2021

Plasmin, Immunity, and Surgical Site Infection

por Hastings, Stuart, Myles, Paul S., Medcalf, Robert L.
Publicado 2021

The relationship between the prothrombin upstream sequence element and the G20210A polymorphism: the influence of a competitive environment for mRNA 3′-end formation

por Sachchithananthan, Mythily, Stasinopoulos, Stan J., Wilusz, Jeffrey, Medcalf, Robert L.
Publicado 2005

A novel ex vivo approach for measuring plasminogen activation upon established plasma clots

por Palazzolo, Jason S., Medcalf, Robert L., Hagemeyer, Christoph E., Niego, Be'eri
Publicado 2022

Tissue-type plasminogen activator induces conditioned receptive field plasticity in the mouse auditory cortex

por Smart, Caitlin, Mitchell, Anna, McCutcheon, Fiona, Medcalf, Robert L., Thiele, Alexander
Publicado 2023

Tranexamic acid for haemostasis and beyond: does dose matter?

por Lam, Tammy, Medcalf, Robert L., Cloud, Geoffrey C., Myles, Paul S., Keragala, Charithani B.
Publicado 2023

What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies

por Picetti, Roberto, Shakur-Still, Haleema, Medcalf, Robert L., Standing, Joseph F., Roberts, Ian
Publicado 2019

Species-Specific Regulation of t-PA and PAI-1 Gene Expression in Human and Rat Astrocytes

por Tjärnlund-Wolf, Anna, Hultman, Karin, Blomstrand, Fredrik, Nilsson, Michael, Medcalf, Robert L, Jern, Christina
Publicado 2014

LDL receptor blockade reduces mortality in a mouse model of ischaemic stroke without improving tissue-type plasminogen activator-induced brain haemorrhage: towards pre-clinical sim...

por Niego, Be’eri, Broughton, Brad R. S., Ho, Heidi, Sobey, Christopher G., Medcalf, Robert L.
Publicado 2017

t-PA Suppresses the Immune Response and Aggravates Neurological Deficit in a Murine Model of Ischemic Stroke

por Draxler, Dominik F., Lee, Felix, Ho, Heidi, Keragala, Charithani B., Medcalf, Robert L., Niego, Be'eri
Publicado 2019

Tissue-Type Plasminogen Activator and Tenecteplase-Mediated Increase in Blood Brain Barrier Permeability Involves Cell Intrinsic Complement

por Keragala, Charithani B., Woodruff, Trent M., Liu, Zikou, Niego, Be'eri, Ho, Heidi, McQuilten, Zoe, Medcalf, Robert L.
Publicado 2020

Selective inhibition of brain endothelial Rho-kinase-2 provides optimal protection of an in vitro blood-brain barrier from tissue-type plasminogen activator and plasmin

por Niego, Be’eri, Lee, Natasha, Larsson, Pia, De Silva, T. Michael, Au, Amanda E-Ling, McCutcheon, Fiona, Medcalf, Robert L.
Publicado 2017

Physicochemical properties that control protein aggregation also determine whether a protein is retained or released from necrotic cells

por Samson, Andre L., Ho, Bosco, Au, Amanda E., Schoenwaelder, Simone M., Smyth, Mark J., Bottomley, Stephen P., Kleifeld, Oded, Medcalf, Robert L.
Publicado 2016

Tranexamic acid in a mouse model of cerebral amyloid angiopathy: setting the stage for a novel stroke treatment approach

por Liu, Zikou, McCutcheon, Fiona M., Ho, Heidi, Chia, Joanne, Xiao, Yunxin, Tippett, Isabel, Keragala, Charithani B., Cloud, Geoffrey C., Medcalf, Robert L.
Publicado 2023

Role of Histone Acetylation in the Stimulatory Effect of Valproic Acid on Vascular Endothelial Tissue-Type Plasminogen Activator Expression

por Larsson, Pia, Ulfhammer, Erik, Magnusson, Mia, Bergh, Niklas, Lunke, Sebastian, El-Osta, Assam, Medcalf, Robert L., Svensson, Per-Arne, Karlsson, Lena, Jern, Sverker
Publicado 2012

Point-of-care diagnosis and monitoring of fibrinolysis resistance in the critically ill: results from a feasibility study

por Coupland, Lucy A., Rabbolini, David J., Schoenecker, Jonathan G., Crispin, Philip J., Miller, Jennene J., Ghent, Tony, Medcalf, Robert L., Aneman, Anders E.
Publicado 2023