BCL-2 family deregulation in colorectal cancer: potential for BH3 mimetics in therapy

por Ramesh, Prashanthi, Medema, Jan Paul
Publicado 2020

Intra-tumor heterogeneity from a cancer stem cell perspective

por Prasetyanti, Pramudita R., Medema, Jan Paul
Publicado 2017

Kinase-targeted therapy in subsets of colorectal cancer

por Gomez Barila, Patricia M., Medema, Jan Paul
Publicado 2023

Molecular identification and targeting of colorectal cancer stem cells

por Kemper, Kristel, Grandela, Catarina, Medema, Jan Paul
Publicado 2010

Endothelial cells induce cancer stem cell features in differentiated glioblastoma cells via bFGF

por Fessler, Evelyn, Borovski, Tijana, Medema, Jan Paul
Publicado 2015

Exploring and modelling colon cancer inter-tumour heterogeneity: opportunities and challenges

por Buikhuisen, Joyce Y., Torang, Arezo, Medema, Jan Paul
Publicado 2020

Betulin Is a Potent Anti-Tumor Agent that Is Enhanced by Cholesterol

por Mullauer, Franziska B., Kessler, Jan H., Medema, Jan Paul
Publicado 2009

BH3 Mimetic Sensitivity of Colorectal Cancer Cell Lines in Correlation with Molecular Features Identifies Predictors of Response

por Zhang, Le, Ramesh, Prashanthi, Steinmetz, Maxime, Medema, Jan Paul
Publicado 2021

Mouse Tissues Express Multiple Splice Variants of Prominin-1

por Kemper, Kristel, Tol, Marc J. P. M., Medema, Jan Paul
Publicado 2010

The Role of Cancer-Associated Fibroblasts in Cancer Invasion and Metastasis

por Asif, Paris Jabeen, Longobardi, Ciro, Hahne, Michael, Medema, Jan Paul
Publicado 2021

Targeting colorectal cancer stem cells with inducible caspase-9

por Kemper, Kristel, Rodermond, Hans, Colak, Selçuk, Grandela, Catarina, Medema, Jan Paul
Publicado 2012

Immune Escape of Tumors in Vivo by Expression of Cellular Flice-Inhibitory Protein

por Medema, Jan Paul, de Jong, Joan, van Hall, Thorbald, Melief, Cornelis J.M., Offringa, Rienk
Publicado 1999

FACS-based protocol to assess cytotoxicity and clonogenic potential of colorectal cancer stem cells using a Wnt/β-catenin signaling pathway reporter

por Di Franco, Simone, Zhang, Le, Gaggianesi, Miriam, Lo Iacono, Melania, Medema, Jan Paul, Stassi, Giorgio
Publicado 2021

Regulation of stem cell self-renewal and differentiation by Wnt and Notch are conserved throughout the adenoma-carcinoma sequence in the colon

por Prasetyanti, Pramudita Ramadhina, Zimberlin, Cheryl Doreen, Bots, Michael, Vermeulen, Louis, De Sousa E Melo, Felipe, Medema, Jan Paul
Publicado 2013

CD44 Expression in Intestinal Epithelium and Colorectal Cancer Is Independent of p53 Status

por Zeilstra, Jurrit, Joosten, Sander P. J., Vermeulen, Louis, Koster, Jan, Medema, Jan Paul, Versteeg, Rogier, Spaargaren, Marcel, Pals, Steven T.
Publicado 2013

Targeting DNA double strand break repair with hyperthermia and DNA-PKcs inhibition to enhance the effect of radiation treatment

por van Oorschot, Bregje, Granata, Giovanna, Di Franco, Simone, Cate, Rosemarie ten, Rodermond, Hans M., Todaro, Matilde, Medema, Jan Paul, Franken, Nicolaas A.P.
Publicado 2016

Expression and Function of Granzymes A and B in Escherichia coli Peritonitis and Sepsis

por García-Laorden, M. Isabel, Stroo, Ingrid, Terpstra, Sanne, Florquin, Sandrine, Medema, Jan Paul, van´t Veer, Cornelis, de Vos, Alex F., van der Poll, Tom
Publicado 2017

Patched-2 functions to limit Patched-1 deficient skin cancer growth

por Veenstra, Veronique L., Dingjan, Ilse, Waasdorp, Cynthia, Damhofer, Helene, van der Wal, Allard C., van Laarhoven, Hanneke W., Medema, Jan Paul, Bijlsma, Maarten F.
Publicado 2018

Activation of the Granzyme Pathway in Children With Severe Respiratory Syncytial Virus Infection

por Bem, Reinout A, Bos, Albert P, Bots, Michael, Wolbink, Angela M, van Ham, S Marieke, Medema, Jan Paul, Lutter, Rene, van Woensel, Job B M
Publicado 2008

Fusion of intestinal epithelial cells with bone marrow derived cells is dispensable for tissue homeostasis

por de Jong, Joan H., Rodermond, Hans M., Zimberlin, Cheryl D., Lascano, Valeria, De Sousa E Melo, Felipe, Richel, Dick J., Medema, Jan Paul, Vermeulen, Louis
Publicado 2012